Axsome Therapeutics (AXSM) Operating Expenses (2015 - 2026)
Axsome Therapeutics recorded quarterly Operating Expenses of $254.6 million in Q1 2026, up 14.17% quarter-over-quarter from $223.0 million in Q4 2025, and up 42.65% year-over-year from $178.4 million in Q1 2025.
Axsome Therapeutics' Operating Expenses history runs 12 years deep, the most recent figure standing at $254.6 million for Q1 2026.
- In Q1 2026, Operating Expenses rose 42.65% year-over-year to $254.6 million; the TTM figure through Mar 2026 stood at $881.4 million (up 25.48% YoY), while the FY2025 annual figure was $805.3 million, up 20.86% from the prior year.
- Operating Expenses came in at $254.6 million for Q1 2026 at Axsome Therapeutics, up from $223.0 million in the prior quarter.
- In the past five years, Operating Expenses ranged from a high of $254.6 million in Q1 2026 to a low of $38.3 million in Q1 2022.
- A 5-year average of $144.6 million and a median of $165.2 million in 2024 frame the typical range for Operating Expenses.
- Across the five-year window, Operating Expenses soared 163.65% in 2023 and advanced 12.71% in 2024, its largest moves.
- Axsome Therapeutics' Operating Expenses stood at $84.3 million in 2022, then surged by 101.45% to $169.8 million in 2023, then increased by 12.71% to $191.4 million in 2024, then gained by 16.5% to $223.0 million in 2025, then grew by 14.17% to $254.6 million in 2026.
- According to Business Quant data, Operating Expenses over the past three periods registered $254.6 million, $223.0 million, and $217.1 million for Q1 2026, Q4 2025, and Q3 2025 respectively.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | 2.97 Mn |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | 4.33 Mn |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | -138.30 Mn |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | - |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | 15.76 Mn |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | 1.85 Bn |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | -3.82 Mn |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | 2.96 Bn |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | 898.54 Mn |
| 10 | Axsome Therapeutics | 11.82 Bn | 11.51 Bn | 176.48 Mn | 254.56 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 254.56 Mn |
| Dec 31, 2025 | 222.96 Mn |
| Sep 30, 2025 | 217.10 Mn |
| Jun 30, 2025 | 186.76 Mn |
| Mar 31, 2025 | 178.45 Mn |
| Dec 31, 2024 | 191.38 Mn |
| Sep 30, 2024 | 167.39 Mn |
| Jun 30, 2024 | 165.21 Mn |
| Mar 31, 2024 | 142.27 Mn |
| Dec 31, 2023 | 169.80 Mn |
| Sep 30, 2023 | 119.91 Mn |
| Jun 30, 2023 | 111.76 Mn |
| Mar 31, 2023 | 100.95 Mn |
| Dec 31, 2022 | 84.29 Mn |
| Sep 30, 2022 | 59.26 Mn |
| Jun 30, 2022 | 48.00 Mn |
| Mar 31, 2022 | 38.29 Mn |
| Dec 31, 2021 | 32.61 Mn |
| Sep 30, 2021 | 33.41 Mn |
| Jun 30, 2021 | 30.85 Mn |
| Mar 31, 2021 | 27.84 Mn |
| Dec 31, 2020 | 27.74 Mn |
| Sep 30, 2020 | 21.13 Mn |
| Jun 30, 2020 | 17.78 Mn |
| Mar 31, 2020 | 32.49 Mn |
| Dec 31, 2019 | 24.43 Mn |
| Sep 30, 2019 | 18.95 Mn |
| Jun 30, 2019 | 13.45 Mn |
| Mar 31, 2019 | 10.42 Mn |
| Dec 31, 2018 | 9.45 Mn |
| Sep 30, 2018 | 8.24 Mn |
| Jun 30, 2018 | 7.99 Mn |
| Mar 31, 2018 | 7.16 Mn |
| Dec 31, 2017 | 6.44 Mn |
| Sep 30, 2017 | 6.30 Mn |
| Jun 30, 2017 | 6.75 Mn |
| Mar 31, 2017 | 7.67 Mn |
| Dec 31, 2016 | 7.63 Mn |
| Sep 30, 2016 | 7.21 Mn |
| Jun 30, 2016 | 6.83 Mn |
| Mar 31, 2016 | 5.88 Mn |
| Dec 31, 2015 | 3.15 Mn |
| Sep 30, 2015 | 2.02 Mn |
| Jun 30, 2015 | 2.08 Mn |
| Mar 31, 2015 | 1.93 Mn |