Axsome Therapeutics (AXSM) Operating Expenses (2015 - 2026)

Axsome Therapeutics (AXSM) reported Operating Expenses of $254.6 million for Q1 2026, up 42.65% on a YoY basis from $178.4 million in Q1 2025, and up 14.17% sequentially from $223.0 million in Q4 2025.

Axsome Therapeutics (AXSM) Operating Expenses (2015 - 2026) Analysis & Trends

Axsome Therapeutics (AXSM) has 12 years of Operating Expenses data on file, last reported at $254.6 million in Q1 2026.

  • For the quarter ending Q1 2026, Operating Expenses rose 42.65% year-over-year to $254.6 million; the trailing twelve-month figure through Mar 2026 stood at $881.4 million (up 25.48% YoY), and the FY2025 full-year result was $805.3 million, up 20.86% from the prior year.
  • Operating Expenses improved to $254.6 million in Q1 2026, from $223.0 million in the prior quarter.
  • In the past five years, Operating Expenses ranged from a high of $254.6 million in Q1 2026 to a low of $38.3 million in Q1 2022.
  • A 5-year average of $144.6 million and a median of $165.2 million in 2024 frame the typical range for Operating Expenses.
  • Across the five-year window, Operating Expenses surged 163.65% in 2023 and gained 12.71% in 2024, its largest moves.
  • Tracing AXSM's Operating Expenses over 5 years: stood at $84.3 million in 2022, then soared by 101.45% to $169.8 million in 2023, then climbed by 12.71% to $191.4 million in 2024, then increased by 16.5% to $223.0 million in 2025, then advanced by 14.17% to $254.6 million in 2026.
  • Business Quant data shows AXSM's Operating Expenses at $254.6 million in Q1 2026, $223.0 million in Q4 2025, and $217.1 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -28.01 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 1.10 Bn
4 NuCana 279.75 Bn 279.75 Bn - -3.78 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 1.85 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 2.96 Bn
7 Belite Bio 62.51 Bn 62.51 Bn - 32.68 Mn
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 2.89 Bn
9 Revolution Medicines 37.78 Bn 37.78 Bn - 445.22 Mn
10 Axsome Therapeutics 12.37 Bn 12.06 Bn 176.48 Mn 254.56 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 254.56 Mn
Dec 31, 2025 222.96 Mn
Sep 30, 2025 217.10 Mn
Jun 30, 2025 186.76 Mn
Mar 31, 2025 178.45 Mn
Dec 31, 2024 191.38 Mn
Sep 30, 2024 167.39 Mn
Jun 30, 2024 165.21 Mn
Mar 31, 2024 142.27 Mn
Dec 31, 2023 169.80 Mn
Sep 30, 2023 119.91 Mn
Jun 30, 2023 111.76 Mn
Mar 31, 2023 100.95 Mn
Dec 31, 2022 84.29 Mn
Sep 30, 2022 59.26 Mn
Jun 30, 2022 48.00 Mn
Mar 31, 2022 38.29 Mn
Dec 31, 2021 32.61 Mn
Sep 30, 2021 33.41 Mn
Jun 30, 2021 30.85 Mn