Axsome Therapeutics AXSM
NASDAQ AXSM
$206.82 -1.53 (-0.73%)
As of: Sep 4, 2026 · 3:59 PM EDT

Axsome Therapeutics (AXSM) Operating Expenses (2015 - 2026)

Axsome Therapeutics (AXSM) posted Operating Expenses of $254.6 million for Q1 2026, up 14.17% sequentially from $223.0 million in Q4 2025, and up 42.65% YoY from $178.4 million in Q1 2025.

Analysis

Axsome Therapeutics (AXSM) Operating Expenses (2015 - 2026) Analysis & Trends

Axsome Therapeutics has reported Operating Expenses for 12 years, with the latest figure at $254.6 million in Q1 2026.

  • Quarterly Operating Expenses rose 42.65% year-over-year to $254.6 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $881.4 million (up 25.48% YoY) and the FY2025 annual result came in at $805.3 million, up 20.86% from the prior year.
  • Operating Expenses improved to $254.6 million in Q1 2026 per AXSM's latest filing, from $223.0 million in the prior quarter.
  • Over five years, Operating Expenses peaked at $254.6 million in Q1 2026 and troughed at $38.3 million in Q1 2022.
  • A 5-year average of $144.6 million and a median of $165.2 million in 2024 frame the typical range for Operating Expenses.
  • The sharpest annual moves came in 2023 and 2024: Operating Expenses jumped 163.65% in 2023, then climbed 12.71% in 2024.
  • Over 5 years, Operating Expenses stood at $84.3 million in 2022, then soared by 101.45% to $169.8 million in 2023, then rose by 12.71% to $191.4 million in 2024, then advanced by 16.5% to $223.0 million in 2025, then increased by 14.17% to $254.6 million in 2026.
  • According to Business Quant data, Operating Expenses over the past three periods registered $254.6 million, $223.0 million, and $217.1 million for Q1 2026, Q4 2025, and Q3 2025 respectively.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Vertex Pharmaceuticals 138.47 Bn 130.62 Bn 2.84 Bn 2.09 Bn
2 Regeneron Pharmaceuticals 85.18 Bn 77.19 Bn 3.93 Bn 3.00 Bn
3 Argenx Se 63.38 Bn 58.19 Bn 1.37 Bn -1.05 Bn
4 Moderna 58.09 Bn 52.95 Bn 52.00 Mn 960.00 Mn
5 Revolution Medicines 44.33 Bn 44.33 Bn - 505.13 Mn
6 BeOne Medicines 40.02 Bn 34.92 Bn 1.53 Bn 1.21 Bn
7 Alnylam Pharmaceuticals 35.57 Bn 32.27 Bn 992.69 Mn 1.06 Bn
8 Royalty Pharma 28.45 Bn 27.61 Bn - 541.02 Mn
9 Insmed 27.48 Bn 26.32 Bn 358.27 Mn 427.03 Mn
10 Axsome Therapeutics 10.75 Bn 10.43 Bn 204.81 Mn 268.02 Mn
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 268.02 Mn
Mar 31, 2026 254.56 Mn
Dec 31, 2025 222.96 Mn
Sep 30, 2025 217.10 Mn
Jun 30, 2025 186.76 Mn
Mar 31, 2025 178.45 Mn
Dec 31, 2024 191.38 Mn
Sep 30, 2024 167.39 Mn
Jun 30, 2024 165.21 Mn
Mar 31, 2024 142.27 Mn
Dec 31, 2023 169.80 Mn
Sep 30, 2023 119.91 Mn
Jun 30, 2023 111.76 Mn
Mar 31, 2023 100.95 Mn
Dec 31, 2022 84.29 Mn
Sep 30, 2022 59.26 Mn
Jun 30, 2022 48.00 Mn
Mar 31, 2022 38.29 Mn
Dec 31, 2021 32.61 Mn
Sep 30, 2021 33.41 Mn