Denali Therapeutics's top three insider shareholders as of May 30, 2026 are Bros. Advisors Lp Baker (Director, 3.42Mn shares), Ryan J. Watts (President And Ceo, 2.15Mn shares), Marc Tessier-Lavigne (Director, 1.89Mn shares).
| Holder | Position | Shares (Direct) | Shares (Indirect) | Report Date |
|---|---|---|---|---|
| Jay T Flatley | - | 0 | 340,529 | 05 Jun, 2023 |
| Vicki L Sato | - | 107,976 | 0 | 03 Jan, 2025 |
| Bros. Advisors Lp Baker | - | 0 | 3,415,958 | 05 Jun, 2025 |
| Marc Tessier-Lavigne | - | 1,886,576 | 0 | 05 Jun, 2025 |
| Peter S Klein | - | 27,533 | 0 | 05 Jun, 2025 |
| Douglas G. Cole | - | 26,564 | 0 | 05 Jun, 2023 |
| David P Schenkein | - | 15,257 | 0 | 05 Jun, 2025 |
| Steve E. Krognes | Cfo And Treasurer | 31,794 | 0 | 05 Jun, 2025 |
| Ryan J. Watts | President And Ceo | 0 | 2,152,604 | 05 Sep, 2025 |
| Alexander O. Schuth | Cofo And Secretary | 0 | 539,307 | 09 Jan, 2024 |
| Carole Ho | Chief Medical Officer | 216,585 | 0 | 14 Aug, 2025 |
| Jennifer E. Cook | - | 26,075 | 0 | 05 Jun, 2025 |
| Erik Harris | - | 17,052 | 0 | 04 Jun, 2024 |
* Please note that the shares above only reflect shares from the fund portfolio and the institutional portfolio. Shares from the personal portfolio are excluded from this Institutional Ownership Page. See these insiders' latest transactions here on Insider Page.
| Transaction Date | Insider Name | Security Class | Transaction Type | Shares Traded | Price | Shares Remaining | Ownership | Code |
|---|---|---|---|---|---|---|---|---|
| 06 Jan, 2026 | Ryan J. Watts | Common Stock | D | 35,198 | $16.50 | 296,833 | D | S |
| 06 Jan, 2026 | Ryan J. Watts | Common Stock | D | 35,198 | $16.50 | 296,833 | D | S |
| 06 Jan, 2026 | Alexander O. Schuth | Common Stock | D | 17,218 | $16.50 | 282,828 | D | S |
| 06 Jan, 2026 | Alexander O. Schuth | Common Stock | D | 17,218 | $16.50 | 282,828 | D | S |
| 03 Jan, 2026 | Alexander O. Schuth | Common Stock | A | 57,700 | $0.00 | 300,046 | D | A |
| 03 Jan, 2026 | Ryan J. Watts | Common Stock | A | 78,960 | $0.00 | 332,031 | D | A |
| 03 Jan, 2026 | Ryan J. Watts | Common Stock | A | 78,960 | $0.00 | 332,031 | D | A |
| 03 Jan, 2026 | Alexander O. Schuth | Common Stock | A | 57,700 | $0.00 | 300,046 | D | A |
| 03 Jan, 2026 | Ryan J. Watts | Stock Option (right to buy) | A | 236,880 | $0.00 | 236,880 | D | A |
| 03 Jan, 2026 | Alexander O. Schuth | Stock Option (right to buy) | A | 173,100 | $0.00 | 173,100 | D | A |
| 03 Jan, 2026 | Alexander O. Schuth | Stock Option (right to buy) | A | 173,100 | $0.00 | 173,100 | D | A |
| 03 Jan, 2026 | Ryan J. Watts | Stock Option (right to buy) | A | 236,880 | $0.00 | 236,880 | D | A |
| 11 Dec, 2025 | Bros. Advisors Lp Baker | $0.01 Prefunded Warrants | A | 190,523 | $17.49 | 2,335,469 | I | P |
| 11 Dec, 2025 | Bros. Advisors Lp Baker | $0.01 Prefunded Warrants | A | 2,095,191 | $17.49 | 25,996,310 | I | P |
| 03 Sep, 2025 | Ryan J. Watts | Common Stock | D | 50,000 | $0.00 | 2,152,604 | I | G |
| 03 Sep, 2025 | Ryan J. Watts | Common Stock | D | 50,000 | $0.00 | 2,152,604 | I | G |
| 12 Aug, 2025 | Carole Ho | Common Stock | D | 2,937 | $13.58 | 217,391 | D | S |
| 12 Aug, 2025 | Alexander O. Schuth | Common Stock | D | 2,937 | $13.58 | 242,346 | D | S |
| 12 Aug, 2025 | Alexander O. Schuth | Common Stock | D | 2,937 | $13.58 | 242,346 | D | S |
| 13 Aug, 2025 | Carole Ho | Common Stock | D | 806 | $14.64 | 216,585 | D | S |