Growth Metrics

Legend Biotech (LEGN) Return on Capital Employed (2020 - 2025)

Legend Biotech (LEGN) posted Return on Capital Employed of 51.73% for Q4 2025, up 30.48% on a QoQ basis from 39.64% in Q3 2025, and up 2665.0% year-over-year from 1.87% in Q4 2024.

Legend Biotech (LEGN) has 6 years of Return on Capital Employed data on file, last reported at 51.73% in Q4 2025.

  • In Q4 2025, Return on Capital Employed rose 2665.0% year-over-year to 51.73%; the TTM figure through Dec 2025 stood at 51.73% (up 2665.0% YoY), while the FY2025 annual figure was 12.81%, up 808.0% from the prior year.
  • Return on Capital Employed advanced to 51.73% in Q4 2025, from 39.64% in the prior quarter.
  • Across five years, Return on Capital Employed topped out at 5372.09% in Q2 2024 and bottomed at 2307.76% in Q3 2021.
  • A 5-year average of 999.88% and a median of 39.64% in 2025 frame the typical range for Return on Capital Employed.
  • Annual changes were most pronounced in 2024 — Return on Capital Employed jumped 533217 bps — and 2025, when it slumped 533780 bps.
  • Year by year, Return on Capital Employed stood at 1781.34% in 2021, then soared by 103 bps to 45.59% in 2022, then surged by 10676 bps to 4913.13% in 2023, then tumbled by 99 bps to 25.08% in 2024, then soared by 106 bps to 51.73% in 2025.
  • The last three Return on Capital Employed figures came in at 51.73% (Q4 2025), 39.64% (Q3 2025), and 34.29% (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - 450.31%
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn 51.73%
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -107.40%
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 21.10%
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 10.19%
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 20.34%
10 Revolution Medicines 32.39 Bn 32.39 Bn - -21.94%

Historic Data

Download Data 🔒
DateValue
Dec 31, 2025 51.73%
Sep 30, 2025 39.64%
Jun 30, 2025 34.29%
Mar 31, 2025 31.40%
Dec 31, 2024 25.08%
Sep 30, 2024 5,340.57%
Jun 30, 2024 5,372.09%
Mar 31, 2024 5,123.67%
Dec 31, 2023 4,913.13%
Sep 30, 2023 35.62%
Jun 30, 2023 39.93%
Mar 31, 2023 42.87%
Mar 31, 2022 45.59%
Dec 31, 2021 -1,781.34%
Sep 30, 2021 -2,307.76%
Jun 30, 2021 -4.27%
Mar 31, 2021 -4.28%
Dec 31, 2020 0.08%
Sep 30, 2020 0.04%