Axsome Therapeutics (AXSM) EBIT Margin (2022 - 2026)
Axsome Therapeutics' EBIT Margin came in at -22.73% for Q2 2026, up 1.73 percentage points from -24.47% a year earlier and up 10.40 percentage points from the prior quarter.
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Analysis
Axsome Therapeutics (AXSM) EBIT Margin (2022 - 2026) Analysis & Trends
Over the trailing twelve months to Jun 30, 2026, Axsome Therapeutics reported EBIT Margin of -23.96%, up 22.29 percentage points year-over-year; for FY2025, it was -26.12%, up 46.62 percentage points from FY2024.
- EBIT Margin has increased in each of the last three years, with a three-year change of +333.21 percentage points (FY2022 to FY2025).
- Going back by year, EBIT Margin was -72.74% in FY2024 (+12.93 pp), -85.67% in FY2023 (+273.66 pp) and -359.33% in FY2022.
- The five-year range for quarterly EBIT Margin is -444.23% (Q2 2022) to -6.74% (Q1 2023).
- Year-over-year, EBIT Margin has increased for nine consecutive quarters, with an average year-over-year change of +40.94 percentage points over the last eight quarters.
- The fastest year-over-year change in EBIT Margin over five years came in Q2 2023 (a gain of 304.92 percentage points), and the weakest in Q1 2024 (a drop of 82.96 percentage points).
- Business Quant data shows AXSM's EBIT Margin at -33.14% (Q1 2026), -13.75% (Q4 2025) and -26.97% (Q3 2025) in the three quarters before Q2 2026.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBIT Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 28.21% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 37.86% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | -3.52% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | 32.97% |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 20.57% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 34.95% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -133.21% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 28.37% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 37.40% |
| 10 | Axsome Therapeutics | 10.14 Bn | 8.87 Bn | 204.81 Mn | -22.73% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -22.73% |
| Mar 31, 2026 | -33.14% |
| Dec 31, 2025 | -13.75% |
| Sep 30, 2025 | -26.97% |
| Jun 30, 2025 | -24.47% |
| Mar 31, 2025 | -46.91% |
| Dec 31, 2024 | -61.14% |
| Sep 30, 2024 | -59.78% |
| Jun 30, 2024 | -89.54% |
| Mar 31, 2024 | -89.70% |
| Dec 31, 2023 | -137.39% |
| Sep 30, 2023 | -107.49% |
| Jun 30, 2023 | -139.31% |
| Mar 31, 2023 | -6.74% |
| Dec 31, 2022 | -245.86% |
| Sep 30, 2022 | -251.76% |
| Jun 30, 2022 | -444.23% |
API Access
Axsome Therapeutics EBIT Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=ebit-margin&ticker=AXSM&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "ebit-margin", "ticker": "AXSM", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=ebit-margin&ticker=AXSM&period=max&api_key=YOUR_API_KEY");
const data = await res.json();