Denali Therapeutics (DNLI) Research & Development (2017 - 2026)
Denali Therapeutics' Research & Development came in at $97.02 million for Q2 2026, down 5.5% from $102.7 million a year earlier and down 6.6% from the prior quarter.
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Analysis
Denali Therapeutics (DNLI) Research & Development (2017 - 2026) Analysis & Trends
Over the trailing twelve months to Jun 30, 2026, Denali Therapeutics reported Research & Development of $400.72 million, down 3.9% year-over-year; for FY2025, it came in at $418.78 million, up 5.6% from FY2024.
- Research & Development carries a five-year compound annual growth rate of 14.5% (FY2020 to FY2025).
- Going back by year, Research & Development was $396.44 million in FY2024 (-6.5%), $423.88 million in FY2023 (+18.2%), $358.73 million in FY2022 (+35.2%) and $265.35 million in FY2021 (+24.8%).
- The Q2 2026 figure represents the lowest quarterly Research & Development since Q2 2024.
- Year-over-year, Research & Development has declined for three consecutive quarters, with growth averaging 1.1% over the last eight quarters.
- The fastest year-over-year change in Research & Development over five years came in Q1 2023 (growth of 49.6%), and the weakest in Q1 2024 (a decline of 16.9%).
- Business Quant data shows DNLI's Research & Development at $103.85 million (Q1 2026), $97.91 million (Q4 2025) and $101.95 million (Q3 2025) in the three quarters before Q2 2026.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | R&D (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 3.65 Bn |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 2.34 Bn |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | 9.74 Bn |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | -2.85 Bn |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | -4.05 Bn |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 1.87 Bn |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | 1.76 Bn |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 2.81 Bn |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 993.80 Mn |
| 10 | Denali Therapeutics | 3.35 Bn | 3.35 Bn | 3.51 Mn | 97.02 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 97.02 Mn |
| Mar 31, 2026 | 103.85 Mn |
| Dec 31, 2025 | 97.91 Mn |
| Sep 30, 2025 | 101.95 Mn |
| Jun 30, 2025 | 102.70 Mn |
| Mar 31, 2025 | 116.23 Mn |
| Dec 31, 2024 | 99.79 Mn |
| Sep 30, 2024 | 98.24 Mn |
| Jun 30, 2024 | 91.40 Mn |
| Mar 31, 2024 | 107.02 Mn |
| Dec 31, 2023 | 107.80 Mn |
| Sep 30, 2023 | 89.74 Mn |
| Jun 30, 2023 | 97.52 Mn |
| Mar 31, 2023 | 128.82 Mn |
| Dec 31, 2022 | 92.11 Mn |
| Sep 30, 2022 | 87.79 Mn |
| Jun 30, 2022 | 92.74 Mn |
| Mar 31, 2022 | 86.10 Mn |
| Dec 31, 2021 | 67.88 Mn |
| Sep 30, 2021 | 71.56 Mn |
API Access
Denali Therapeutics Research & Development API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=research-and-development&ticker=DNLI&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "research-and-development", "ticker": "DNLI", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=research-and-development&ticker=DNLI&period=max&api_key=YOUR_API_KEY");
const data = await res.json();