Axsome Therapeutics (AXSM) Net Margin (2022 - 2026)
Axsome Therapeutics (AXSM) recorded Net Margin of -23.50% in Q2 2026, up 8.47 percentage points from -31.97% a year earlier and up 10.26 percentage points from the prior quarter.
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Analysis
Axsome Therapeutics (AXSM) Net Margin (2022 - 2026) Analysis & Trends
On a TTM basis, Axsome Therapeutics' Net Margin came in at -24.68% as of Jun 30, 2026, up 25.20 percentage points year-over-year; for FY2025, it came in at -28.69%, up 45.78 percentage points from FY2024.
- Annual Net Margin has increased for three straight years, with a three-year change of +345.30 percentage points (FY2022 to FY2025).
- Across earlier years, Net Margin came in at -74.47% in FY2024 (+13.94 pp), -88.41% in FY2023 (+285.58 pp) and -373.99% in FY2022.
- Quarterly Net Margin has ranged from -469.83% in Q2 2022 to -11.86% in Q1 2023 over the past five years.
- On a year-over-year basis, Net Margin has increased for nine consecutive quarters, with an average year-over-year change of +41.03 percentage points over the last eight quarters.
- Peak year-over-year performance for Net Margin in the last five years was a gain of 326.00 percentage points in Q2 2023, against a drop of 79.28 percentage points in Q1 2024 at the low end.
- Per Business Quant, the preceding three quarters came in at -33.76% (Q1 2026), -14.57% (Q4 2025) and -27.62% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 21.86% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 21.27% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | -8.04% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | 22.61% |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 18.81% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 23.62% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -134.51% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | -1.65% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 32.99% |
| 10 | Axsome Therapeutics | 10.14 Bn | 8.87 Bn | 204.81 Mn | -23.50% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -23.50% |
| Mar 31, 2026 | -33.76% |
| Dec 31, 2025 | -14.57% |
| Sep 30, 2025 | -27.62% |
| Jun 30, 2025 | -31.97% |
| Mar 31, 2025 | -48.91% |
| Dec 31, 2024 | -63.08% |
| Sep 30, 2024 | -61.67% |
| Jun 30, 2024 | -91.03% |
| Mar 31, 2024 | -91.14% |
| Dec 31, 2023 | -137.92% |
| Sep 30, 2023 | -107.62% |
| Jun 30, 2023 | -143.83% |
| Mar 31, 2023 | -11.86% |
| Dec 31, 2022 | -251.29% |
| Sep 30, 2022 | -266.08% |
| Jun 30, 2022 | -469.83% |
API Access
Axsome Therapeutics Net Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=net-margin&ticker=AXSM&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "net-margin", "ticker": "AXSM", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=net-margin&ticker=AXSM&period=max&api_key=YOUR_API_KEY");
const data = await res.json();