Alnylam Pharmaceuticals (ALNY) Return on Capital Employed (2010 - 2026)

Alnylam Pharmaceuticals (ALNY) reported Return on Capital Employed of 20.34% for Q1 2026, up 2400.0% on a YoY basis from 0.81% in Q1 2025, and up 39.58% quarter-over-quarter from 14.57% in Q4 2025.

Alnylam Pharmaceuticals (ALNY) Return on Capital Employed (2010 - 2026) Analysis & Trends

Alnylam Pharmaceuticals has reported Return on Capital Employed for 17 years, with the latest figure at 20.34% in Q1 2026.

  • For the quarter ending Q1 2026, Return on Capital Employed rose 2400.0% year-over-year to 20.34%; the trailing twelve-month figure through Mar 2026 stood at 20.34% (up 2400.0% YoY), and the FY2025 full-year result was 15.99%, up 2220.0% from the prior year.
  • Return on Capital Employed for Q1 2026 stood at 20.34%, up from 14.57% in the prior quarter.
  • The five-year high for Return on Capital Employed was 20.34% in Q1 2026, with the low at 31.68% in Q2 2023.
  • Historically, Return on Capital Employed has averaged 10.07% across 5 years, with a median of 6.52% in 2024.
  • Annual changes were most pronounced in 2024 — Return on Capital Employed surged 3526 bps — and 2025, when it plunged 942 bps.
  • Alnylam Pharmaceuticals' Return on Capital Employed stood at 28.31% in 2022, then jumped by 65 bps to 9.84% in 2023, then surged by 41 bps to 5.83% in 2024, then surged by 350 bps to 14.57% in 2025, then jumped by 40 bps to 20.34% in 2026.
  • The last three Return on Capital Employed figures came in at 20.34% (Q1 2026), 14.57% (Q4 2025), and 8.39% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - 450.31%
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 51.73%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -107.40%
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 21.10%
9 Abivax 91.96 Bn 91.96 Bn - -50.43%
10 Alnylam Pharmaceuticals 37.04 Bn 34.03 Bn 959.66 Mn 20.34%

Historic Data

Download Data
DateValue
Mar 31, 2026 20.34%
Dec 31, 2025 14.57%
Sep 30, 2025 8.39%
Jun 30, 2025 -5.83%
Mar 31, 2025 -3.66%
Dec 31, 2024 -5.83%
Sep 30, 2024 -6.52%
Jun 30, 2024 3.59%
Mar 31, 2024 -6.09%
Dec 31, 2023 -9.84%
Sep 30, 2023 -13.27%
Jun 30, 2023 -31.68%
Mar 31, 2023 -28.19%
Dec 31, 2022 -28.31%
Sep 30, 2022 -29.74%
Jun 30, 2022 -26.23%
Mar 31, 2022 -22.82%
Dec 31, 2021 -24.76%
Sep 30, 2021 -24.59%
Jun 30, 2021 -26.59%