Denali Therapeutics (DNLI) Enterprise Value (2017 - 2026)
Denali Therapeutics' (DNLI) quarterly Enterprise Value came in at -$987.7 million in Q1 2026, down 20.75% year-on-year from -$1.2 billion in Q1 2025, and down 13.8% on a QoQ basis from -$867.9 million in Q4 2025.
Denali Therapeutics (DNLI) Enterprise Value (2017 - 2026) Analysis & Trends
Denali Therapeutics (DNLI) has 10 years of Enterprise Value data on file, last reported at -$987.7 million in Q1 2026.
- On a quarterly basis, Enterprise Value fell 20.75% year-over-year to -$987.7 million in Q1 2026; TTM through Mar 2026 was -$987.7 million, a 20.75% decrease from a year earlier, with the FY2025 full-year figure at -$867.9 million, down 4.27% from the prior year.
- Enterprise Value for Q1 2026 stood at -$987.7 million, down from -$867.9 million in the prior quarter.
- Over the last five years, Enterprise Value for DNLI reached as high as -$817.9 million in Q1 2025 and fell as low as -$1.3 billion in Q4 2022.
- Historically, Enterprise Value has averaged -$1.0 billion across 5 years, with a median of -$957.5 million in 2022.
- On a YoY basis, Enterprise Value climbed as much as 32.24% in 2022 and fell as far as 54.4% in 2022.
- Year by year, Enterprise Value stood at -$1.3 billion in 2022, then climbed by 22.58% to -$1.0 billion in 2023, then advanced by 19.54% to -$832.3 million in 2024, then fell by 4.27% to -$867.9 million in 2025, then retreated by 13.8% to -$987.7 million in 2026.
- Per Business Quant data, the three most recent Enterprise Value figures were -$987.7 million in Q1 2026, -$867.9 million in Q4 2025, and -$848.2 million in Q3 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Enterprise Value (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | -283.54 Mn |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | -61.40 Mn |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | -4.79 Bn |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | -32.26 Mn |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | -7.25 Bn |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | -8.75 Bn |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | - |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | -5.18 Bn |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | -1.91 Bn |
| 10 | Denali Therapeutics | 4.37 Bn | 4.37 Bn | - | -987.68 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -987.68 Mn |
| Dec 31, 2025 | -867.88 Mn |
| Sep 30, 2025 | -848.20 Mn |
| Jun 30, 2025 | -898.95 Mn |
| Mar 31, 2025 | -817.93 Mn |
| Dec 31, 2024 | -832.33 Mn |
| Sep 30, 2024 | -836.56 Mn |
| Jun 30, 2024 | -896.04 Mn |
| Mar 31, 2024 | -936.87 Mn |
| Dec 31, 2023 | -1.03 Bn |
| Sep 30, 2023 | -1.11 Bn |
| Jun 30, 2023 | -1.19 Bn |
| Mar 31, 2023 | -1.29 Bn |
| Dec 31, 2022 | -1.34 Bn |
| Sep 30, 2022 | -1.11 Bn |
| Jun 30, 2022 | -1.07 Bn |
| Mar 31, 2022 | -957.52 Mn |
| Dec 31, 2021 | -865.41 Mn |
| Sep 30, 2021 | -1.04 Bn |
| Jun 30, 2021 | -1.31 Bn |