Lyell Immunopharma (LYEL) Research & Development (2020 - 2026)

Lyell Immunopharma (LYEL) posted Research & Development of $36.6 million for Q1 2026, down 29.88% sequentially from $52.2 million in Q4 2025, and down 15.75% YoY from $43.4 million in Q1 2025.

Lyell Immunopharma (LYEL) Research & Development (2020 - 2026) Analysis & Trends

Lyell Immunopharma has reported Research & Development for 7 years, with the latest figure at $36.6 million in Q1 2026.

  • Quarterly Research & Development fell 15.75% year-over-year to $36.6 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $151.8 million (down 11.66% YoY) and the FY2025 annual result came in at $158.7 million, down 7.53% from the prior year.
  • Research & Development retreated to $36.6 million in Q1 2026 per LYEL's latest filing, from $52.2 million in the prior quarter.
  • Over five years, Research & Development peaked at $52.2 million in Q4 2025 and troughed at $28.2 million in Q3 2025.
  • A 5-year average of $41.7 million and a median of $43.2 million in 2024 frame the typical range for Research & Development.
  • The sharpest annual moves came in 2022 and 2025: Research & Development surged 97.21% in 2022, then slipped 28.68% in 2025.
  • Over 5 years, Research & Development stood at $38.0 million in 2022, then advanced by 23.57% to $47.0 million in 2023, then advanced by 3.56% to $48.7 million in 2024, then grew by 7.26% to $52.2 million in 2025, then decreased by 29.88% to $36.6 million in 2026.
  • According to Business Quant data, Research & Development over the past three periods registered $36.6 million, $52.2 million, and $28.2 million for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) R&D (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 993.80 Mn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 1.63 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 1.37 Bn
4 Revolution Medicines 43.64 Bn 43.64 Bn - 394.92 Mn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 612.28 Mn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn 1,146.05
7 Royalty Pharma 33.72 Bn 35.84 Bn - 97.90 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 413.13 Mn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn 210.03 Mn
10 Lyell Immunopharma 326.39 Mn 326.39 Mn - 39.52 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 39.52 Mn
Mar 31, 2026 36.60 Mn
Dec 31, 2025 52.20 Mn
Sep 30, 2025 28.17 Mn
Jun 30, 2025 34.86 Mn
Mar 31, 2025 43.45 Mn
Dec 31, 2024 48.67 Mn
Sep 30, 2024 39.50 Mn
Jun 30, 2024 40.26 Mn
Mar 31, 2024 43.17 Mn
Dec 31, 2023 47.00 Mn
Sep 30, 2023 43.85 Mn
Jun 30, 2023 47.47 Mn
Mar 31, 2023 44.63 Mn
Dec 31, 2022 38.03 Mn
Sep 30, 2022 41.61 Mn
Jun 30, 2022 43.72 Mn
Mar 31, 2022 35.83 Mn
Dec 31, 2021 19.29 Mn
Sep 30, 2021 31.43 Mn