Axsome Therapeutics, Inc. (AXSM) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

0Shares Outstanding

3,409,443Shares held by institutions

$547,488,357Value of institutional holdings

76.41%Institutional ownership %

0.40%Shares Changed QoQ

341No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Axsome Therapeutics, Inc. (NASDAQ:AXSM) showed up in the 13F filings of 388 institutional investors as of December 2025.

These investors held 73.1% of outstanding shares in December 2025, down from 75.8% in September 2025.
They increased total shares held in Axsome Therapeutics by 6.06% from the prior quarter, while the number of investors in AXSM increased 34.72% year over year.
During the quarter, 218 of these 388 funds increased positions in AXSM, 121 reduced exposure, and 49 held steady.
Altogether, these fund groups held 36.56Mn shares in AXSM by December 2025, up by 2.09Mn shares quarter on quarter, and down 2.17Mn shares year over year.
As of December 31, 2025, the biggest holder of Axsome Therapeutics is VANGUARD GROUP INC at 4.16Mn shares, representing 8.33% of shares outstanding.
The most significant purchases of AXSM for the quarter ending December 2025 came from NOMURA ASSET MANAGEMENT INTERNATIONAL INC. (989.45K), NORGES BANK (495.46K), Rockefeller Capital Management L.P. (412.4K), Invesco Ltd. (282.94K), FMR LLC (253.74K).
The largest sales of AXSM for the quarter ending December 2025 came from BVF INC/IL (441.0K), Sofinnova Investments, Inc. (381.23K), PFM Health Sciences, LP (278.77K), ORBIMED ADVISORS LLC (278.68K), Jpmorgan Chase & Co (267.83K).
Per Business Quant data, the top 10 holders of Axsome Therapeutics for the quarter ending December 2025 are VANGUARD GROUP INC (4.16Mn), BlackRock, Inc. (3.91Mn), Invesco Ltd. (1.27Mn), WELLINGTON MANAGEMENT GROUP LLP (1.22Mn), FMR LLC (1.18Mn), Deep Track Capital, LP (1.15Mn), GEODE CAPITAL MANAGEMENT, LLC (1.01Mn), NOMURA ASSET MANAGEMENT INTERNATIONAL INC. (989.45K), State Street Corp (958.15K), RTW INVESTMENTS, LP (888.0K).

388 Institutional Holders

3,409,443 Total Shares Held

Rows:

Download Data

Owner Name	Date	Change (QoQ)	Change (%)	Value (USD)
BlackRock, Inc.	31 Dec, 2025	122,614	3.23%	$0.00
VANGUARD GROUP INC	31 Dec, 2025	-15,828	-0.38%	$0.00
Deep Track Capital, LP	31 Dec, 2025	250,000	27.78%	$0.00
Rockefeller Capital Management L.P.	31 Dec, 2025	419,857	7,318.41%	$0.00
Invesco Ltd.	31 Dec, 2025	282,937	28.56%	$0.00
Pictet Asset Management Holding SA	31 Dec, 2025	73,925	20.41%	$0.00
Barclays Plc	31 Dec, 2025	-56,999	-42.58%	$0.00
WELLINGTON MANAGEMENT GROUP LLP	31 Dec, 2025	-112,904	-8.46%	$0.00
FMR LLC	31 Dec, 2025	253,739	27.35%	$0.00
UBS Group AG	31 Dec, 2025	142,867	67.25%	$0.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	12,549	1.26%	$0.00
Nuveen, LLC	31 Dec, 2025	50,868	17.05%	$0.00
NOMURA ASSET MANAGEMENT INTERNATIONAL INC.	31 Dec, 2025	989,447	0.00%	$0.00
Qube Research & Technologies Ltd	31 Dec, 2025	-186	-0.06%	$0.00
State Street Corp	31 Dec, 2025	15,190	1.61%	$0.00
Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A.	31 Dec, 2025	-47,483	-14.55%	$0.00
RTW INVESTMENTS, LP	31 Dec, 2025	-230,882	-20.64%	$0.00
Man Group plc	31 Dec, 2025	-59,267	-20.59%	$0.00
ALETHEA CAPITAL MANAGEMENT, LLC	31 Dec, 2025	-2,173	-0.32%	$0.00
Vestal Point Capital, LP	31 Dec, 2025	60,000	40.00%	$0.00

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