Axsome Therapeutics (AXSM) Operating Expenses (2015 - 2026)
Axsome Therapeutics (AXSM) posted Operating Expenses of $254.6 million for Q1 2026, up 14.17% sequentially from $223.0 million in Q4 2025, and up 42.65% YoY from $178.4 million in Q1 2025.
Analysis
Axsome Therapeutics (AXSM) Operating Expenses (2015 - 2026) Analysis & Trends
Axsome Therapeutics has reported Operating Expenses for 12 years, with the latest figure at $254.6 million in Q1 2026.
- Quarterly Operating Expenses rose 42.65% year-over-year to $254.6 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $881.4 million (up 25.48% YoY) and the FY2025 annual result came in at $805.3 million, up 20.86% from the prior year.
- Operating Expenses improved to $254.6 million in Q1 2026 per AXSM's latest filing, from $223.0 million in the prior quarter.
- Over five years, Operating Expenses peaked at $254.6 million in Q1 2026 and troughed at $38.3 million in Q1 2022.
- A 5-year average of $144.6 million and a median of $165.2 million in 2024 frame the typical range for Operating Expenses.
- The sharpest annual moves came in 2023 and 2024: Operating Expenses jumped 163.65% in 2023, then climbed 12.71% in 2024.
- Over 5 years, Operating Expenses stood at $84.3 million in 2022, then soared by 101.45% to $169.8 million in 2023, then rose by 12.71% to $191.4 million in 2024, then advanced by 16.5% to $223.0 million in 2025, then increased by 14.17% to $254.6 million in 2026.
- According to Business Quant data, Operating Expenses over the past three periods registered $254.6 million, $223.0 million, and $217.1 million for Q1 2026, Q4 2025, and Q3 2025 respectively.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 138.47 Bn | 130.62 Bn | 2.84 Bn | 2.09 Bn |
| 2 | Regeneron Pharmaceuticals | 85.18 Bn | 77.19 Bn | 3.93 Bn | 3.00 Bn |
| 3 | Argenx Se | 63.38 Bn | 58.19 Bn | 1.37 Bn | -1.05 Bn |
| 4 | Moderna | 58.09 Bn | 52.95 Bn | 52.00 Mn | 960.00 Mn |
| 5 | Revolution Medicines | 44.33 Bn | 44.33 Bn | - | 505.13 Mn |
| 6 | BeOne Medicines | 40.02 Bn | 34.92 Bn | 1.53 Bn | 1.21 Bn |
| 7 | Alnylam Pharmaceuticals | 35.57 Bn | 32.27 Bn | 992.69 Mn | 1.06 Bn |
| 8 | Royalty Pharma | 28.45 Bn | 27.61 Bn | - | 541.02 Mn |
| 9 | Insmed | 27.48 Bn | 26.32 Bn | 358.27 Mn | 427.03 Mn |
| 10 | Axsome Therapeutics | 10.75 Bn | 10.43 Bn | 204.81 Mn | 268.02 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 268.02 Mn |
| Mar 31, 2026 | 254.56 Mn |
| Dec 31, 2025 | 222.96 Mn |
| Sep 30, 2025 | 217.10 Mn |
| Jun 30, 2025 | 186.76 Mn |
| Mar 31, 2025 | 178.45 Mn |
| Dec 31, 2024 | 191.38 Mn |
| Sep 30, 2024 | 167.39 Mn |
| Jun 30, 2024 | 165.21 Mn |
| Mar 31, 2024 | 142.27 Mn |
| Dec 31, 2023 | 169.80 Mn |
| Sep 30, 2023 | 119.91 Mn |
| Jun 30, 2023 | 111.76 Mn |
| Mar 31, 2023 | 100.95 Mn |
| Dec 31, 2022 | 84.29 Mn |
| Sep 30, 2022 | 59.26 Mn |
| Jun 30, 2022 | 48.00 Mn |
| Mar 31, 2022 | 38.29 Mn |
| Dec 31, 2021 | 32.61 Mn |
| Sep 30, 2021 | 33.41 Mn |