Axsome Therapeutics AXSM
NASDAQ AXSM
$207.09 -1.26 (-0.60%)
As of: Sep 4, 2026 · 2:34 PM EDT

Axsome Therapeutics (AXSM) Gross Profit (2022 - 2026)

Axsome Therapeutics (AXSM) posted Gross Profit of $176.5 million for Q1 2026, down 3.92% sequentially from $183.7 million in Q4 2025, and up 58.03% YoY from $111.7 million in Q1 2025.

Analysis

Axsome Therapeutics (AXSM) Gross Profit (2022 - 2026) Analysis & Trends

Axsome Therapeutics has reported Gross Profit for 5 years, with the latest figure at $176.5 million in Q1 2026.

  • Quarterly Gross Profit rose 58.03% year-over-year to $176.5 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $655.8 million (up 136.68% YoY) and the FY2025 annual result came in at $591.0 million, up 67.72% from the prior year.
  • Gross Profit slipped to $176.5 million in Q1 2026 per AXSM's latest filing, from $183.7 million in the prior quarter.
  • Over five years, Gross Profit peaked at $183.7 million in Q4 2025 and troughed at -$10.0 million in Q4 2024.
  • A 5-year average of $80.7 million and a median of $73.9 million in 2024 frame the typical range for Gross Profit.
  • The sharpest annual moves came in 2024 and 2025: Gross Profit sank 115.61% in 2024, then jumped 1934.13% in 2025.
  • Over 5 years, Gross Profit stood at $22.1 million in 2022, then jumped by 190.54% to $64.2 million in 2023, then tumbled by 115.61% to -$10.0 million in 2024, then surged by 1934.13% to $183.7 million in 2025, then dropped by 3.92% to $176.5 million in 2026.
  • According to Business Quant data, Gross Profit over the past three periods registered $176.5 million, $183.7 million, and $159.1 million for Q1 2026, Q4 2025, and Q3 2025 respectively.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Vertex Pharmaceuticals 138.77 Bn 130.92 Bn 2.84 Bn
2 Regeneron Pharmaceuticals 85.51 Bn 77.52 Bn 3.93 Bn
3 Argenx Se 63.51 Bn 58.32 Bn 1.37 Bn
4 Moderna 58.20 Bn 53.06 Bn 52.00 Mn
5 Revolution Medicines 44.04 Bn 44.04 Bn -
6 BeOne Medicines 39.99 Bn 34.89 Bn 1.53 Bn
7 Alnylam Pharmaceuticals 35.45 Bn 32.14 Bn 992.69 Mn
8 Royalty Pharma 28.40 Bn 27.56 Bn -
9 Insmed 27.44 Bn 26.28 Bn 358.27 Mn
10 Axsome Therapeutics 10.73 Bn 10.41 Bn 204.81 Mn
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 204.81 Mn
Mar 31, 2026 176.48 Mn
Dec 31, 2025 183.67 Mn
Sep 30, 2025 159.08 Mn
Jun 30, 2025 136.59 Mn
Mar 31, 2025 111.67 Mn
Dec 31, 2024 -10.01 Mn
Sep 30, 2024 96.33 Mn
Jun 30, 2024 79.11 Mn
Mar 31, 2024 68.70 Mn
Dec 31, 2023 64.15 Mn
Sep 30, 2023 51.26 Mn
Jun 30, 2023 42.10 Mn
Mar 31, 2023 87.02 Mn
Dec 31, 2022 22.08 Mn
Sep 30, 2022 14.92 Mn
Jun 30, 2022 7.84 Mn