Denali Therapeutics (DNLI) Enterprise Value (2017 - 2026)
Denali Therapeutics (DNLI) reported Enterprise Value of -$987.7 million for Q1 2026, down 20.75% year-over-year from -$1.2 billion in Q1 2025, and down 13.8% quarter-over-quarter from -$867.9 million in Q4 2025.
Denali Therapeutics (DNLI) Enterprise Value (2017 - 2026) Analysis & Trends
Denali Therapeutics (DNLI) has 10 years of Enterprise Value data on file, last reported at -$987.7 million in Q1 2026.
- Enterprise Value for Q1 2026 came in at -$987.7 million, down 20.75% year-over-year; the trailing twelve-month figure through Mar 2026 was -$987.7 million (down 20.75% YoY), and the FY2025 annual result was -$867.9 million, down 4.27% from the prior year.
- Enterprise Value fell to -$987.7 million in Q1 2026 per DNLI's latest filing, from -$867.9 million in the prior quarter.
- Over five years, Enterprise Value peaked at -$817.9 million in Q1 2025 and troughed at -$1.3 billion in Q4 2022.
- A 5-year average of -$1.0 billion and a median of -$957.5 million in 2022 frame the typical range for Enterprise Value.
- On a YoY basis, Enterprise Value climbed as much as 32.24% in 2022 and fell as far as 54.4% in 2022.
- A 5-year view of Enterprise Value shows it stood at -$1.3 billion in 2022, then rose by 22.58% to -$1.0 billion in 2023, then increased by 19.54% to -$832.3 million in 2024, then slipped by 4.27% to -$867.9 million in 2025, then dropped by 13.8% to -$987.7 million in 2026.
- Business Quant data shows DNLI's Enterprise Value at -$987.7 million in Q1 2026, -$867.9 million in Q4 2025, and -$848.2 million in Q3 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Enterprise Value (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | -32.30 Mn |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | -4.14 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -286.70 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | -18.44 Mn |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -2.77 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | -7.20 Mn |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | -7.25 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -584.73 Mn |
| 10 | Denali Therapeutics | 4.35 Bn | 4.35 Bn | - | -987.68 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -987.68 Mn |
| Dec 31, 2025 | -867.88 Mn |
| Sep 30, 2025 | -848.20 Mn |
| Jun 30, 2025 | -898.95 Mn |
| Mar 31, 2025 | -817.93 Mn |
| Dec 31, 2024 | -832.33 Mn |
| Sep 30, 2024 | -836.56 Mn |
| Jun 30, 2024 | -896.04 Mn |
| Mar 31, 2024 | -936.87 Mn |
| Dec 31, 2023 | -1.03 Bn |
| Sep 30, 2023 | -1.11 Bn |
| Jun 30, 2023 | -1.19 Bn |
| Mar 31, 2023 | -1.29 Bn |
| Dec 31, 2022 | -1.34 Bn |
| Sep 30, 2022 | -1.11 Bn |
| Jun 30, 2022 | -1.07 Bn |
| Mar 31, 2022 | -957.52 Mn |
| Dec 31, 2021 | -865.41 Mn |
| Sep 30, 2021 | -1.04 Bn |
| Jun 30, 2021 | -1.31 Bn |