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Asset Utilization RatioAssets AverageDebt RatioDebt to EquityEBIT MarginEBITDA MarginEBT MarginEnterprise ValueEquity AverageEquity RatioFCF MarginGross MarginInventory AverageInvested CapitalNet MarginOperating MarginReturn on AssetsReturn on Capital EmployedReturn on EquityReturn on Invested CapitalReturn on Sales

Axsome Therapeutics (AXSM) Operating Margin (2022 - 2025)

Axsome Therapeutics' Operating Margin history spans 4 years, with the latest figure at 13.75% for Q4 2025.

  • For Q4 2025, Operating Margin rose 4739.0% year-over-year to 13.75%; the TTM value through Dec 2025 reached 26.12%, up 4662.0%, while the annual FY2025 figure was 26.12%, 4662.0% up from the prior year.
  • Operating Margin for Q4 2025 was 13.75% at Axsome Therapeutics, up from 26.97% in the prior quarter.
  • Across five years, Operating Margin topped out at 6.74% in Q1 2023 and bottomed at 444.23% in Q2 2022.
  • The 4-year median for Operating Margin is 75.34% (2024), against an average of 106.66%.
  • The largest annual shift saw Operating Margin skyrocketed 30492bps in 2023 before it plummeted -8296bps in 2024.
  • A 4-year view of Operating Margin shows it stood at 245.85% in 2022, then skyrocketed by 44bps to 137.39% in 2023, then surged by 55bps to 61.14% in 2024, then soared by 78bps to 13.75% in 2025.
  • Per Business Quant, the three most recent readings for AXSM's Operating Margin are 13.75% (Q4 2025), 26.97% (Q3 2025), and 24.47% (Q2 2025).