Vertex Pharmaceuticals (VRTX) Return on Capital Employed (2010 - 2026)
Vertex Pharmaceuticals' (VRTX) quarterly Return on Capital Employed came in at 21.1% in Q1 2026, up 2503.0% year-on-year from 0.81% in Q1 2025, and up 8.17% quarter-over-quarter from 19.51% in Q4 2025.
Vertex Pharmaceuticals (VRTX) Return on Capital Employed (2010 - 2026) Analysis & Trends
Vertex Pharmaceuticals' Return on Capital Employed history runs 17 years deep, the most recent figure standing at 21.1% for Q1 2026.
- On a quarterly basis, Return on Capital Employed rose 2503.0% year-over-year to 21.1% in Q1 2026; TTM through Mar 2026 was 21.1%, a 2503.0% increase from a year earlier, with the FY2025 full-year figure at 20.63%, up 2185.0% from the prior year.
- Return on Capital Employed advanced to 21.1% in Q1 2026 per VRTX's latest filing, from 19.51% in the prior quarter.
- Across five years, Return on Capital Employed topped out at 33.0% in Q2 2022 and bottomed at 3.92% in Q1 2025.
- The 5-year median for Return on Capital Employed is 21.1% (2026), against an average of 17.94%.
- Across the five-year window, Return on Capital Employed sank 2620 bps in 2024 and soared 2503 bps in 2026, its largest moves.
- Year by year, Return on Capital Employed stood at 29.33% in 2022, then slumped by 30 bps to 20.51% in 2023, then sank by 106 bps to 1.24% in 2024, then jumped by 1677 bps to 19.51% in 2025, then rose by 8 bps to 21.1% in 2026.
- Per Business Quant, the three latest VRTX Return on Capital Employed figures stand at 21.1% (Q1 2026), 19.51% (Q4 2025), and 19.99% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROCE (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 67,072.09 Bn | 67,072.09 Bn | - | -31.80% |
| 2 | Nanobiotix | 1,894.61 Bn | 1,894.55 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | -107.40% |
| 4 | BeOne Medicines | 471.64 Bn | 466.85 Bn | 1.35 Bn | 10.46% |
| 5 | Vertex Pharmaceuticals | 121.72 Bn | 114.47 Bn | 2.59 Bn | 21.10% |
| 6 | Regeneron Pharmaceuticals | 68.28 Bn | 59.52 Bn | 3.31 Bn | 10.19% |
| 7 | Belite Bio | 61.40 Bn | 61.40 Bn | - | - |
| 8 | Argenx Se | 56.94 Bn | 56.94 Bn | 1.18 Bn | - |
| 9 | Revolution Medicines | 37.37 Bn | 37.37 Bn | - | -68.84% |
| 10 | Alnylam Pharmaceuticals | 36.08 Bn | 33.07 Bn | 959.66 Mn | 20.34% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 21.10% |
| Dec 31, 2025 | 19.51% |
| Sep 30, 2025 | 19.99% |
| Jun 30, 2025 | 20.31% |
| Mar 31, 2025 | -3.92% |
| Dec 31, 2024 | -1.24% |
| Sep 30, 2024 | -1.57% |
| Jun 30, 2024 | -1.89% |
| Mar 31, 2024 | 21.47% |
| Dec 31, 2023 | 20.51% |
| Sep 30, 2023 | 22.23% |
| Jun 30, 2023 | 24.31% |
| Mar 31, 2023 | 26.04% |
| Dec 31, 2022 | 29.33% |
| Sep 30, 2022 | 30.67% |
| Jun 30, 2022 | 33.00% |
| Mar 31, 2022 | 25.16% |
| Dec 31, 2021 | 25.56% |
| Sep 30, 2021 | 25.23% |
| Jun 30, 2021 | 21.95% |