Axsome Therapeutics (AXSM) EBT Margin (2022 - 2026)

Axsome Therapeutics' (AXSM) quarterly EBT Margin came in at 33.76% in Q1 2026, up 1516.0% year-on-year from 2.09% in Q1 2025, and down 135.21% quarter-over-quarter from 14.35% in Q4 2025.

Axsome Therapeutics (AXSM) EBT Margin (2022 - 2026) Analysis & Trends

Axsome Therapeutics has disclosed EBT Margin across 5 years of filings, most recently posting 33.76% for Q1 2026.

  • EBT Margin for Q1 2026 came in at 33.76%, up 1516.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 26.66% (up 6196.0% YoY), and the FY2025 annual result was 28.77%, up 4567.0% from the prior year.
  • EBT Margin came in at 33.76% for Q1 2026 at Axsome Therapeutics, down from 14.35% in the prior quarter.
  • In the past five years, EBT Margin ranged from a high of 9.13% in Q1 2023 to a low of 14965.4% in Q4 2024.
  • The 5-year median for EBT Margin is 91.09% (2024), against an average of 1047.2%.
  • Across the five-year window, EBT Margin sank 1482703 bps in 2024 and surged 1495105 bps in 2025, its largest moves.
  • Axsome Therapeutics' EBT Margin stood at 251.29% in 2022, then soared by 45 bps to 138.37% in 2023, then tumbled by 10716 bps to 14965.4% in 2024, then surged by 100 bps to 14.35% in 2025, then slumped by 135 bps to 33.76% in 2026.
  • The last three EBT Margin figures came in at 33.76% (Q1 2026), 14.35% (Q4 2025), and 27.62% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBT Margin (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 6.40%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 41.95%
9 Abivax 91.96 Bn 91.96 Bn - -
10 Axsome Therapeutics 12.84 Bn 12.54 Bn 176.48 Mn -33.76%

Historic Data

Download Data
DateValue
Mar 31, 2026 -33.76%
Dec 31, 2025 -14.35%
Sep 30, 2025 -27.62%
Jun 30, 2025 -32.61%
Mar 31, 2025 -48.91%
Dec 31, 2024 -14,965.40%
Sep 30, 2024 -61.67%
Jun 30, 2024 -91.03%
Mar 31, 2024 -91.14%
Dec 31, 2023 -138.37%
Sep 30, 2023 -108.80%
Jun 30, 2023 -145.15%
Mar 31, 2023 -9.13%
Dec 31, 2022 -251.29%
Sep 30, 2022 -266.08%
Jun 30, 2022 -469.82%