Denali Therapeutics (DNLI) Operating Leases (2019 - 2026)

Denali Therapeutics (DNLI) posted quarterly Operating Leases of $24.7 million for Q1 2026, down 42.65% year-over-year from $43.0 million in Q1 2025, and down 9.3% quarter-over-quarter from $27.2 million in Q4 2025.

Denali Therapeutics (DNLI) Operating Leases (2019 - 2026) Analysis & Trends

Denali Therapeutics (DNLI) has reported Operating Leases for 8 consecutive years, with $24.7 million the latest figure, recorded in Q1 2026.

  • In Q1 2026, Operating Leases fell 42.65% year-over-year to $24.7 million; the TTM figure through Mar 2026 stood at $24.7 million (down 42.65% YoY), while the FY2025 annual figure was $27.2 million, down 25.8% from the prior year.
  • Operating Leases retreated to $24.7 million in Q1 2026 per DNLI's latest filing, from $27.2 million in the prior quarter.
  • Across five years, Operating Leases topped out at $62.0 million in Q3 2022 and bottomed at $24.7 million in Q1 2026.
  • Historically, Operating Leases has averaged $45.4 million across 5 years, with a median of $46.9 million in 2024.
  • Annual changes were most pronounced in 2022 — Operating Leases rose 3.43% — and 2026, when it tumbled 42.65%.
  • Denali Therapeutics' Operating Leases stood at $53.0 million in 2022, then retreated by 15.18% to $45.0 million in 2023, then decreased by 18.47% to $36.7 million in 2024, then dropped by 25.8% to $27.2 million in 2025, then dropped by 9.3% to $24.7 million in 2026.
  • Business Quant data shows DNLI's Operating Leases at $24.7 million in Q1 2026, $27.2 million in Q4 2025, and $29.7 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn
4 Revolution Medicines 43.64 Bn 43.64 Bn -
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn
7 Royalty Pharma 33.72 Bn 35.84 Bn -
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn
10 Denali Therapeutics 3.90 Bn 3.90 Bn 3.51 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 22.03 Mn
Mar 31, 2026 24.68 Mn
Dec 31, 2025 27.21 Mn
Sep 30, 2025 29.69 Mn
Jun 30, 2025 32.11 Mn
Mar 31, 2025 43.03 Mn
Dec 31, 2024 36.67 Mn
Sep 30, 2024 46.89 Mn
Jun 30, 2024 48.75 Mn
Mar 31, 2024 43.03 Mn
Dec 31, 2023 44.98 Mn
Sep 30, 2023 53.90 Mn
Jun 30, 2023 55.53 Mn
Mar 31, 2023 57.09 Mn
Dec 31, 2022 53.03 Mn
Sep 30, 2022 62.05 Mn
Jun 30, 2022 55.53 Mn
Mar 31, 2022 57.09 Mn
Dec 31, 2021 58.55 Mn
Sep 30, 2021 59.99 Mn