Axsome Therapeutics (AXSM) Gross Profit (2022 - 2026)
Axsome Therapeutics (AXSM) posted Gross Profit of $176.5 million for Q1 2026, down 3.92% sequentially from $183.7 million in Q4 2025, and up 58.03% YoY from $111.7 million in Q1 2025.
Analysis
Axsome Therapeutics (AXSM) Gross Profit (2022 - 2026) Analysis & Trends
Axsome Therapeutics has reported Gross Profit for 5 years, with the latest figure at $176.5 million in Q1 2026.
- Quarterly Gross Profit rose 58.03% year-over-year to $176.5 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $655.8 million (up 136.68% YoY) and the FY2025 annual result came in at $591.0 million, up 67.72% from the prior year.
- Gross Profit slipped to $176.5 million in Q1 2026 per AXSM's latest filing, from $183.7 million in the prior quarter.
- Over five years, Gross Profit peaked at $183.7 million in Q4 2025 and troughed at -$10.0 million in Q4 2024.
- A 5-year average of $80.7 million and a median of $73.9 million in 2024 frame the typical range for Gross Profit.
- The sharpest annual moves came in 2024 and 2025: Gross Profit sank 115.61% in 2024, then jumped 1934.13% in 2025.
- Over 5 years, Gross Profit stood at $22.1 million in 2022, then jumped by 190.54% to $64.2 million in 2023, then tumbled by 115.61% to -$10.0 million in 2024, then surged by 1934.13% to $183.7 million in 2025, then dropped by 3.92% to $176.5 million in 2026.
- According to Business Quant data, Gross Profit over the past three periods registered $176.5 million, $183.7 million, and $159.1 million for Q1 2026, Q4 2025, and Q3 2025 respectively.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) |
|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 138.77 Bn | 130.92 Bn | 2.84 Bn |
| 2 | Regeneron Pharmaceuticals | 85.51 Bn | 77.52 Bn | 3.93 Bn |
| 3 | Argenx Se | 63.51 Bn | 58.32 Bn | 1.37 Bn |
| 4 | Moderna | 58.20 Bn | 53.06 Bn | 52.00 Mn |
| 5 | Revolution Medicines | 44.04 Bn | 44.04 Bn | - |
| 6 | BeOne Medicines | 39.99 Bn | 34.89 Bn | 1.53 Bn |
| 7 | Alnylam Pharmaceuticals | 35.45 Bn | 32.14 Bn | 992.69 Mn |
| 8 | Royalty Pharma | 28.40 Bn | 27.56 Bn | - |
| 9 | Insmed | 27.44 Bn | 26.28 Bn | 358.27 Mn |
| 10 | Axsome Therapeutics | 10.73 Bn | 10.41 Bn | 204.81 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 204.81 Mn |
| Mar 31, 2026 | 176.48 Mn |
| Dec 31, 2025 | 183.67 Mn |
| Sep 30, 2025 | 159.08 Mn |
| Jun 30, 2025 | 136.59 Mn |
| Mar 31, 2025 | 111.67 Mn |
| Dec 31, 2024 | -10.01 Mn |
| Sep 30, 2024 | 96.33 Mn |
| Jun 30, 2024 | 79.11 Mn |
| Mar 31, 2024 | 68.70 Mn |
| Dec 31, 2023 | 64.15 Mn |
| Sep 30, 2023 | 51.26 Mn |
| Jun 30, 2023 | 42.10 Mn |
| Mar 31, 2023 | 87.02 Mn |
| Dec 31, 2022 | 22.08 Mn |
| Sep 30, 2022 | 14.92 Mn |
| Jun 30, 2022 | 7.84 Mn |