Axsome Therapeutics (AXSM) Return on Capital Employed (2016 - 2026)
Axsome Therapeutics' (AXSM) quarterly Return on Capital Employed came in at 17.09% in Q1 2026, up 6272.0% year-on-year from 0.27% in Q1 2025, and down 33.53% quarter-over-quarter from 12.8% in Q4 2025.
Axsome Therapeutics (AXSM) Return on Capital Employed (2016 - 2026) Analysis & Trends
Axsome Therapeutics has disclosed Return on Capital Employed across 11 years of filings, most recently posting 17.09% for Q1 2026.
- Return on Capital Employed for Q1 2026 came in at 17.09%, up 6272.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 17.09% (up 6272.0% YoY), and the FY2025 annual result was 15.37%, up 6519.0% from the prior year.
- Return on Capital Employed came in at 17.09% for Q1 2026 at Axsome Therapeutics, down from 12.8% in the prior quarter.
- In the past five years, Return on Capital Employed ranged from a high of 12.8% in Q4 2025 to a low of 212.43% in Q1 2022.
- The 5-year median for Return on Capital Employed is 75.34% (2022), against an average of 76.5%.
- Across the five-year window, Return on Capital Employed plunged 15140 bps in 2022 and surged 15548 bps in 2023, its largest moves.
- Axsome Therapeutics' Return on Capital Employed stood at 75.34% in 2022, then surged by 32 bps to 50.87% in 2023, then slumped by 65 bps to 83.78% in 2024, then soared by 85 bps to 12.8% in 2025, then plunged by 34 bps to 17.09% in 2026.
- The last three Return on Capital Employed figures came in at 17.09% (Q1 2026), 12.8% (Q4 2025), and 72.2% (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROCE (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | 450.31% |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | 51.73% |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -107.40% |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 21.10% |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -50.43% |
| 10 | Axsome Therapeutics | 12.84 Bn | 12.54 Bn | 176.48 Mn | -17.09% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -17.09% |
| Dec 31, 2025 | -12.80% |
| Sep 30, 2025 | -72.20% |
| Jun 30, 2025 | -82.91% |
| Mar 31, 2025 | -79.80% |
| Dec 31, 2024 | -83.78% |
| Sep 30, 2024 | -85.38% |
| Jun 30, 2024 | -84.82% |
| Mar 31, 2024 | -69.21% |
| Dec 31, 2023 | -50.87% |
| Sep 30, 2023 | -39.36% |
| Jun 30, 2023 | -45.08% |
| Mar 31, 2023 | -56.95% |
| Dec 31, 2022 | -75.34% |
| Sep 30, 2022 | -76.45% |
| Jun 30, 2022 | -155.98% |
| Mar 31, 2022 | -212.43% |
| Dec 31, 2021 | -157.60% |
| Sep 30, 2021 | -113.89% |
| Jun 30, 2021 | -81.35% |