Axsome Therapeutics (AXSM) EBIT (2015 - 2026)

Axsome Therapeutics' (AXSM) quarterly EBIT came in at -$63.4 million in Q1 2026, down 11.19% year-on-year from -$71.3 million in Q1 2025, and down 162.53% quarter-over-quarter from $101.3 million in Q4 2025.

Axsome Therapeutics (AXSM) EBIT (2015 - 2026) Analysis & Trends

Axsome Therapeutics has disclosed EBIT across 12 years of filings, most recently posting -$63.4 million for Q1 2026.

  • EBIT for Q1 2026 came in at -$63.4 million, down 11.19% year-over-year; the trailing twelve-month figure through Mar 2026 was -$44.9 million (up 83.4% YoY), and the FY2025 annual result was -$38.5 million, up 86.29% from the prior year.
  • EBIT came in at -$63.4 million for Q1 2026 at Axsome Therapeutics, down from $101.3 million in the prior quarter.
  • In the past five years, EBIT ranged from a high of $101.3 million in Q4 2025 to a low of -$98.3 million in Q4 2023.
  • The 5-year median for EBIT is -$59.9 million (2022), against an average of -$46.7 million.
  • Across the five-year window, EBIT tumbled 955.46% in 2024 and soared 239.53% in 2025, its largest moves.
  • Axsome Therapeutics' EBIT stood at -$59.9 million in 2022, then plunged by 64.01% to -$98.3 million in 2023, then advanced by 26.11% to -$72.6 million in 2024, then jumped by 239.53% to $101.3 million in 2025, then plunged by 162.53% to -$63.4 million in 2026.
  • The last three EBIT figures came in at -$63.4 million (Q1 2026), $101.3 million (Q4 2025), and -$46.1 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBIT (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -32.68 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -2.97 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -19.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.82 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -15.76 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -1.51 Mn
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.14 Bn
9 Abivax 91.96 Bn 91.96 Bn - -65.83 Mn
10 Axsome Therapeutics 12.84 Bn 12.54 Bn 176.48 Mn -63.36 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -63.36 Mn
Dec 31, 2025 101.33 Mn
Sep 30, 2025 -46.11 Mn
Jun 30, 2025 -36.71 Mn
Mar 31, 2025 -56.98 Mn
Dec 31, 2024 -72.62 Mn
Sep 30, 2024 -62.62 Mn
Jun 30, 2024 -78.05 Mn
Mar 31, 2024 -67.28 Mn
Dec 31, 2023 -98.27 Mn
Sep 30, 2023 -62.12 Mn
Jun 30, 2023 -65.06 Mn
Mar 31, 2023 -6.37 Mn
Dec 31, 2022 -59.92 Mn
Sep 30, 2022 -42.41 Mn
Jun 30, 2022 -39.18 Mn
Mar 31, 2022 -38.29 Mn
Dec 31, 2021 -32.61 Mn
Sep 30, 2021 -33.41 Mn
Jun 30, 2021 -30.85 Mn