Denali Therapeutics Inc. (DNLI) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

146,212,278Shares Outstanding

13,658,621Shares held by institutions

$245,582,006Value of institutional holdings

92.74%Institutional ownership %

1.19%Shares Changed QoQ

238No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

The institutional landscape for Denali Therapeutics Inc. (NASDAQ:DNLI) includes 238 filers as of the latest reporting cycle ending September 2025.

These investors collectively held 92.7% of the company's total shares outstanding in September 2025, down from 93.9% in June 2025.
On a quarter-over-quarter basis, institutional holdings shifted by 1.19%, with a year-over-year an increase of 10.19% in the count of filers.
Of these 238 institutional investors, 114 increased their holdings in Denali Therapeutics, while 76 of them reduced positions, and 48 investors maintained their exposure.
Collectively, institutional investors increased their stake in Denali Therapeutics to 135.60Mn shares as of September 2025, a change that is up by 1.60Mn shares quarter on quarter and up 8.82Mn shares year over year.
BlackRock, Inc.'s holding of 12.29Mn shares as of September 30, 2025 makes it the primary institutional investor in Denali Therapeutics, owning 8.41% of the stock.
Among the most significant buyers of Denali Therapeutics during September 2025 were Holocene Advisors, LP (2.73Mn), T. Rowe Price Investment Management, Inc. (2.39Mn), UBS Group AG (1.06Mn), STEMPOINT CAPITAL LP (1.03Mn), Foresite Capital Management VI LLC (1.00Mn).
Leading sellers of Denali Therapeutics stock in September 2025 included WELLINGTON MANAGEMENT GROUP LLP (5.61Mn), PRICE T ROWE ASSOCIATES INC /MD/ (2.01Mn), FMR LLC (1.20Mn), UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC (797.24K), MARSHALL WACE, LLP (618.22K).
The top 10 institutional holders of Denali Therapeutics for the quarter ending September 2025 included BlackRock, Inc. (12.29Mn), VANGUARD GROUP INC (11.99Mn), BAILLIE GIFFORD & CO (11.59Mn), FMR LLC (6.34Mn), T. Rowe Price Investment Management, Inc. (5.64Mn), UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC (5.47Mn), STATE STREET CORP (5.46Mn), Temasek Holdings (Private) Ltd (5.36Mn), Capital Research Global Investors (4.76Mn), PRICE T ROWE ASSOCIATES INC /MD/ (4.57Mn).

238 Institutional Holders

13,658,621 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
BlackRock, Inc.	30 Sep, 2025	12,289,307	236,281	1.96%	$178,440,737.00
VANGUARD GROUP INC	30 Sep, 2025	11,992,918	182,183	1.54%	$174,137,169.00
BAILLIE GIFFORD & CO	30 Sep, 2025	11,591,585	-363,738	-3.04%	$168,309,813.00
FMR LLC	30 Sep, 2025	6,340,316	-1,198,152	-15.89%	$92,061,393.00
T. Rowe Price Investment Management, Inc.	30 Sep, 2025	5,638,567	2,391,633	73.66%	$81,872.00
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	30 Sep, 2025	5,465,037	-797,240	-12.73%	$79,352,339.00
STATE STREET CORP	30 Sep, 2025	5,464,261	946,267	20.94%	$79,341,070.00
Temasek Holdings (Private) Ltd	30 Sep, 2025	5,355,832	0	0.00%	$77,766,681.00
Capital Research Global Investors	30 Sep, 2025	4,760,858	10,279	0.22%	$69,127,658.00
PRICE T ROWE ASSOCIATES INC /MD/	30 Sep, 2025	4,568,368	-2,013,927	-30.60%	$66,333.00
BAKER BROS. ADVISORS LP	30 Sep, 2025	3,731,695	0	0.00%	$54,184,211.00
ALLIANCEBERNSTEIN L.P.	30 Sep, 2025	3,520,414	383,274	12.22%	$51,116,411.00
GEODE CAPITAL MANAGEMENT, LLC	30 Sep, 2025	3,466,057	293,752	9.26%	$50,335,167.00
Crestline Management, LP	30 Sep, 2025	3,410,732	-450,000	-11.66%	$49,523,829.00
Holocene Advisors, LP	30 Sep, 2025	3,135,712	2,732,540	677.76%	$45,530,538.00
Point72 Asset Management, L.P.	30 Sep, 2025	2,519,535	305,588	13.80%	$36,583,650.00
DIMENSIONAL FUND ADVISORS LP	30 Sep, 2025	2,357,214	-55,714	-2.31%	$34,226,491.00
GOLDMAN SACHS GROUP INC	30 Sep, 2025	2,163,705	298,381	16.00%	$31,416,997.00
UBS Group AG	30 Sep, 2025	2,012,353	1,061,589	111.66%	$29,219,365.00
STEMPOINT CAPITAL LP	30 Sep, 2025	1,734,659	1,026,744	145.04%	$25,187,249.00

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Denali Therapeutics Inc. (DNLI) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

238 Institutional Holders

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