Vertex Pharmaceuticals (VRTX) Return on Capital Employed (2010 - 2026)

Vertex Pharmaceuticals (VRTX) recorded quarterly Return on Capital Employed of 21.1% in Q1 2026, up 8.17% quarter-over-quarter from 19.51% in Q4 2025, and up 2503.0% on a YoY basis from 0.81% in Q1 2025.

Vertex Pharmaceuticals (VRTX) Return on Capital Employed (2010 - 2026) Analysis & Trends

Vertex Pharmaceuticals' Return on Capital Employed history runs 17 years deep, the most recent figure standing at 21.1% for Q1 2026.

  • In Q1 2026, Return on Capital Employed rose 2503.0% year-over-year to 21.1%; the TTM figure through Mar 2026 stood at 21.1% (up 2503.0% YoY), while the FY2025 annual figure was 20.63%, up 2185.0% from the prior year.
  • Return on Capital Employed was 21.1% for Q1 2026 at Vertex Pharmaceuticals, up from 19.51% in the prior quarter.
  • In the past five years, Return on Capital Employed ranged from a high of 33.0% in Q2 2022 to a low of 3.92% in Q1 2025.
  • Historically, Return on Capital Employed has averaged 17.94% across 5 years, with a median of 21.1% in 2026.
  • The sharpest annual moves came in 2024 and 2026: Return on Capital Employed sank 2620 bps in 2024, then jumped 2503 bps in 2026.
  • A 5-year view of Return on Capital Employed shows it stood at 29.33% in 2022, then plunged by 30 bps to 20.51% in 2023, then tumbled by 106 bps to 1.24% in 2024, then jumped by 1677 bps to 19.51% in 2025, then rose by 8 bps to 21.1% in 2026.
  • The last three Return on Capital Employed figures came in at 21.1% (Q1 2026), 19.51% (Q4 2025), and 19.99% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - 450.31%
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 51.73%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -107.40%
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 21.10%
9 Abivax 91.96 Bn 91.96 Bn - -50.43%
10 Regeneron Pharmaceuticals 63.43 Bn 54.67 Bn 3.31 Bn 10.19%

Historic Data

Download Data
DateValue
Mar 31, 2026 21.10%
Dec 31, 2025 19.51%
Sep 30, 2025 19.99%
Jun 30, 2025 20.31%
Mar 31, 2025 -3.92%
Dec 31, 2024 -1.24%
Sep 30, 2024 -1.57%
Jun 30, 2024 -1.89%
Mar 31, 2024 21.47%
Dec 31, 2023 20.51%
Sep 30, 2023 22.23%
Jun 30, 2023 24.31%
Mar 31, 2023 26.04%
Dec 31, 2022 29.33%
Sep 30, 2022 30.67%
Jun 30, 2022 33.00%
Mar 31, 2022 25.16%
Dec 31, 2021 25.56%
Sep 30, 2021 25.23%
Jun 30, 2021 21.95%