Axsome Therapeutics (AXSM) Gross Margin (2022 - 2026)
Axsome Therapeutics (AXSM) posted Gross Margin of 92.3% for Q1 2026, down 1.51% sequentially from 93.71% in Q4 2025, and up 36.0% YoY from 67.87% in Q1 2025.
Analysis
Axsome Therapeutics (AXSM) Gross Margin (2022 - 2026) Analysis & Trends
Axsome Therapeutics has reported Gross Margin for 5 years, with the latest figure at 92.3% in Q1 2026.
- Quarterly Gross Margin rose 36.0% year-over-year to 92.3% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 92.6% (up 432.0% YoY) and the FY2025 annual result came in at 92.56%, up 120.0% from the prior year.
- Gross Margin eased to 92.3% in Q1 2026 per AXSM's latest filing, from 93.71% in the prior quarter.
- Over five years, Gross Margin peaked at 93.71% in Q4 2025 and troughed at 2002.8% in Q4 2024.
- A 5-year average of 39.87% and a median of 90.9% in 2025 frame the typical range for Gross Margin.
- The sharpest annual moves came in 2024 and 2025: Gross Margin tumbled 209249 bps in 2024, then surged 209651 bps in 2025.
- Over 5 years, Gross Margin stood at 90.6% in 2022, then fell by 1 bps to 89.69% in 2023, then tumbled by 2333 bps to 2002.8% in 2024, then jumped by 105 bps to 93.71% in 2025, then decreased by 2 bps to 92.3% in 2026.
- According to Business Quant data, Gross Margin over the past three periods registered 92.3%, 93.71%, and 93.03% for Q1 2026, Q4 2025, and Q3 2025 respectively.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 138.47 Bn | 130.62 Bn | 2.84 Bn | 85.33% |
| 2 | Regeneron Pharmaceuticals | 85.18 Bn | 77.19 Bn | 3.93 Bn | 91.59% |
| 3 | Argenx Se | 63.38 Bn | 58.19 Bn | 1.37 Bn | 90.43% |
| 4 | Moderna | 58.09 Bn | 52.95 Bn | 52.00 Mn | 35.86% |
| 5 | Revolution Medicines | 44.33 Bn | 44.33 Bn | - | - |
| 6 | BeOne Medicines | 40.02 Bn | 34.92 Bn | 1.53 Bn | 89.76% |
| 7 | Alnylam Pharmaceuticals | 35.57 Bn | 32.27 Bn | 992.69 Mn | 76.90% |
| 8 | Royalty Pharma | 28.45 Bn | 27.61 Bn | - | - |
| 9 | Insmed | 27.48 Bn | 26.32 Bn | 358.27 Mn | 84.20% |
| 10 | Axsome Therapeutics | 10.75 Bn | 10.43 Bn | 204.81 Mn | 93.79% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 93.79% |
| Mar 31, 2026 | 92.30% |
| Dec 31, 2025 | 93.71% |
| Sep 30, 2025 | 93.03% |
| Jun 30, 2025 | 91.04% |
| Mar 31, 2025 | 91.94% |
| Dec 31, 2024 | -2,002.80% |
| Sep 30, 2024 | 91.95% |
| Jun 30, 2024 | 90.76% |
| Mar 31, 2024 | 91.60% |
| Dec 31, 2023 | 89.69% |
| Sep 30, 2023 | 88.70% |
| Jun 30, 2023 | 90.15% |
| Mar 31, 2023 | 92.01% |
| Dec 31, 2022 | 90.60% |
| Sep 30, 2022 | 88.58% |
| Jun 30, 2022 | 88.85% |