Lyell Immunopharma (LYEL) EBITDA Margin (2020 - 2026)

Lyell Immunopharma recorded quarterly EBITDA Margin of 1220200.0% in Q1 2026, up 47.96% quarter-over-quarter from 2344700.0% in Q4 2025, and down 47265714.0% year-over-year from N/an in Q1 2025.

Lyell Immunopharma's EBITDA Margin history runs 7 years deep, the most recent figure standing at 1220200.0% for Q1 2026.

  • In Q1 2026, EBITDA Margin fell 47265714.0% year-over-year to 1220200.0%; the TTM figure through Mar 2026 stood at 795396.77% (down 28161216.0% YoY), while the FY2025 annual figure was 762491.67%, down 20083757.0% from the prior year.
  • EBITDA Margin came in at 1220200.0% for Q1 2026 at Lyell Immunopharma, up from 2344700.0% in the prior quarter.
  • In the past five years, EBITDA Margin ranged from a high of 12.4% in Q4 2022 to a low of 2396633.33% in Q3 2022.
  • A 5-year average of 747221.25% and a median of 352323.08% in 2024 frame the typical range for EBITDA Margin.
  • Across the five-year window, EBITDA Margin plunged 239485428 bps in 2022 and surged 219801333 bps in 2023, its largest moves.
  • Lyell Immunopharma's EBITDA Margin stood at 12.4% in 2022, then slumped by 3215894 bps to 398792.31% in 2023, then tumbled by 339 bps to 1749127.27% in 2024, then slumped by 34 bps to 2344700.0% in 2025, then surged by 48 bps to 1220200.0% in 2026.
  • According to Business Quant data, EBITDA Margin over the past three periods registered 1220200.0%, 2344700.0%, and 258013.33% for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA Margin (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn - -
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn - -
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn -6.43%
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn - -
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn - -
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn 38.10%
7 Evaxion A 64.16 Bn 64.14 Bn - -
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn 18.35%
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn 17.24%
10 Lyell Immunopharma 379.11 Mn 379.11 Mn - -1,220,200.00%

Historic Data

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DateValue
Mar 31, 2026 -1,220,200.00%
Dec 31, 2025 -2,344,700.00%
Sep 30, 2025 -258,013.33%
Jun 30, 2025 -534,812.50%
Mar 31, 2025 -747,542.86%
Dec 31, 2024 -1,749,127.27%
Sep 30, 2024 -127,723.53%
Jun 30, 2024 -352,323.08%
Mar 31, 2024 -2,032,566.67%
Dec 31, 2023 -398,792.31%
Sep 30, 2023 -198,620.00%
Jun 30, 2023 -231,074.07%
Mar 31, 2023 -97,290.77%
Dec 31, 2022 -12.40%
Sep 30, 2022 -2,396,633.33%
Jun 30, 2022 -106.53%
Mar 31, 2022 -13,222.60%
Dec 31, 2021 -3,021.40%
Sep 30, 2021 -1,779.06%
Jun 30, 2021 -2,385.27%
Mar 31, 2021 -2,255.05%
Dec 31, 2020 -1,695.24%
Sep 30, 2020 -3,394.11%
Jun 30, 2020 -3,224.86%