Denali Therapeutics (DNLI) Enterprise Value (2017 - 2026)

Denali Therapeutics' (DNLI) quarterly Enterprise Value came in at -$987.7 million in Q1 2026, down 20.75% year-on-year from -$1.2 billion in Q1 2025, and down 13.8% on a QoQ basis from -$867.9 million in Q4 2025.

Denali Therapeutics (DNLI) Enterprise Value (2017 - 2026) Analysis & Trends

Denali Therapeutics (DNLI) has 10 years of Enterprise Value data on file, last reported at -$987.7 million in Q1 2026.

  • On a quarterly basis, Enterprise Value fell 20.75% year-over-year to -$987.7 million in Q1 2026; TTM through Mar 2026 was -$987.7 million, a 20.75% decrease from a year earlier, with the FY2025 full-year figure at -$867.9 million, down 4.27% from the prior year.
  • Enterprise Value for Q1 2026 stood at -$987.7 million, down from -$867.9 million in the prior quarter.
  • Over the last five years, Enterprise Value for DNLI reached as high as -$817.9 million in Q1 2025 and fell as low as -$1.3 billion in Q4 2022.
  • Historically, Enterprise Value has averaged -$1.0 billion across 5 years, with a median of -$957.5 million in 2022.
  • On a YoY basis, Enterprise Value climbed as much as 32.24% in 2022 and fell as far as 54.4% in 2022.
  • Year by year, Enterprise Value stood at -$1.3 billion in 2022, then climbed by 22.58% to -$1.0 billion in 2023, then advanced by 19.54% to -$832.3 million in 2024, then fell by 4.27% to -$867.9 million in 2025, then retreated by 13.8% to -$987.7 million in 2026.
  • Per Business Quant data, the three most recent Enterprise Value figures were -$987.7 million in Q1 2026, -$867.9 million in Q4 2025, and -$848.2 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -283.54 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -61.40 Mn
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn -4.79 Bn
4 NuCana 279.75 Bn 279.75 Bn - -32.26 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn -7.25 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn -8.75 Bn
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -5.18 Bn
9 Revolution Medicines 37.78 Bn 37.78 Bn - -1.91 Bn
10 Denali Therapeutics 4.37 Bn 4.37 Bn - -987.68 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -987.68 Mn
Dec 31, 2025 -867.88 Mn
Sep 30, 2025 -848.20 Mn
Jun 30, 2025 -898.95 Mn
Mar 31, 2025 -817.93 Mn
Dec 31, 2024 -832.33 Mn
Sep 30, 2024 -836.56 Mn
Jun 30, 2024 -896.04 Mn
Mar 31, 2024 -936.87 Mn
Dec 31, 2023 -1.03 Bn
Sep 30, 2023 -1.11 Bn
Jun 30, 2023 -1.19 Bn
Mar 31, 2023 -1.29 Bn
Dec 31, 2022 -1.34 Bn
Sep 30, 2022 -1.11 Bn
Jun 30, 2022 -1.07 Bn
Mar 31, 2022 -957.52 Mn
Dec 31, 2021 -865.41 Mn
Sep 30, 2021 -1.04 Bn
Jun 30, 2021 -1.31 Bn