Denali Therapeutics (DNLI) Consolidated Net Income (2017 - 2026)

Denali Therapeutics (DNLI) reported Consolidated Net Income of -$128.4 million for Q1 2026, up 3.4% year-over-year from -$124.2 million in Q1 2025, and little changed on a QoQ basis from -$128.4 million in Q4 2025.

Denali Therapeutics (DNLI) has 10 years of Consolidated Net Income data on file, last reported at -$128.4 million in Q1 2026.

  • Quarterly Consolidated Net Income rose 3.4% year-over-year to -$128.4 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$507.9 million (down 11.91% YoY) and the FY2025 annual result came in at -$512.5 million, down 21.23% from the prior year.
  • Consolidated Net Income steadied at -$128.4 million in Q1 2026 per DNLI's latest filing, from -$128.4 million in the prior quarter.
  • Across five years, Consolidated Net Income topped out at $183.4 million in Q2 2023 and bottomed at -$133.0 million in Q1 2025.
  • The 5-year median for Consolidated Net Income is -$107.2 million (2024), against an average of -$90.4 million.
  • The widest annual swing landed in 2023, when Consolidated Net Income surged 411.91%; it then sank 154.0% in 2024.
  • Tracing DNLI's Consolidated Net Income over 5 years: stood at -$98.7 million in 2022, then retreated by 21.07% to -$119.5 million in 2023, then grew by 4.01% to -$114.7 million in 2024, then dropped by 12.0% to -$128.4 million in 2025, then changed by 0.0% to -$128.4 million in 2026.
  • Per Business Quant, the three latest DNLI Consolidated Net Income figures stand at -$128.4 million (Q1 2026), -$128.4 million (Q4 2025), and -$126.9 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Consol Net Inc. (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -2.99 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -8.40 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -14.46 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 1.03 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -3.40 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 727.20 Mn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 205.99 Mn
10 Denali Therapeutics 3.82 Bn 3.82 Bn - -128.45 Mn

Historic Data

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DateValue
Mar 31, 2026 -128.45 Mn
Dec 31, 2025 -128.45 Mn
Sep 30, 2025 -126.90 Mn
Jun 30, 2025 -124.12 Mn
Mar 31, 2025 -132.97 Mn
Dec 31, 2024 -114.69 Mn
Sep 30, 2024 -107.19 Mn
Jun 30, 2024 -99.03 Mn
Mar 31, 2024 -101.80 Mn
Dec 31, 2023 -119.47 Mn
Sep 30, 2023 -99.35 Mn
Jun 30, 2023 183.38 Mn
Mar 31, 2023 -109.78 Mn
Dec 31, 2022 -98.68 Mn
Sep 30, 2022 -103.30 Mn
Jun 30, 2022 -58.79 Mn
Mar 31, 2022 -66.50 Mn
Dec 31, 2021 -75.26 Mn
Sep 30, 2021 -84.59 Mn
Jun 30, 2021 -60.69 Mn
Mar 31, 2021 -70.04 Mn
Dec 31, 2020 244.89 Mn
Sep 30, 2020 -58.23 Mn
Jun 30, 2020 -58.76 Mn
Mar 31, 2020 -56.76 Mn
Dec 31, 2019 -57.76 Mn
Sep 30, 2019 -46.26 Mn
Jun 30, 2019 -58.34 Mn
Mar 31, 2019 -38.99 Mn
Dec 31, 2018 77.53 Mn
Sep 30, 2018 -35.37 Mn
Jun 30, 2018 -54.72 Mn
Mar 31, 2018 -25.75 Mn
Dec 31, 2017 -23.54 Mn
Sep 30, 2017 -22.29 Mn
Jun 30, 2017 -22.57 Mn
Mar 31, 2017 -21.74 Mn