Axsome Therapeutics (AXSM) Net Margin (2022 - 2026)
Axsome Therapeutics (AXSM) reported Net Margin of 33.76% for Q1 2026, up 1516.0% on a YoY basis from 2.09% in Q1 2025, and down 131.08% sequentially from 14.61% in Q4 2025.
Axsome Therapeutics (AXSM) Net Margin (2022 - 2026) Analysis & Trends
Axsome Therapeutics (AXSM) has 5 years of Net Margin data on file, last reported at 33.76% in Q1 2026.
- For the quarter ending Q1 2026, Net Margin rose 1516.0% year-over-year to 33.76%; the trailing twelve-month figure through Mar 2026 stood at 26.6% (up 6205.0% YoY), and the FY2025 full-year result was 28.69%, up 4577.0% from the prior year.
- Net Margin eased to 33.76% in Q1 2026, from 14.61% in the prior quarter.
- In the past five years, Net Margin ranged from a high of 11.88% in Q1 2023 to a low of 14982.4% in Q4 2024.
- A 5-year average of 1048.22% and a median of 91.09% in 2024 frame the typical range for Net Margin.
- Across the five-year window, Net Margin slumped 1484451 bps in 2024 and surged 1496779 bps in 2025, its largest moves.
- Tracing AXSM's Net Margin over 5 years: stood at 251.29% in 2022, then jumped by 45 bps to 137.89% in 2023, then slumped by 10765 bps to 14982.4% in 2024, then jumped by 100 bps to 14.61% in 2025, then plunged by 131 bps to 33.76% in 2026.
- Business Quant data shows AXSM's Net Margin at 33.76% in Q1 2026, 14.61% in Q4 2025, and 27.62% in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | - |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 15.02% |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | - |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 34.53% |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 20.17% |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | - |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | 30.33% |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | - |
| 10 | Axsome Therapeutics | 12.37 Bn | 12.06 Bn | 176.48 Mn | -33.76% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -33.76% |
| Dec 31, 2025 | -14.61% |
| Sep 30, 2025 | -27.62% |
| Jun 30, 2025 | -31.97% |
| Mar 31, 2025 | -48.91% |
| Dec 31, 2024 | -14,982.40% |
| Sep 30, 2024 | -61.67% |
| Jun 30, 2024 | -91.03% |
| Mar 31, 2024 | -91.14% |
| Dec 31, 2023 | -137.89% |
| Sep 30, 2023 | -107.62% |
| Jun 30, 2023 | -143.87% |
| Mar 31, 2023 | -11.88% |
| Dec 31, 2022 | -251.29% |
| Sep 30, 2022 | -266.08% |
| Jun 30, 2022 | -469.82% |