Growth Metrics

Axsome Therapeutics (AXSM) Operating Expenses (2015 - 2026)

Axsome Therapeutics recorded quarterly Operating Expenses of $254.6 million in Q1 2026, up 14.17% quarter-over-quarter from $223.0 million in Q4 2025, and up 42.65% year-over-year from $178.4 million in Q1 2025.

Axsome Therapeutics' Operating Expenses history runs 12 years deep, the most recent figure standing at $254.6 million for Q1 2026.

  • In Q1 2026, Operating Expenses rose 42.65% year-over-year to $254.6 million; the TTM figure through Mar 2026 stood at $881.4 million (up 25.48% YoY), while the FY2025 annual figure was $805.3 million, up 20.86% from the prior year.
  • Operating Expenses came in at $254.6 million for Q1 2026 at Axsome Therapeutics, up from $223.0 million in the prior quarter.
  • In the past five years, Operating Expenses ranged from a high of $254.6 million in Q1 2026 to a low of $38.3 million in Q1 2022.
  • A 5-year average of $144.6 million and a median of $165.2 million in 2024 frame the typical range for Operating Expenses.
  • Across the five-year window, Operating Expenses soared 163.65% in 2023 and advanced 12.71% in 2024, its largest moves.
  • Axsome Therapeutics' Operating Expenses stood at $84.3 million in 2022, then surged by 101.45% to $169.8 million in 2023, then increased by 12.71% to $191.4 million in 2024, then gained by 16.5% to $223.0 million in 2025, then grew by 14.17% to $254.6 million in 2026.
  • According to Business Quant data, Operating Expenses over the past three periods registered $254.6 million, $223.0 million, and $217.1 million for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - 2.97 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - 4.33 Mn
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -138.30 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - 15.76 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 1.85 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -3.82 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 2.96 Bn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 898.54 Mn
10 Axsome Therapeutics 11.82 Bn 11.51 Bn 176.48 Mn 254.56 Mn

Historic Data

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DateValue
Mar 31, 2026 254.56 Mn
Dec 31, 2025 222.96 Mn
Sep 30, 2025 217.10 Mn
Jun 30, 2025 186.76 Mn
Mar 31, 2025 178.45 Mn
Dec 31, 2024 191.38 Mn
Sep 30, 2024 167.39 Mn
Jun 30, 2024 165.21 Mn
Mar 31, 2024 142.27 Mn
Dec 31, 2023 169.80 Mn
Sep 30, 2023 119.91 Mn
Jun 30, 2023 111.76 Mn
Mar 31, 2023 100.95 Mn
Dec 31, 2022 84.29 Mn
Sep 30, 2022 59.26 Mn
Jun 30, 2022 48.00 Mn
Mar 31, 2022 38.29 Mn
Dec 31, 2021 32.61 Mn
Sep 30, 2021 33.41 Mn
Jun 30, 2021 30.85 Mn
Mar 31, 2021 27.84 Mn
Dec 31, 2020 27.74 Mn
Sep 30, 2020 21.13 Mn
Jun 30, 2020 17.78 Mn
Mar 31, 2020 32.49 Mn
Dec 31, 2019 24.43 Mn
Sep 30, 2019 18.95 Mn
Jun 30, 2019 13.45 Mn
Mar 31, 2019 10.42 Mn
Dec 31, 2018 9.45 Mn
Sep 30, 2018 8.24 Mn
Jun 30, 2018 7.99 Mn
Mar 31, 2018 7.16 Mn
Dec 31, 2017 6.44 Mn
Sep 30, 2017 6.30 Mn
Jun 30, 2017 6.75 Mn
Mar 31, 2017 7.67 Mn
Dec 31, 2016 7.63 Mn
Sep 30, 2016 7.21 Mn
Jun 30, 2016 6.83 Mn
Mar 31, 2016 5.88 Mn
Dec 31, 2015 3.15 Mn
Sep 30, 2015 2.02 Mn
Jun 30, 2015 2.08 Mn
Mar 31, 2015 1.93 Mn