Axsome Therapeutics (AXSM) Operating Expenses (2015 - 2026)
Axsome Therapeutics' Operating Expenses came in at $268.02 million for Q2 2026, up 43.5% from $186.76 million a year earlier and up 5.3% from the prior quarter.
Axsome Therapeutics (AXSM) Operating Expenses (2015 - 2026) Analysis & Trends
Over the trailing twelve months to Jun 30, 2026, Axsome Therapeutics reported Operating Expenses of $962.64 million, up 33.0% year-over-year; for FY2025, it was $805.26 million, up 20.9% from FY2024.
- Operating Expenses has increased in each of the last eight years, with a five-year compound annual growth rate of 52.0% (FY2020 to FY2025).
- Going back by year, Operating Expenses was $666.26 million in FY2024 (+32.6%), $502.43 million in FY2023 (+118.6%), $229.84 million in FY2022 (+84.3%) and $124.71 million in FY2021 (+25.8%).
- The Q2 2026 figure represents the highest quarterly Operating Expenses in data going back to Q1 2015.
- Year-over-year, Operating Expenses has increased for 21 consecutive quarters, with growth averaging 27.9% over the last eight quarters.
- Across the past five years, year-over-year growth in Operating Expenses ran from 12.7% in Q4 2024 to 163.7% in Q1 2023.
- Business Quant data shows AXSM's Operating Expenses at $254.56 million (Q1 2026), $222.96 million (Q4 2025) and $217.1 million (Q3 2025) in the three quarters before Q2 2026.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 645.01 Bn | 563.54 Bn | 17.26 Bn | 10.12 Bn |
| 2 | AbbVie | 465.23 Bn | 438.39 Bn | 12.70 Bn | 10.56 Bn |
| 3 | Merck | 368.40 Bn | 322.83 Bn | 12.21 Bn | 12.80 Bn |
| 4 | Novartis Ag | 278.02 Bn | 233.89 Bn | 11.24 Bn | -6.09 Bn |
| 5 | Astrazeneca | 254.57 Bn | 228.13 Bn | 12.86 Bn | -9.70 Bn |
| 6 | Amgen | 229.02 Bn | 184.42 Bn | 7.24 Bn | 6.54 Bn |
| 7 | Gilead Sciences | 187.74 Bn | 161.85 Bn | 6.22 Bn | 18.20 Bn |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 6.68 Bn |
| 9 | Vertex Pharmaceuticals | 133.45 Bn | 105.45 Bn | 2.84 Bn | 2.09 Bn |
| 10 | Axsome Therapeutics | 9.74 Bn | 8.46 Bn | 204.81 Mn | 268.02 Mn |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 268.02 Mn |
| Mar 31, 2026 | 254.56 Mn |
| Dec 31, 2025 | 222.96 Mn |
| Sep 30, 2025 | 217.10 Mn |
| Jun 30, 2025 | 186.76 Mn |
| Mar 31, 2025 | 178.45 Mn |
| Dec 31, 2024 | 191.38 Mn |
| Sep 30, 2024 | 167.39 Mn |
| Jun 30, 2024 | 165.21 Mn |
| Mar 31, 2024 | 142.27 Mn |
| Dec 31, 2023 | 169.80 Mn |
| Sep 30, 2023 | 119.91 Mn |
| Jun 30, 2023 | 111.76 Mn |
| Mar 31, 2023 | 100.95 Mn |
| Dec 31, 2022 | 84.29 Mn |
| Sep 30, 2022 | 59.26 Mn |
| Jun 30, 2022 | 48.00 Mn |
| Mar 31, 2022 | 38.29 Mn |
| Dec 31, 2021 | 32.61 Mn |
| Sep 30, 2021 | 33.41 Mn |
Axsome Therapeutics Operating Expenses API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-expenses&ticker=AXSM&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-expenses", "ticker": "AXSM", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=operating-expenses&ticker=AXSM&period=max&api_key=YOUR_API_KEY");
const data = await res.json();