Axsome Therapeutics (AXSM) Return on Sales (2022 - 2026)

Axsome Therapeutics' (AXSM) quarterly Return on Sales came in at 0.0% in Q1 2026, little changed year-on-year from 0.0% in Q1 2025, and down 131.42% quarter-over-quarter from 0.0% in Q4 2025.

Axsome Therapeutics (AXSM) Return on Sales (2022 - 2026) Analysis & Trends

Axsome Therapeutics has disclosed Return on Sales across 5 years of filings, most recently posting 0.0% for Q1 2026.

  • Return on Sales for Q1 2026 came in at 0.0%, changed 0.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 0.0% (up 1.0% YoY), and the FY2025 annual result was 0.0%, changed 0.0% from the prior year.
  • Return on Sales came in at 0.0% for Q1 2026 at Axsome Therapeutics, down from 0.0% in the prior quarter.
  • In the past five years, Return on Sales ranged from a high of 0.0% in Q1 2023 to a low of 1.5% in Q4 2024.
  • The 5-year median for Return on Sales is 0.01% (2024), against an average of 0.1%.
  • Across the five-year window, Return on Sales slumped 148 bps in 2024 and soared 150 bps in 2025, its largest moves.
  • Axsome Therapeutics' Return on Sales stood at 0.03% in 2022, then soared by 45 bps to 0.01% in 2023, then sank by 10763 bps to 1.5% in 2024, then jumped by 100 bps to 0.0% in 2025, then plunged by 131 bps to 0.0% in 2026.
  • The last three Return on Sales figures came in at 0.0% (Q1 2026), 0.0% (Q4 2025), and 0.0% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROS (Qtr)
1 Alterity Therapeutics 814,307.08 Bn 814,307.05 Bn - -
2 Belite Bio 55,320.00 Bn 55,320.00 Bn - -
3 Quantum Biopharma 17,149.72 Bn 17,149.72 Bn - -
4 Legend Biotech 3,590.00 Bn 3,589.71 Bn 242.10 Mn 0.00%
5 Akari Therapeutics 1,650.72 Bn 1,650.72 Bn - -
6 Evaxion A 1,522.09 Bn 1,522.07 Bn - 0.00%
7 Psyence Biomedical 229.39 Bn 229.38 Bn - -
8 Vertex Pharmaceuticals 113.09 Bn 105.85 Bn 2.59 Bn 0.00%
9 Abivax 90.15 Bn 90.15 Bn - -
10 Axsome Therapeutics 13.07 Bn 12.76 Bn 176.48 Mn 0.00%

Historic Data

Download Data
DateValue
Mar 31, 2026 0.00%
Dec 31, 2025 0.00%
Sep 30, 2025 0.00%
Jun 30, 2025 0.00%
Mar 31, 2025 0.00%
Dec 31, 2024 -1.50%
Sep 30, 2024 -0.01%
Jun 30, 2024 -0.01%
Mar 31, 2024 -0.01%
Dec 31, 2023 -0.01%
Sep 30, 2023 -0.01%
Jun 30, 2023 -0.01%
Mar 31, 2023 0.00%
Dec 31, 2022 -0.03%
Sep 30, 2022 -0.03%
Jun 30, 2022 -0.05%