Growth Metrics

Axsome Therapeutics (AXSM) Debt to Equity (2016 - 2026)

Axsome Therapeutics recorded quarterly Debt to Equity of $2.36 in Q1 2026, up 63.32% quarter-over-quarter from $1.45 in Q4 2025, and down 33.82% year-over-year from $3.57 in Q1 2025.

Axsome Therapeutics' Debt to Equity history runs 11 years deep, the most recent figure standing at $2.36 for Q1 2026.

  • In Q1 2026, Debt to Equity fell 33.82% year-over-year to $2.36; the TTM figure through Mar 2026 stood at $2.36 (down 33.82% YoY), while the FY2025 annual figure was $1.45, down 54.35% from the prior year.
  • Debt to Equity came in at $2.36 for Q1 2026 at Axsome Therapeutics, up from $1.45 in the prior quarter.
  • In the past five years, Debt to Equity ranged from a high of $6.54 in Q2 2022 to a low of $0.64 in Q3 2022.
  • A 5-year average of $2.06 and a median of $1.73 in 2025 frame the typical range for Debt to Equity.
  • Across the five-year window, Debt to Equity soared 855.82% in 2022 and plunged 89.96% in 2023, its largest moves.
  • Axsome Therapeutics' Debt to Equity stood at $0.91 in 2022, then climbed by 5.66% to $0.97 in 2023, then jumped by 228.12% to $3.17 in 2024, then sank by 54.35% to $1.45 in 2025, then surged by 63.32% to $2.36 in 2026.
  • According to Business Quant data, Debt to Equity over the past three periods registered $2.36, $1.45, and $1.73 for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Debt/Equity (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn -
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 0.06
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn -
10 Axsome Therapeutics 11.82 Bn 11.51 Bn 176.48 Mn 2.36

Historic Data

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DateValue
Mar 31, 2026 2.36
Dec 31, 2025 1.45
Sep 30, 2025 1.73
Jun 30, 2025 2.57
Mar 31, 2025 3.57
Dec 31, 2024 3.17
Sep 30, 2024 2.03
Jun 30, 2024 1.81
Mar 31, 2024 1.28
Dec 31, 2023 0.97
Sep 30, 2023 0.68
Jun 30, 2023 0.66
Mar 31, 2023 1.37
Dec 31, 2022 0.91
Sep 30, 2022 0.64
Jun 30, 2022 6.54
Mar 31, 2022 3.36
Dec 31, 2021 3.14
Sep 30, 2021 1.15
Jun 30, 2021 0.68
Mar 31, 2021 0.50
Dec 31, 2020 0.42
Sep 30, 2020 0.36
Jun 30, 2020 0.13
Mar 31, 2020 0.13
Dec 31, 2019 0.11
Sep 30, 2019 2.90
Jun 30, 2019 0.81
Mar 31, 2019 1.11
Dec 31, 2018 7.37
Sep 30, 2018 10.40
Jun 30, 2018 1.21
Mar 31, 2018 0.73
Dec 31, 2017 0.59
Sep 30, 2017 0.60
Jun 30, 2017 0.44
Mar 31, 2017 0.34
Dec 31, 2016 0.45