Axsome Therapeutics (AXSM) Net Margin (2022 - 2026)
Axsome Therapeutics recorded quarterly Net Margin of 33.76% in Q1 2026, down 131.42% quarter-over-quarter from 14.59% in Q4 2025, and up 1516.0% year-over-year from 2.09% in Q1 2025.
Axsome Therapeutics' Net Margin history runs 5 years deep, the most recent figure standing at 33.76% for Q1 2026.
- In Q1 2026, Net Margin rose 1516.0% year-over-year to 33.76%; the TTM figure through Mar 2026 stood at 26.59% (up 6207.0% YoY), while the FY2025 annual figure was 28.69%, up 4577.0% from the prior year.
- Net Margin came in at 33.76% for Q1 2026 at Axsome Therapeutics, down from 14.59% in the prior quarter.
- In the past five years, Net Margin ranged from a high of 11.88% in Q1 2023 to a low of 14982.4% in Q4 2024.
- A 5-year average of 1048.22% and a median of 91.09% in 2024 frame the typical range for Net Margin.
- Across the five-year window, Net Margin sank 1484448 bps in 2024 and soared 1496781 bps in 2025, its largest moves.
- Axsome Therapeutics' Net Margin stood at 251.29% in 2022, then soared by 45 bps to 137.92% in 2023, then plunged by 10763 bps to 14982.4% in 2024, then jumped by 100 bps to 14.59% in 2025, then tumbled by 131 bps to 33.76% in 2026.
- According to Business Quant data, Net Margin over the past three periods registered 33.76%, 14.59%, and 27.62% for Q1 2026, Q4 2025, and Q3 2025 respectively.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | - |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | - |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | 0.82% |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | - |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | - |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | 34.53% |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | - |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | 20.17% |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | 17.65% |
| 10 | Axsome Therapeutics | 11.82 Bn | 11.51 Bn | 176.48 Mn | -33.76% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -33.76% |
| Dec 31, 2025 | -14.59% |
| Sep 30, 2025 | -27.62% |
| Jun 30, 2025 | -31.95% |
| Mar 31, 2025 | -48.91% |
| Dec 31, 2024 | -14,982.40% |
| Sep 30, 2024 | -61.67% |
| Jun 30, 2024 | -91.03% |
| Mar 31, 2024 | -91.14% |
| Dec 31, 2023 | -137.92% |
| Sep 30, 2023 | -107.62% |
| Jun 30, 2023 | -143.87% |
| Mar 31, 2023 | -11.88% |
| Dec 31, 2022 | -251.29% |
| Sep 30, 2022 | -266.08% |
| Jun 30, 2022 | -469.82% |