Denali Therapeutics Inc. (DNLI) Insider Ownership

Historic Insider Ownership Trends

Through the 90-day period concluding January 09, 2026, Denali Therapeutics's top three insider stakeholders include Director Bros. Advisors Lp Baker (3.42Mn shares), President And Ceo Ryan J. Watts (2.45Mn shares), Director Marc Tessier-Lavigne (1.97Mn shares).

Top Direct Holders

Insider ownership data is derived from the last 60 months of Form 4 SEC filings.
Holder Position Shares Report Date
Bros. Advisors Lp Baker 3,415,958 05 Jun, 2025
Ryan J. Watts President And Ceo 2,449,437 08 Jan, 2026
Marc Tessier-Lavigne 1,965,424 05 Jun, 2025
Alexander O. Schuth Cofo And Secretary 822,135 08 Jan, 2026
Carole Ho Chief Medical Officer 415,362 14 Aug, 2025
Jay T Flatley 356,749 05 Jun, 2025
Vicki L Sato 107,976 03 Jan, 2025
Steve E. Krognes 31,794 05 Jun, 2025
Peter S Klein 27,533 05 Jun, 2025
Douglas G. Cole 26,564 05 Jun, 2023
Jennifer E. Cook 26,075 05 Jun, 2025
Nancy Thornberry 24,717 05 Jun, 2025
Erik Harris 17,052 04 Jun, 2024
David P Schenkein 15,257 05 Jun, 2025
Robert Nelsen 12,432 04 Jun, 2021
Hauwermeiren Timothy Van 10,632 06 Nov, 2025

* Please note that the shares above only reflect shares from the fund portfolio and the institutional portfolio. Shares from the personal portfolio are excluded from this Institutional Ownership Page. See these insiders' latest transactions here on Insider Page.

Recent Insider Transactions

Detailed insider trading activity based on Form 4 SEC filings.
Download Data
Transaction Date Insider Name Security Class Transaction Type Shares Traded Price Shares Remaining Ownership Code
06 Jan, 2026 Ryan J. Watts Common Stock D 35,198 $16.50 296,833 D S
06 Jan, 2026 Alexander O. Schuth Common Stock D 17,218 $16.50 282,828 D S
03 Jan, 2026 Ryan J. Watts Common Stock A 78,960 $0.00 332,031 D A
03 Jan, 2026 Alexander O. Schuth Common Stock A 57,700 $0.00 300,046 D A
04 Nov, 2025 Hauwermeiren Timothy Van - - 10,632 D
04 Nov, 2025 Hauwermeiren Timothy Van Common Stock A 10,632 $0.00 10,632 D A
03 Sep, 2025 Ryan J. Watts Common Stock D 50,000 $0.00 2,152,604 I G
03 Sep, 2025 Ryan J. Watts - - 2,152,604 I
13 Aug, 2025 Carole Ho - - 216,585 D
13 Aug, 2025 Carole Ho Common Stock D 806 $14.64 216,585 D S
12 Aug, 2025 Alexander O. Schuth Common Stock D 2,937 $13.58 242,346 D S
12 Aug, 2025 Alexander O. Schuth - - 242,346 D
12 Aug, 2025 Carole Ho Common Stock D 2,937 $13.58 217,391 D S
05 Aug, 2025 Carole Ho Common Stock A 44,655 $0.68 220,328 D M
05 Aug, 2025 Carole Ho - - 220,328 D
09 Jul, 2025 Ryan J. Watts - - 708,353 D
09 Jul, 2025 Ryan J. Watts - - 748,353 D
09 Jul, 2025 Ryan J. Watts - - 253,071 D
09 Jul, 2025 Ryan J. Watts Common Stock D 495,282 $15.00 253,071 D S
09 Jul, 2025 Ryan J. Watts Common Stock A 40,000 $5.28 748,353 D M