Axsome Therapeutics (AXSM) Gross Margin (2022 - 2026)

Axsome Therapeutics' (AXSM) quarterly Gross Margin came in at 92.3% in Q1 2026, up 36.0% year-on-year from 67.87% in Q1 2025, and down 1.51% quarter-over-quarter from 93.71% in Q4 2025.

Axsome Therapeutics (AXSM) Gross Margin (2022 - 2026) Analysis & Trends

Axsome Therapeutics has disclosed Gross Margin across 5 years of filings, most recently posting 92.3% for Q1 2026.

  • Gross Margin for Q1 2026 came in at 92.3%, up 36.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 92.6% (up 432.0% YoY), and the FY2025 annual result was 92.56%, up 120.0% from the prior year.
  • Gross Margin came in at 92.3% for Q1 2026 at Axsome Therapeutics, down from 93.71% in the prior quarter.
  • In the past five years, Gross Margin ranged from a high of 93.71% in Q4 2025 to a low of 2002.8% in Q4 2024.
  • The 5-year median for Gross Margin is 90.9% (2025), against an average of 39.87%.
  • Across the five-year window, Gross Margin tumbled 209249 bps in 2024 and soared 209651 bps in 2025, its largest moves.
  • Axsome Therapeutics' Gross Margin stood at 90.6% in 2022, then dropped by 1 bps to 89.69% in 2023, then tumbled by 2333 bps to 2002.8% in 2024, then surged by 105 bps to 93.71% in 2025, then fell by 2 bps to 92.3% in 2026.
  • The last three Gross Margin figures came in at 92.3% (Q1 2026), 93.71% (Q4 2025), and 93.03% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Gross Margin (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 79.04%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 86.85%
9 Abivax 91.96 Bn 91.96 Bn - -
10 Axsome Therapeutics 12.84 Bn 12.54 Bn 176.48 Mn 92.30%

Historic Data

Download Data
DateValue
Mar 31, 2026 92.30%
Dec 31, 2025 93.71%
Sep 30, 2025 93.03%
Jun 30, 2025 91.04%
Mar 31, 2025 91.94%
Dec 31, 2024 -2,002.80%
Sep 30, 2024 91.95%
Jun 30, 2024 90.76%
Mar 31, 2024 91.60%
Dec 31, 2023 89.69%
Sep 30, 2023 88.70%
Jun 30, 2023 90.15%
Mar 31, 2023 92.01%
Dec 31, 2022 90.60%
Sep 30, 2022 88.58%
Jun 30, 2022 88.85%