Denali Therapeutics (DNLI) Long-Term Investments (2017 - 2026)

Denali Therapeutics (DNLI) posted quarterly Long-Term Investments of $63.8 million for Q1 2026, down 72.95% year-over-year from $235.8 million in Q1 2025, and down 35.13% quarter-over-quarter from $98.3 million in Q4 2025.

Denali Therapeutics (DNLI) Long-Term Investments (2017 - 2026) Analysis & Trends

Denali Therapeutics (DNLI) has reported Long-Term Investments for 10 consecutive years, with $63.8 million the latest figure, recorded in Q1 2026.

  • In Q1 2026, Long-Term Investments fell 72.95% year-over-year to $63.8 million; the TTM figure through Mar 2026 stood at $63.8 million (down 72.95% YoY), while the FY2025 annual figure was $98.3 million, down 72.64% from the prior year.
  • Long-Term Investments slipped to $63.8 million in Q1 2026 per DNLI's latest filing, from $98.3 million in the prior quarter.
  • Across five years, Long-Term Investments topped out at $490.7 million in Q1 2024 and bottomed at $7.9 million in Q3 2023.
  • Historically, Long-Term Investments has averaged $216.7 million across 5 years, with a median of $167.1 million in 2025.
  • Annual changes were most pronounced in 2024 — Long-Term Investments jumped 5535.21% — and 2025, when it plunged 94.45%.
  • Denali Therapeutics' Long-Term Investments stood at $94.2 million in 2022, then sank by 91.61% to $7.9 million in 2023, then jumped by 4446.15% to $359.4 million in 2024, then slumped by 72.64% to $98.3 million in 2025, then tumbled by 35.13% to $63.8 million in 2026.
  • Business Quant data shows DNLI's Long-Term Investments at $63.8 million in Q1 2026, $98.3 million in Q4 2025, and $24.7 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Long-Term Investments (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 5.79 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 9.83 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn -
4 Revolution Medicines 43.64 Bn 43.64 Bn - -
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn -
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -
7 Royalty Pharma 33.72 Bn 35.84 Bn - 372.10 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 22.17 Mn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -
10 Denali Therapeutics 3.90 Bn 3.90 Bn 3.51 Mn 229.53 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 229.53 Mn
Mar 31, 2026 63.79 Mn
Dec 31, 2025 98.32 Mn
Sep 30, 2025 24.70 Mn
Jun 30, 2025 78.46 Mn
Mar 31, 2025 235.84 Mn
Dec 31, 2024 359.37 Mn
Sep 30, 2024 445.46 Mn
Jun 30, 2024 450.99 Mn
Mar 31, 2024 490.72 Mn
Sep 30, 2023 7.91 Mn
Jun 30, 2022 94.22 Mn
Mar 31, 2022 250.27 Mn
Dec 31, 2021 425.45 Mn
Sep 30, 2021 319.47 Mn
Jun 30, 2021 92.52 Mn
Mar 31, 2021 38.89 Mn
Dec 31, 2020 32.70 Mn
Sep 30, 2020 20.34 Mn
Jun 30, 2020 7.23 Mn