Axsome Therapeutics (AXSM) Gross Profit (2022 - 2026)
Axsome Therapeutics recorded quarterly Gross Profit of $176.5 million in Q1 2026, down 3.92% quarter-over-quarter from $183.7 million in Q4 2025, and up 58.03% year-over-year from $111.7 million in Q1 2025.
Axsome Therapeutics' Gross Profit history runs 5 years deep, the most recent figure standing at $176.5 million for Q1 2026.
- In Q1 2026, Gross Profit rose 58.03% year-over-year to $176.5 million; the TTM figure through Mar 2026 stood at $655.8 million (up 136.68% YoY), while the FY2025 annual figure was $591.0 million, up 67.72% from the prior year.
- Gross Profit came in at $176.5 million for Q1 2026 at Axsome Therapeutics, down from $183.7 million in the prior quarter.
- In the past five years, Gross Profit ranged from a high of $183.7 million in Q4 2025 to a low of -$10.0 million in Q4 2024.
- A 5-year average of $80.7 million and a median of $73.9 million in 2024 frame the typical range for Gross Profit.
- Across the five-year window, Gross Profit plunged 115.61% in 2024 and soared 1934.13% in 2025, its largest moves.
- Axsome Therapeutics' Gross Profit stood at $22.1 million in 2022, then soared by 190.54% to $64.2 million in 2023, then slumped by 115.61% to -$10.0 million in 2024, then jumped by 1934.13% to $183.7 million in 2025, then slipped by 3.92% to $176.5 million in 2026.
- According to Business Quant data, Gross Profit over the past three periods registered $176.5 million, $183.7 million, and $159.1 million for Q1 2026, Q4 2025, and Q3 2025 respectively.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) |
|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn |
| 10 | Axsome Therapeutics | 11.82 Bn | 11.51 Bn | 176.48 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 176.48 Mn |
| Mar 31, 2026 | 176.48 Mn |
| Dec 31, 2025 | 183.67 Mn |
| Dec 31, 2025 | 183.67 Mn |
| Sep 30, 2025 | 159.08 Mn |
| Sep 30, 2025 | 159.08 Mn |
| Jun 30, 2025 | 136.59 Mn |
| Jun 30, 2025 | 136.59 Mn |
| Mar 31, 2025 | 111.67 Mn |
| Mar 31, 2025 | 111.67 Mn |
| Dec 31, 2024 | -10.01 Mn |
| Dec 31, 2024 | -10.01 Mn |
| Sep 30, 2024 | 96.33 Mn |
| Sep 30, 2024 | 96.33 Mn |
| Jun 30, 2024 | 79.11 Mn |
| Jun 30, 2024 | 79.11 Mn |
| Mar 31, 2024 | 68.70 Mn |
| Mar 31, 2024 | 68.70 Mn |
| Dec 31, 2023 | 64.15 Mn |
| Dec 31, 2023 | 64.15 Mn |
| Sep 30, 2023 | 51.26 Mn |
| Sep 30, 2023 | 51.26 Mn |
| Jun 30, 2023 | 42.10 Mn |
| Jun 30, 2023 | 42.10 Mn |
| Mar 31, 2023 | 87.02 Mn |
| Mar 31, 2023 | 87.02 Mn |
| Dec 31, 2022 | 22.08 Mn |
| Dec 31, 2022 | 22.08 Mn |
| Sep 30, 2022 | 14.92 Mn |
| Sep 30, 2022 | 14.92 Mn |
| Jun 30, 2022 | 7.84 Mn |
| Jun 30, 2022 | 7.84 Mn |