Axsome Therapeutics (AXSM) Gross Profit (2022 - 2026)
Axsome Therapeutics' (AXSM) quarterly Gross Profit came in at $176.5 million in Q1 2026, up 58.03% year-on-year from $111.7 million in Q1 2025, and down 3.92% quarter-over-quarter from $183.7 million in Q4 2025.
Axsome Therapeutics (AXSM) Gross Profit (2022 - 2026) Analysis & Trends
Axsome Therapeutics has disclosed Gross Profit across 5 years of filings, most recently posting $176.5 million for Q1 2026.
- Gross Profit for Q1 2026 came in at $176.5 million, up 58.03% year-over-year; the trailing twelve-month figure through Mar 2026 was $655.8 million (up 136.68% YoY), and the FY2025 annual result was $591.0 million, up 67.72% from the prior year.
- Gross Profit came in at $176.5 million for Q1 2026 at Axsome Therapeutics, down from $183.7 million in the prior quarter.
- In the past five years, Gross Profit ranged from a high of $183.7 million in Q4 2025 to a low of -$10.0 million in Q4 2024.
- The 5-year median for Gross Profit is $73.9 million (2024), against an average of $80.7 million.
- Across the five-year window, Gross Profit sank 115.61% in 2024 and surged 1934.13% in 2025, its largest moves.
- Axsome Therapeutics' Gross Profit stood at $22.1 million in 2022, then surged by 190.54% to $64.2 million in 2023, then tumbled by 115.61% to -$10.0 million in 2024, then soared by 1934.13% to $183.7 million in 2025, then decreased by 3.92% to $176.5 million in 2026.
- The last three Gross Profit figures came in at $176.5 million (Q1 2026), $183.7 million (Q4 2025), and $159.1 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) |
|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - |
| 10 | Axsome Therapeutics | 12.84 Bn | 12.54 Bn | 176.48 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 176.48 Mn |
| Mar 31, 2026 | 176.48 Mn |
| Dec 31, 2025 | 183.67 Mn |
| Dec 31, 2025 | 183.67 Mn |
| Sep 30, 2025 | 159.08 Mn |
| Sep 30, 2025 | 159.08 Mn |
| Jun 30, 2025 | 136.59 Mn |
| Jun 30, 2025 | 136.59 Mn |
| Mar 31, 2025 | 111.67 Mn |
| Mar 31, 2025 | 111.67 Mn |
| Dec 31, 2024 | -10.01 Mn |
| Dec 31, 2024 | -10.01 Mn |
| Sep 30, 2024 | 96.33 Mn |
| Sep 30, 2024 | 96.33 Mn |
| Jun 30, 2024 | 79.11 Mn |
| Jun 30, 2024 | 79.11 Mn |
| Mar 31, 2024 | 68.70 Mn |
| Mar 31, 2024 | 68.70 Mn |
| Dec 31, 2023 | 64.15 Mn |
| Dec 31, 2023 | 64.15 Mn |