Lyell Immunopharma (LYEL) Net Margin (2020 - 2026)

Lyell Immunopharma (LYEL) posted Net Margin of 5160800.0% for Q1 2026, down 114.0% sequentially from 2411550.0% in Q4 2025, and down 331961429.0% YoY from N/an in Q1 2025.

Lyell Immunopharma (LYEL) Net Margin (2020 - 2026) Analysis & Trends

Lyell Immunopharma has reported Net Margin for 7 years, with the latest figure at 5160800.0% in Q1 2026.

  • Quarterly Net Margin fell 331961429.0% year-over-year to 5160800.0% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 1501754.84% (down 4971484.0% YoY) and the FY2025 annual result came in at 795952.78%, up 38078493.0% from the prior year.
  • Net Margin declined to 5160800.0% in Q1 2026 per LYEL's latest filing, from 2411550.0% in the prior quarter.
  • Over five years, Net Margin peaked at 28.02% in Q4 2022 and troughed at 6279266.67% in Q3 2022.
  • A 5-year average of 1759631.73% and a median of 995992.31% in 2024 frame the typical range for Net Margin.
  • The sharpest annual moves came in 2022 and 2023: Net Margin sank 627706536 bps in 2022, then surged 599906667 bps in 2023.
  • Over 5 years, Net Margin stood at 28.02% in 2022, then sank by 8423430 bps to 2360315.38% in 2023, then plunged by 116 bps to 5100509.09% in 2024, then surged by 53 bps to 2411550.0% in 2025, then tumbled by 114 bps to 5160800.0% in 2026.
  • According to Business Quant data, Net Margin over the past three periods registered 5160800.0%, 2411550.0%, and 681120.0% for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Margin (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 32.99%
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 30.23%
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 30.33%
4 Revolution Medicines 43.64 Bn 43.64 Bn - -
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 13.90%
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn 30.98%
7 Royalty Pharma 33.72 Bn 35.84 Bn - 12.09%
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 12.74%
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -3.12%
10 Lyell Immunopharma 326.39 Mn 326.39 Mn - -2,573,500.00%

Historic Data

Download Data
DateValue
Jun 30, 2026 -2,573,500.00%
Mar 31, 2026 -5,160,800.00%
Dec 31, 2025 -2,411,550.00%
Sep 30, 2025 -681,120.00%
Jun 30, 2025 -1,443,337.50%
Mar 31, 2025 -1,841,185.71%
Dec 31, 2024 -5,100,509.09%
Sep 30, 2024 -365,905.88%
Jun 30, 2024 -995,992.31%
Mar 31, 2024 -2,496,966.67%
Dec 31, 2023 -2,360,315.38%
Sep 30, 2023 -280,200.00%
Jun 30, 2023 -336,318.52%
Mar 31, 2023 -128,167.69%
Dec 31, 2022 -28.02%
Sep 30, 2022 -6,279,266.67%
Jun 30, 2022 -363.66%
Mar 31, 2022 -31,712.30%
Dec 31, 2021 -6,248.12%
Sep 30, 2021 -2,201.31%