Axsome Therapeutics (AXSM) Gross Margin (2022 - 2026)
Axsome Therapeutics' (AXSM) quarterly Gross Margin came in at 92.3% in Q1 2026, up 36.0% year-on-year from 67.87% in Q1 2025, and down 1.51% quarter-over-quarter from 93.71% in Q4 2025.
Axsome Therapeutics (AXSM) Gross Margin (2022 - 2026) Analysis & Trends
Axsome Therapeutics has disclosed Gross Margin across 5 years of filings, most recently posting 92.3% for Q1 2026.
- Gross Margin for Q1 2026 came in at 92.3%, up 36.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 92.6% (up 432.0% YoY), and the FY2025 annual result was 92.56%, up 120.0% from the prior year.
- Gross Margin came in at 92.3% for Q1 2026 at Axsome Therapeutics, down from 93.71% in the prior quarter.
- In the past five years, Gross Margin ranged from a high of 93.71% in Q4 2025 to a low of 2002.8% in Q4 2024.
- The 5-year median for Gross Margin is 90.9% (2025), against an average of 39.87%.
- Across the five-year window, Gross Margin tumbled 209249 bps in 2024 and soared 209651 bps in 2025, its largest moves.
- Axsome Therapeutics' Gross Margin stood at 90.6% in 2022, then dropped by 1 bps to 89.69% in 2023, then tumbled by 2333 bps to 2002.8% in 2024, then surged by 105 bps to 93.71% in 2025, then fell by 2 bps to 92.3% in 2026.
- The last three Gross Margin figures came in at 92.3% (Q1 2026), 93.71% (Q4 2025), and 93.03% (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | - |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | 79.04% |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | - |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 86.85% |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | - |
| 10 | Axsome Therapeutics | 12.84 Bn | 12.54 Bn | 176.48 Mn | 92.30% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 92.30% |
| Dec 31, 2025 | 93.71% |
| Sep 30, 2025 | 93.03% |
| Jun 30, 2025 | 91.04% |
| Mar 31, 2025 | 91.94% |
| Dec 31, 2024 | -2,002.80% |
| Sep 30, 2024 | 91.95% |
| Jun 30, 2024 | 90.76% |
| Mar 31, 2024 | 91.60% |
| Dec 31, 2023 | 89.69% |
| Sep 30, 2023 | 88.70% |
| Jun 30, 2023 | 90.15% |
| Mar 31, 2023 | 92.01% |
| Dec 31, 2022 | 90.60% |
| Sep 30, 2022 | 88.58% |
| Jun 30, 2022 | 88.85% |