Growth Metrics

Vertex Pharmaceuticals (VRTX) Return on Capital Employed (2010 - 2026)

Vertex Pharmaceuticals' quarterly Return on Capital Employed came in at 21.1% in Q1 2026, up 2503.0% year-on-year from 0.81% in Q1 2025, and up 8.17% quarter-over-quarter from 19.51% in Q4 2025.

Vertex Pharmaceuticals has reported Return on Capital Employed for 17 years, with the latest figure at 21.1% in Q1 2026.

  • For the quarter ending Q1 2026, Return on Capital Employed rose 2503.0% year-over-year to 21.1%; the trailing twelve-month figure through Mar 2026 stood at 21.1% (up 2503.0% YoY), and the FY2025 full-year result was 20.63%, up 2185.0% from the prior year.
  • Return on Capital Employed for Q1 2026 stood at 21.1%, up from 19.51% in the prior quarter.
  • The five-year high for Return on Capital Employed was 33.0% in Q2 2022, with the low at 3.92% in Q1 2025.
  • Average Return on Capital Employed over 5 years is 17.94%, with a median of 21.1% recorded in 2026.
  • Year-over-year, Return on Capital Employed sank 2620 bps in 2024 and soared 2503 bps in 2026.
  • Tracing VRTX's Return on Capital Employed over 5 years: stood at 29.33% in 2022, then tumbled by 30 bps to 20.51% in 2023, then slumped by 106 bps to 1.24% in 2024, then surged by 1677 bps to 19.51% in 2025, then gained by 8 bps to 21.1% in 2026.
  • The last three Return on Capital Employed figures came in at 21.1% (Q1 2026), 19.51% (Q4 2025), and 19.99% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - 450.31%
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn 51.73%
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -107.40%
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 21.10%
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 10.19%
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 20.34%
10 Revolution Medicines 32.39 Bn 32.39 Bn - -21.94%

Historic Data

Download Data 🔒
DateValue
Mar 31, 2026 21.10%
Dec 31, 2025 19.51%
Sep 30, 2025 19.99%
Jun 30, 2025 20.31%
Mar 31, 2025 -3.92%
Dec 31, 2024 -1.24%
Sep 30, 2024 -1.57%
Jun 30, 2024 -1.89%
Mar 31, 2024 21.47%
Dec 31, 2023 20.51%
Sep 30, 2023 22.23%
Jun 30, 2023 24.31%
Mar 31, 2023 26.04%
Dec 31, 2022 29.33%
Sep 30, 2022 30.67%
Jun 30, 2022 33.00%
Mar 31, 2022 25.16%
Dec 31, 2021 25.56%
Sep 30, 2021 25.23%
Jun 30, 2021 21.95%
Mar 31, 2021 30.27%
Dec 31, 2020 29.60%
Sep 30, 2020 30.41%
Jun 30, 2020 26.93%
Mar 31, 2020 23.22%
Dec 31, 2019 18.20%
Sep 30, 2019 13.15%
Jun 30, 2019 15.92%
Mar 31, 2019 14.81%
Dec 31, 2018 14.73%
Sep 30, 2018 18.17%
Jun 30, 2018 3.15%
Mar 31, 2018 -0.64%
Dec 31, 2017 4.80%
Sep 30, 2017 1.47%
Jun 30, 2017 13.83%
Mar 31, 2017 12.13%
Dec 31, 2016 0.51%
Sep 30, 2016 -4.49%
Jun 30, 2016 -7.11%
Mar 31, 2016 -15.93%
Dec 31, 2015 -23.82%
Sep 30, 2015 -27.93%
Jun 30, 2015 -33.70%
Mar 31, 2015 -33.29%
Dec 31, 2014 -34.58%
Sep 30, 2014 -29.05%
Jun 30, 2014 -29.56%
Mar 31, 2014 -21.06%
Dec 31, 2013 -29.71%
Sep 30, 2013 -31.15%
Jun 30, 2013 -26.33%
Mar 31, 2013 -23.91%
Dec 31, 2012 0.10%
Sep 30, 2012 13.47%
Jun 30, 2012 24.84%
Mar 31, 2012 19.36%
Dec 31, 2011 6.44%
Mar 31, 2011 -57.22%
Dec 31, 2010 -52.24%
Sep 30, 2010 -46.31%
Jun 30, 2010 -44.00%
Mar 31, 2010 -37.08%