Growth Metrics

Axsome Therapeutics (AXSM) EBT Margin (2022 - 2026)

Axsome Therapeutics recorded quarterly EBT Margin of 33.76% in Q1 2026, down 135.21% quarter-over-quarter from 14.35% in Q4 2025, and up 1516.0% year-over-year from 2.09% in Q1 2025.

Axsome Therapeutics' EBT Margin history runs 5 years deep, the most recent figure standing at 33.76% for Q1 2026.

  • In Q1 2026, EBT Margin rose 1516.0% year-over-year to 33.76%; the TTM figure through Mar 2026 stood at 26.66% (up 6196.0% YoY), while the FY2025 annual figure was 28.77%, up 4567.0% from the prior year.
  • EBT Margin came in at 33.76% for Q1 2026 at Axsome Therapeutics, down from 14.35% in the prior quarter.
  • In the past five years, EBT Margin ranged from a high of 9.13% in Q1 2023 to a low of 14965.4% in Q4 2024.
  • A 5-year average of 1047.2% and a median of 91.09% in 2024 frame the typical range for EBT Margin.
  • Across the five-year window, EBT Margin plunged 1482703 bps in 2024 and soared 1495105 bps in 2025, its largest moves.
  • Axsome Therapeutics' EBT Margin stood at 251.29% in 2022, then jumped by 45 bps to 138.37% in 2023, then slumped by 10716 bps to 14965.4% in 2024, then soared by 100 bps to 14.35% in 2025, then sank by 135 bps to 33.76% in 2026.
  • According to Business Quant data, EBT Margin over the past three periods registered 33.76%, 14.35%, and 27.62% for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBT Margin (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -6.40%
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 41.95%
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 23.05%
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 18.99%
10 Axsome Therapeutics 11.82 Bn 11.51 Bn 176.48 Mn -33.76%

Historic Data

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DateValue
Mar 31, 2026 -33.76%
Dec 31, 2025 -14.35%
Sep 30, 2025 -27.62%
Jun 30, 2025 -32.61%
Mar 31, 2025 -48.91%
Dec 31, 2024 -14,965.40%
Sep 30, 2024 -61.67%
Jun 30, 2024 -91.03%
Mar 31, 2024 -91.14%
Dec 31, 2023 -138.37%
Sep 30, 2023 -108.80%
Jun 30, 2023 -145.15%
Mar 31, 2023 -9.13%
Dec 31, 2022 -251.29%
Sep 30, 2022 -266.08%
Jun 30, 2022 -469.82%