Axsome Therapeutics (AXSM) Net Margin (2022 - 2026)
Axsome Therapeutics' (AXSM) quarterly Net Margin came in at 33.76% in Q1 2026, up 1516.0% year-on-year from 2.09% in Q1 2025, and down 131.42% quarter-over-quarter from 14.59% in Q4 2025.
Axsome Therapeutics (AXSM) Net Margin (2022 - 2026) Analysis & Trends
Axsome Therapeutics has disclosed Net Margin across 5 years of filings, most recently posting 33.76% for Q1 2026.
- Net Margin for Q1 2026 came in at 33.76%, up 1516.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 26.59% (up 6207.0% YoY), and the FY2025 annual result was 28.69%, up 4577.0% from the prior year.
- Net Margin came in at 33.76% for Q1 2026 at Axsome Therapeutics, down from 14.59% in the prior quarter.
- In the past five years, Net Margin ranged from a high of 11.88% in Q1 2023 to a low of 14982.4% in Q4 2024.
- The 5-year median for Net Margin is 91.09% (2024), against an average of 1048.22%.
- Across the five-year window, Net Margin slumped 1484448 bps in 2024 and surged 1496781 bps in 2025, its largest moves.
- Axsome Therapeutics' Net Margin stood at 251.29% in 2022, then surged by 45 bps to 137.92% in 2023, then sank by 10763 bps to 14982.4% in 2024, then soared by 100 bps to 14.59% in 2025, then plunged by 131 bps to 33.76% in 2026.
- The last three Net Margin figures came in at 33.76% (Q1 2026), 14.59% (Q4 2025), and 27.62% (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | - |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | 0.82% |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | - |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 34.53% |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | - |
| 10 | Axsome Therapeutics | 12.84 Bn | 12.54 Bn | 176.48 Mn | -33.76% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -33.76% |
| Dec 31, 2025 | -14.59% |
| Sep 30, 2025 | -27.62% |
| Jun 30, 2025 | -31.95% |
| Mar 31, 2025 | -48.91% |
| Dec 31, 2024 | -14,982.40% |
| Sep 30, 2024 | -61.67% |
| Jun 30, 2024 | -91.03% |
| Mar 31, 2024 | -91.14% |
| Dec 31, 2023 | -137.92% |
| Sep 30, 2023 | -107.62% |
| Jun 30, 2023 | -143.87% |
| Mar 31, 2023 | -11.88% |
| Dec 31, 2022 | -251.29% |
| Sep 30, 2022 | -266.08% |
| Jun 30, 2022 | -469.82% |