Denali Therapeutics's top three insider shareholders as of September 29, 2026 are Bros. Advisors Lp Baker (Director, 3.42Mn shares), Ryan J. Watts (President And Ceo, 2.12Mn shares), Marc Tessier-Lavigne (Director, 1.89Mn shares).
| # | Insider | Position | Direct | Indirect | Total | Share of Insiders | Last Filed |
|---|---|---|---|---|---|---|---|
| 1 | Bros. Advisors Lp Baker | Director | 0 | 3,422,366 | 3,422,366 | 40.4% | 05 Jun, 2026 |
| 2 | Ryan J. Watts | President And Ceo | 0 | 2,120,384 | 2,120,384 | 25.0% | 14 Aug, 2026 |
| 3 | Marc Tessier-Lavigne | Director | 1,886,576 | 0 | 1,886,576 | 22.3% | 05 Jun, 2025 |
| 4 | Alexander O. Schuth | Cofo And Secretary | 278,995 | 0 | 278,995 | 3.3% | 03 Sep, 2026 |
| 5 | Carole Ho | Chief Medical Officer | 216,585 | 0 | 216,585 | 2.6% | 14 Aug, 2025 |
| 6 | Peter Scott Chin | Chief Medical Officer | 204,538 | 0 | 204,538 | 2.4% | 09 Sep, 2026 |
| 7 | Vicki L Sato | Director | 107,976 | 0 | 107,976 | 1.3% | 03 Jan, 2025 |
| 8 | Steve E. Krognes | Cfo And Treasurer | 38,202 | 0 | 38,202 | 0.5% | 05 Jun, 2026 |
| 9 | Peter S Klein | Director | 33,941 | 0 | 33,941 | 0.4% | 05 Jun, 2026 |
| 10 | Jennifer E. Cook | Director | 32,483 | 0 | 32,483 | 0.4% | 05 Jun, 2026 |
| 11 | Douglas G. Cole | Director | 26,564 | 0 | 26,564 | 0.3% | 05 Jun, 2023 |
| 12 | Jay T Flatley | Director | 22,628 | 0 | 22,628 | 0.3% | 05 Jun, 2026 |
| 13 | David P Schenkein | Director | 21,665 | 0 | 21,665 | 0.3% | 05 Jun, 2026 |
| 14 | Nancy Thornberry | Director | 19,686 | 0 | 19,686 | 0.2% | 04 Sep, 2026 |
| 15 | Erik Harris | Director | 17,052 | 0 | 17,052 | 0.2% | 04 Jun, 2024 |
| 16 | Hauwermeiren Timothy Van | Director | 17,040 | 0 | 17,040 | 0.2% | 05 Jun, 2026 |
Each row is that insider’s most recently reported position, from Form 4 filings over the last 60 months — which is why this total does not tie to the quarterly series above, where a quarter counts only the insiders who filed in it. Shares held through a fund or institutional portfolio are counted on the institutional ownership page instead.
| Date | Insider | Position | Transaction | Shares | Price | Value | Shares Held After | Ownership |
|---|---|---|---|---|---|---|---|---|
| 04 Sep, 2026 | Peter Scott Chin | Chief Medical Officer | Disposed S | 1,654 | $22.29 | $36.87K | 204,538 | Direct |
| 02 Sep, 2026 | Nancy Thornberry | Director | Disposed S | 10,824 | $22.85 | $247.33K | 20,301 | Direct |
| 02 Sep, 2026 | Nancy Thornberry | Director | Disposed S | 615 | $23.74 | $14.60K | 19,686 | Direct |
| 01 Sep, 2026 | Alexander O. Schuth | Cofo And Secretary | Disposed S | 2,768 | $23.44 | $64.88K | 278,995 | Direct |
| 12 Aug, 2026 | Ryan J. Watts | President And Ceo | Disposed G | 32,220 | $0.00 | $0 | 2,120,384 | Indirect |
| 11 Aug, 2026 | Alexander O. Schuth | Cofo And Secretary | Disposed S | 2,857 | $25.07 | $71.62K | 281,763 | Direct |
| 03 Jun, 2026 | Steve E. Krognes | Director | Acquired A | 6,408 | $0.00 | $0 | 38,202 | Direct |
| 03 Jun, 2026 | David P Schenkein | Director | Acquired A | 6,408 | $0.00 | $0 | 21,665 | Direct |
| 03 Jun, 2026 | Hauwermeiren Timothy Van | Director | Acquired A | 6,408 | $0.00 | $0 | 17,040 | Direct |
| 03 Jun, 2026 | Peter S Klein | Director | Acquired A | 6,408 | $0.00 | $0 | 33,941 | Direct |
| 03 Jun, 2026 | Jennifer E. Cook | Director | Acquired A | 6,408 | $0.00 | $0 | 32,483 | Direct |
| 03 Jun, 2026 | Jay T Flatley | Director | Acquired A | 6,408 | $0.00 | $0 | 22,628 | Direct |
| 03 Jun, 2026 | Nancy Thornberry | Director | Acquired A | 6,408 | $0.00 | $0 | 31,125 | Direct |
| 03 Jun, 2026 | Bros. Advisors Lp Baker | Director | Acquired A | 6,408 | $0.00 | $0 | 343,275 | Indirect |
| 03 Jun, 2026 | Jennifer E. Cook | Director | Acquired A | 19,226 | $0.00 | $0 | 19,226 | Direct |
| 03 Jun, 2026 | Peter S Klein | Director | Acquired A | 19,226 | $0.00 | $0 | 19,226 | Direct |
| 03 Jun, 2026 | Bros. Advisors Lp Baker | Director | Acquired A | 6,408 | $0.00 | $0 | 3,422,366 | Indirect |
| 03 Jun, 2026 | Nancy Thornberry | Director | Acquired A | 19,226 | $0.00 | $0 | 19,226 | Direct |
| 03 Jun, 2026 | Hauwermeiren Timothy Van | Director | Acquired A | 19,226 | $0.00 | $0 | 19,226 | Direct |
| 03 Jun, 2026 | Steve E. Krognes | Director | Acquired A | 19,226 | $0.00 | $0 | 19,226 | Direct |