Axsome Therapeutics AXSM
NASDAQ AXSM
$206.82 -1.53 (-0.73%)
As of: Sep 4, 2026 · 3:59 PM EDT

Axsome Therapeutics (AXSM) Gross Margin (2022 - 2026)

Axsome Therapeutics (AXSM) posted Gross Margin of 92.3% for Q1 2026, down 1.51% sequentially from 93.71% in Q4 2025, and up 36.0% YoY from 67.87% in Q1 2025.

Analysis

Axsome Therapeutics (AXSM) Gross Margin (2022 - 2026) Analysis & Trends

Axsome Therapeutics has reported Gross Margin for 5 years, with the latest figure at 92.3% in Q1 2026.

  • Quarterly Gross Margin rose 36.0% year-over-year to 92.3% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 92.6% (up 432.0% YoY) and the FY2025 annual result came in at 92.56%, up 120.0% from the prior year.
  • Gross Margin eased to 92.3% in Q1 2026 per AXSM's latest filing, from 93.71% in the prior quarter.
  • Over five years, Gross Margin peaked at 93.71% in Q4 2025 and troughed at 2002.8% in Q4 2024.
  • A 5-year average of 39.87% and a median of 90.9% in 2025 frame the typical range for Gross Margin.
  • The sharpest annual moves came in 2024 and 2025: Gross Margin tumbled 209249 bps in 2024, then surged 209651 bps in 2025.
  • Over 5 years, Gross Margin stood at 90.6% in 2022, then fell by 1 bps to 89.69% in 2023, then tumbled by 2333 bps to 2002.8% in 2024, then jumped by 105 bps to 93.71% in 2025, then decreased by 2 bps to 92.3% in 2026.
  • According to Business Quant data, Gross Margin over the past three periods registered 92.3%, 93.71%, and 93.03% for Q1 2026, Q4 2025, and Q3 2025 respectively.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Gross Margin (Qtr)
1 Vertex Pharmaceuticals 138.47 Bn 130.62 Bn 2.84 Bn 85.33%
2 Regeneron Pharmaceuticals 85.18 Bn 77.19 Bn 3.93 Bn 91.59%
3 Argenx Se 63.38 Bn 58.19 Bn 1.37 Bn 90.43%
4 Moderna 58.09 Bn 52.95 Bn 52.00 Mn 35.86%
5 Revolution Medicines 44.33 Bn 44.33 Bn - -
6 BeOne Medicines 40.02 Bn 34.92 Bn 1.53 Bn 89.76%
7 Alnylam Pharmaceuticals 35.57 Bn 32.27 Bn 992.69 Mn 76.90%
8 Royalty Pharma 28.45 Bn 27.61 Bn - -
9 Insmed 27.48 Bn 26.32 Bn 358.27 Mn 84.20%
10 Axsome Therapeutics 10.75 Bn 10.43 Bn 204.81 Mn 93.79%
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 93.79%
Mar 31, 2026 92.30%
Dec 31, 2025 93.71%
Sep 30, 2025 93.03%
Jun 30, 2025 91.04%
Mar 31, 2025 91.94%
Dec 31, 2024 -2,002.80%
Sep 30, 2024 91.95%
Jun 30, 2024 90.76%
Mar 31, 2024 91.60%
Dec 31, 2023 89.69%
Sep 30, 2023 88.70%
Jun 30, 2023 90.15%
Mar 31, 2023 92.01%
Dec 31, 2022 90.60%
Sep 30, 2022 88.58%
Jun 30, 2022 88.85%