Axsome Therapeutics (AXSM) EBT Margin (2022 - 2026)

Axsome Therapeutics (AXSM) reported EBT Margin of 33.76% for Q1 2026, up 1516.0% on a YoY basis from 2.09% in Q1 2025, and down 135.21% sequentially from 14.35% in Q4 2025.

Axsome Therapeutics (AXSM) EBT Margin (2022 - 2026) Analysis & Trends

Axsome Therapeutics (AXSM) has 5 years of EBT Margin data on file, last reported at 33.76% in Q1 2026.

  • For the quarter ending Q1 2026, EBT Margin rose 1516.0% year-over-year to 33.76%; the trailing twelve-month figure through Mar 2026 stood at 26.66% (up 6196.0% YoY), and the FY2025 full-year result was 28.77%, up 4567.0% from the prior year.
  • EBT Margin eased to 33.76% in Q1 2026, from 14.35% in the prior quarter.
  • In the past five years, EBT Margin ranged from a high of 9.13% in Q1 2023 to a low of 14965.4% in Q4 2024.
  • A 5-year average of 1047.2% and a median of 91.09% in 2024 frame the typical range for EBT Margin.
  • Across the five-year window, EBT Margin tumbled 1482703 bps in 2024 and surged 1495105 bps in 2025, its largest moves.
  • Tracing AXSM's EBT Margin over 5 years: stood at 251.29% in 2022, then surged by 45 bps to 138.37% in 2023, then plunged by 10716 bps to 14965.4% in 2024, then jumped by 100 bps to 14.35% in 2025, then tumbled by 135 bps to 33.76% in 2026.
  • Business Quant data shows AXSM's EBT Margin at 33.76% in Q1 2026, 14.35% in Q4 2025, and 27.62% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBT Margin (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 17.13%
4 NuCana 279.75 Bn 279.75 Bn - -
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 41.95%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 23.05%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 34.77%
9 Revolution Medicines 37.78 Bn 37.78 Bn - -
10 Axsome Therapeutics 12.37 Bn 12.06 Bn 176.48 Mn -33.76%

Historic Data

Download Data
DateValue
Mar 31, 2026 -33.76%
Dec 31, 2025 -14.35%
Sep 30, 2025 -27.62%
Jun 30, 2025 -32.61%
Mar 31, 2025 -48.91%
Dec 31, 2024 -14,965.40%
Sep 30, 2024 -61.67%
Jun 30, 2024 -91.03%
Mar 31, 2024 -91.14%
Dec 31, 2023 -138.37%
Sep 30, 2023 -108.80%
Jun 30, 2023 -145.15%
Mar 31, 2023 -9.13%
Dec 31, 2022 -251.29%
Sep 30, 2022 -266.08%
Jun 30, 2022 -469.82%