Denali Therapeutics (DNLI) EBITDA Margin (2018 - 2026)
Denali Therapeutics' EBITDA Margin was -687.70% in Q3 2026, up 2809.99 percentage points from the prior quarter.
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Analysis
Denali Therapeutics (DNLI) EBITDA Margin (2018 - 2026) Analysis & Trends
On a trailing twelve-month basis, Denali Therapeutics' EBITDA Margin was -2410.81% through Sep 30, 2026; for FY2023, it was -54.45%, up 250.12 percentage points from FY2022.
- EBITDA Margin shows a five-year change of -24.29 percentage points (FY2018 to FY2023).
- In earlier years, EBITDA Margin was -304.57% in FY2022 (+285.54 pp), -590.11% in FY2021 (-611.33 pp), 21.23% in FY2020 (+790.34 pp) and -769.11% in FY2019 (-738.95 pp).
- The Q3 2026 figure marks the highest quarterly EBITDA Margin since Q2 2023.
- The best year-over-year quarter for EBITDA Margin over five years was Q1 2022 (a gain of 719.43 percentage points); the worst was Q3 2023 (a drop of 5846.51 percentage points).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,264.65 Bn | 1,238.27 Bn | 20.46 Bn | 54.65% |
| 2 | Johnson & Johnson | 677.74 Bn | 597.60 Bn | 17.30 Bn | 32.68% |
| 3 | AbbVie | 517.10 Bn | 485.11 Bn | 13.12 Bn | 46.88% |
| 4 | Merck | 362.23 Bn | 325.17 Bn | 13.19 Bn | 40.75% |
| 5 | Novartis Ag | 315.90 Bn | 276.16 Bn | 11.24 Bn | - |
| 6 | Astrazeneca | 289.40 Bn | 266.24 Bn | 12.86 Bn | - |
| 7 | Amgen | 249.90 Bn | 201.56 Bn | 7.58 Bn | 46.62% |
| 8 | Gilead Sciences | 209.15 Bn | 184.26 Bn | 6.73 Bn | 50.63% |
| 9 | Pfizer | 165.88 Bn | 113.23 Bn | 12.56 Bn | 42.49% |
| 10 | Denali Therapeutics | 3.83 Bn | 743.92 Mn | 17.59 Mn | -687.70% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Sep 30, 2026 | -687.70% |
| Jun 30, 2026 | -3,497.70% |
| Sep 30, 2023 | -8,806.47% |
| Jun 30, 2023 | 58.74% |
| Mar 31, 2023 | -315.21% |
| Dec 31, 2022 | -984.50% |
| Sep 30, 2022 | -2,959.96% |
| Jun 30, 2022 | -113.08% |
| Mar 31, 2022 | -152.87% |
| Dec 31, 2021 | -599.49% |
| Sep 30, 2021 | -1,578.16% |
| Jun 30, 2021 | -259.88% |
| Mar 31, 2021 | -872.30% |
| Dec 31, 2020 | 77.71% |
| Sep 30, 2020 | -617.06% |
| Jun 30, 2020 | -1,011.32% |
| Mar 31, 2020 | -1,605.38% |
| Dec 31, 2019 | -1,192.08% |
| Sep 30, 2019 | -354.79% |
| Jun 30, 2019 | -1,456.28% |
API Access
Denali Therapeutics EBITDA Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=ebitda-margin&ticker=DNLI&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "ebitda-margin", "ticker": "DNLI", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=ebitda-margin&ticker=DNLI&period=max&api_key=YOUR_API_KEY");
const data = await res.json();