Growth Metrics

Axsome Therapeutics (AXSM) EBITDA Margin: 2022-2025

Historic EBITDA Margin for Axsome Therapeutics (AXSM) over the last 3 years, with Sep 2025 value amounting to -26.97%.

  • Axsome Therapeutics' EBITDA Margin rose 3281.00% to -26.97% in Q3 2025 from the same period last year, while for Sep 2025 it was -37.85%, marking a year-over-year increase of 5263.00%. This contributed to the annual value of -72.74% for FY2024, which is 1293.00% up from last year.
  • As of Q3 2025, Axsome Therapeutics' EBITDA Margin stood at -26.97%, which was down 10.20% from -24.47% recorded in Q2 2025.
  • Axsome Therapeutics' EBITDA Margin's 5-year high stood at -6.74% during Q1 2023, with a 5-year trough of -251.76% in Q3 2022.
  • For the 3-year period, Axsome Therapeutics' EBITDA Margin averaged around -71.77%, with its median value being -61.14% (2024).
  • Per our database at Business Quant, Axsome Therapeutics' EBITDA Margin soared by 14,428bps in 2023 and then crashed by 8,296bps in 2024.
  • Over the past 4 years, Axsome Therapeutics' EBITDA Margin (Quarterly) stood at -245.86% in 2022, then skyrocketed by 10,847bps to -137.39% in 2023, then skyrocketed by 7,625bps to -61.14% in 2024, then spiked by 3,281bps to -26.97% in 2025.
  • Its EBITDA Margin stands at -26.97% for Q3 2025, versus -24.47% for Q2 2025 and -46.91% for Q1 2025.