Denali Therapeutics (DNLI) Enterprise Value (2017 - 2025)

Denali Therapeutics (DNLI) has disclosed Enterprise Value for 9 consecutive years, with -$848.2 million as the latest value for Q3 2025.

  • On a quarterly basis, Enterprise Value fell 13.71% to -$848.2 million in Q3 2025 year-over-year; TTM through Dec 2025 was -$2.3 billion, a 172.08% decrease, with the full-year FY2024 number at -$832.3 million, up 19.54% from a year prior.
  • Enterprise Value was -$848.2 million for Q3 2025 at Denali Therapeutics, down from -$757.7 million in the prior quarter.
  • In the past five years, Enterprise Value ranged from a high of -$485.7 million in Q2 2021 to a low of -$1.4 billion in Q1 2021.
  • A 5-year average of -$937.4 million and a median of -$876.3 million in 2024 define the central range for Enterprise Value.
  • Biggest YoY gain for Enterprise Value was 41.12% in 2021; the steepest drop was 272.16% in 2021.
  • Denali Therapeutics' Enterprise Value stood at -$865.4 million in 2021, then tumbled by 54.4% to -$1.3 billion in 2022, then grew by 22.58% to -$1.0 billion in 2023, then rose by 19.54% to -$832.3 million in 2024, then dropped by 1.91% to -$848.2 million in 2025.
  • Per Business Quant, the three most recent readings for DNLI's Enterprise Value are -$848.2 million (Q3 2025), -$757.7 million (Q2 2025), and -$761.0 million (Q1 2025).