Axsome Therapeutics (AXSM) Operating Expenses (2015 - 2026)
Axsome Therapeutics (AXSM) reported Operating Expenses of $254.6 million for Q1 2026, up 42.65% on a YoY basis from $178.4 million in Q1 2025, and up 14.17% sequentially from $223.0 million in Q4 2025.
Axsome Therapeutics (AXSM) Operating Expenses (2015 - 2026) Analysis & Trends
Axsome Therapeutics (AXSM) has 12 years of Operating Expenses data on file, last reported at $254.6 million in Q1 2026.
- For the quarter ending Q1 2026, Operating Expenses rose 42.65% year-over-year to $254.6 million; the trailing twelve-month figure through Mar 2026 stood at $881.4 million (up 25.48% YoY), and the FY2025 full-year result was $805.3 million, up 20.86% from the prior year.
- Operating Expenses improved to $254.6 million in Q1 2026, from $223.0 million in the prior quarter.
- In the past five years, Operating Expenses ranged from a high of $254.6 million in Q1 2026 to a low of $38.3 million in Q1 2022.
- A 5-year average of $144.6 million and a median of $165.2 million in 2024 frame the typical range for Operating Expenses.
- Across the five-year window, Operating Expenses surged 163.65% in 2023 and gained 12.71% in 2024, its largest moves.
- Tracing AXSM's Operating Expenses over 5 years: stood at $84.3 million in 2022, then soared by 101.45% to $169.8 million in 2023, then climbed by 12.71% to $191.4 million in 2024, then increased by 16.5% to $223.0 million in 2025, then advanced by 14.17% to $254.6 million in 2026.
- Business Quant data shows AXSM's Operating Expenses at $254.6 million in Q1 2026, $223.0 million in Q4 2025, and $217.1 million in Q3 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | -28.01 Mn |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 1.10 Bn |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | -3.78 Mn |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 1.85 Bn |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 2.96 Bn |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | 32.68 Mn |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | 2.89 Bn |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | 445.22 Mn |
| 10 | Axsome Therapeutics | 12.37 Bn | 12.06 Bn | 176.48 Mn | 254.56 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 254.56 Mn |
| Dec 31, 2025 | 222.96 Mn |
| Sep 30, 2025 | 217.10 Mn |
| Jun 30, 2025 | 186.76 Mn |
| Mar 31, 2025 | 178.45 Mn |
| Dec 31, 2024 | 191.38 Mn |
| Sep 30, 2024 | 167.39 Mn |
| Jun 30, 2024 | 165.21 Mn |
| Mar 31, 2024 | 142.27 Mn |
| Dec 31, 2023 | 169.80 Mn |
| Sep 30, 2023 | 119.91 Mn |
| Jun 30, 2023 | 111.76 Mn |
| Mar 31, 2023 | 100.95 Mn |
| Dec 31, 2022 | 84.29 Mn |
| Sep 30, 2022 | 59.26 Mn |
| Jun 30, 2022 | 48.00 Mn |
| Mar 31, 2022 | 38.29 Mn |
| Dec 31, 2021 | 32.61 Mn |
| Sep 30, 2021 | 33.41 Mn |
| Jun 30, 2021 | 30.85 Mn |