Vertex Pharmaceuticals (VRTX) Return on Capital Employed (2010 - 2026)
Vertex Pharmaceuticals (VRTX) recorded quarterly Return on Capital Employed of 21.1% in Q1 2026, up 8.17% quarter-over-quarter from 19.51% in Q4 2025, and up 2503.0% on a YoY basis from 0.81% in Q1 2025.
Vertex Pharmaceuticals (VRTX) Return on Capital Employed (2010 - 2026) Analysis & Trends
Vertex Pharmaceuticals' Return on Capital Employed history runs 17 years deep, the most recent figure standing at 21.1% for Q1 2026.
- In Q1 2026, Return on Capital Employed rose 2503.0% year-over-year to 21.1%; the TTM figure through Mar 2026 stood at 21.1% (up 2503.0% YoY), while the FY2025 annual figure was 20.63%, up 2185.0% from the prior year.
- Return on Capital Employed was 21.1% for Q1 2026 at Vertex Pharmaceuticals, up from 19.51% in the prior quarter.
- In the past five years, Return on Capital Employed ranged from a high of 33.0% in Q2 2022 to a low of 3.92% in Q1 2025.
- Historically, Return on Capital Employed has averaged 17.94% across 5 years, with a median of 21.1% in 2026.
- The sharpest annual moves came in 2024 and 2026: Return on Capital Employed sank 2620 bps in 2024, then jumped 2503 bps in 2026.
- A 5-year view of Return on Capital Employed shows it stood at 29.33% in 2022, then plunged by 30 bps to 20.51% in 2023, then tumbled by 106 bps to 1.24% in 2024, then jumped by 1677 bps to 19.51% in 2025, then rose by 8 bps to 21.1% in 2026.
- The last three Return on Capital Employed figures came in at 21.1% (Q1 2026), 19.51% (Q4 2025), and 19.99% (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROCE (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | 450.31% |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | 51.73% |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -107.40% |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 21.10% |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -50.43% |
| 10 | Regeneron Pharmaceuticals | 63.43 Bn | 54.67 Bn | 3.31 Bn | 10.19% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 21.10% |
| Dec 31, 2025 | 19.51% |
| Sep 30, 2025 | 19.99% |
| Jun 30, 2025 | 20.31% |
| Mar 31, 2025 | -3.92% |
| Dec 31, 2024 | -1.24% |
| Sep 30, 2024 | -1.57% |
| Jun 30, 2024 | -1.89% |
| Mar 31, 2024 | 21.47% |
| Dec 31, 2023 | 20.51% |
| Sep 30, 2023 | 22.23% |
| Jun 30, 2023 | 24.31% |
| Mar 31, 2023 | 26.04% |
| Dec 31, 2022 | 29.33% |
| Sep 30, 2022 | 30.67% |
| Jun 30, 2022 | 33.00% |
| Mar 31, 2022 | 25.16% |
| Dec 31, 2021 | 25.56% |
| Sep 30, 2021 | 25.23% |
| Jun 30, 2021 | 21.95% |