Axsome Therapeutics (AXSM) EBITDA (2015 - 2026)

Axsome Therapeutics (AXSM) reported EBITDA of -$63.4 million for Q1 2026, down 11.19% on a YoY basis from -$71.3 million in Q1 2025, and down 135.03% sequentially from -$27.0 million in Q4 2025.

Axsome Therapeutics (AXSM) EBITDA (2015 - 2026) Analysis & Trends

Axsome Therapeutics (AXSM) has 12 years of EBITDA data on file, last reported at -$63.4 million in Q1 2026.

  • For the quarter ending Q1 2026, EBITDA fell 11.19% year-over-year to -$63.4 million; the trailing twelve-month figure through Mar 2026 stood at -$173.1 million (up 35.94% YoY), and the FY2025 full-year result was -$166.8 million, up 40.56% from the prior year.
  • EBITDA retreated to -$63.4 million in Q1 2026, from -$27.0 million in the prior quarter.
  • In the past five years, EBITDA ranged from a high of -$6.4 million in Q1 2023 to a low of -$98.3 million in Q4 2023.
  • A 5-year average of -$54.3 million and a median of -$59.9 million in 2022 frame the typical range for EBITDA.
  • Across the five-year window, EBITDA soared 83.35% in 2023 and sank 955.46% in 2024, its largest moves.
  • Tracing AXSM's EBITDA over 5 years: stood at -$59.9 million in 2022, then sank by 64.01% to -$98.3 million in 2023, then gained by 26.11% to -$72.6 million in 2024, then soared by 62.88% to -$27.0 million in 2025, then tumbled by 135.03% to -$63.4 million in 2026.
  • Business Quant data shows AXSM's EBITDA at -$63.4 million in Q1 2026, -$27.0 million in Q4 2025, and -$46.1 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -27.75 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 249.90 Mn
4 NuCana 279.75 Bn 279.75 Bn - -3.72 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 1.14 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 642.90 Mn
7 Belite Bio 62.51 Bn 62.51 Bn - -32.68 Mn
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 493.00 Mn
9 Revolution Medicines 37.78 Bn 37.78 Bn - -445.22 Mn
10 Axsome Therapeutics 12.37 Bn 12.06 Bn 176.48 Mn -63.36 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -63.36 Mn
Dec 31, 2025 -26.96 Mn
Sep 30, 2025 -46.11 Mn
Jun 30, 2025 -36.71 Mn
Mar 31, 2025 -56.98 Mn
Dec 31, 2024 -72.62 Mn
Sep 30, 2024 -62.62 Mn
Jun 30, 2024 -78.05 Mn
Mar 31, 2024 -67.28 Mn
Dec 31, 2023 -98.27 Mn
Sep 30, 2023 -62.12 Mn
Jun 30, 2023 -65.06 Mn
Mar 31, 2023 -6.37 Mn
Dec 31, 2022 -59.92 Mn
Sep 30, 2022 -42.41 Mn
Jun 30, 2022 -39.18 Mn
Mar 31, 2022 -38.29 Mn
Dec 31, 2021 -32.61 Mn
Sep 30, 2021 -33.41 Mn
Jun 30, 2021 -30.85 Mn