Denali Therapeutics (DNLI) EBT (2017 - 2026)
Denali Therapeutics' (DNLI) quarterly EBT came in at -$129.0 million in Q1 2026, up 5.05% year-on-year from -$122.8 million in Q1 2025, and up 1.84% on a QoQ basis from -$131.4 million in Q4 2025.
Denali Therapeutics (DNLI) EBT (2017 - 2026) Analysis & Trends
Denali Therapeutics (DNLI) has 10 years of EBT data on file, last reported at -$129.0 million in Q1 2026.
- On a quarterly basis, EBT rose 5.05% year-over-year to -$129.0 million in Q1 2026; TTM through Mar 2026 was -$562.5 million, a 20.88% decrease from a year earlier, with the FY2025 full-year figure at -$512.4 million, down 21.23% from the prior year.
- EBT for Q1 2026 stood at -$129.0 million, up from -$131.4 million in the prior quarter.
- Over the last five years, EBT for DNLI reached as high as $183.4 million in Q2 2023 and fell as low as -$172.2 million in Q2 2025.
- Historically, EBT has averaged -$94.7 million across 5 years, with a median of -$110.1 million in 2024.
- Across the five-year window, EBT jumped 412.05% in 2023 and tumbled 155.56% in 2024, its largest moves.
- Year by year, EBT stood at -$98.7 million in 2022, then dropped by 21.04% to -$119.4 million in 2023, then climbed by 1.57% to -$117.6 million in 2024, then decreased by 11.79% to -$131.4 million in 2025, then rose by 1.84% to -$129.0 million in 2026.
- Per Business Quant data, the three most recent EBT figures were -$129.0 million in Q1 2026, -$131.4 million in Q4 2025, and -$129.9 million in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBT (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 67,072.09 Bn | 67,072.09 Bn | - | -36.97 Mn |
| 2 | Nanobiotix | 1,894.61 Bn | 1,894.55 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | -15.31 Mn |
| 4 | BeOne Medicines | 471.64 Bn | 466.85 Bn | 1.35 Bn | 259.22 Mn |
| 5 | Vertex Pharmaceuticals | 121.72 Bn | 114.47 Bn | 2.59 Bn | 1.25 Bn |
| 6 | Regeneron Pharmaceuticals | 68.28 Bn | 59.52 Bn | 3.31 Bn | 831.20 Mn |
| 7 | Belite Bio | 61.40 Bn | 61.40 Bn | - | -26.94 Mn |
| 8 | Argenx Se | 56.94 Bn | 56.94 Bn | 1.18 Bn | 438.00 Mn |
| 9 | Revolution Medicines | 37.37 Bn | 37.37 Bn | - | -453.82 Mn |
| 10 | Denali Therapeutics | 4.33 Bn | 4.33 Bn | - | -129.01 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -129.01 Mn |
| Dec 31, 2025 | -131.43 Mn |
| Sep 30, 2025 | -129.88 Mn |
| Jun 30, 2025 | -172.23 Mn |
| Mar 31, 2025 | -135.87 Mn |
| Dec 31, 2024 | -117.57 Mn |
| Sep 30, 2024 | -110.08 Mn |
| Jun 30, 2024 | -101.88 Mn |
| Mar 31, 2024 | -104.60 Mn |
| Dec 31, 2023 | -119.44 Mn |
| Sep 30, 2023 | -99.35 Mn |
| Jun 30, 2023 | 183.38 Mn |
| Mar 31, 2023 | -112.78 Mn |
| Dec 31, 2022 | -98.68 Mn |
| Sep 30, 2022 | -103.30 Mn |
| Jun 30, 2022 | -58.77 Mn |
| Mar 31, 2022 | -69.12 Mn |
| Dec 31, 2021 | -75.84 Mn |
| Sep 30, 2021 | -84.59 Mn |
| Jun 30, 2021 | -60.69 Mn |