Lyell Immunopharma (LYEL) Net Margin (2020 - 2026)
Lyell Immunopharma (LYEL) posted Net Margin of -1118875.00% for Q2 2026, down 585325.00 percentage points from -533550.00% a year earlier but up 88775.00 percentage points from the prior quarter.
Lyell Immunopharma (LYEL) Net Margin (2020 - 2026) Analysis & Trends
For the trailing twelve months through Jun 30, 2026, Net Margin at Lyell Immunopharma was -920285.19%, down 367956.85 percentage points year-over-year; for FY2025, it came in at -762355.56%, down 200070.31 percentage points from FY2024.
- Annual Net Margin has declined for three consecutive years, with a five-year change of -759673.06 percentage points (FY2020 to FY2025).
- In prior years, Lyell Immunopharma's Net Margin was -562285.25% in FY2024 (-381799.09 pp), -180486.15% in FY2023 (-180269.91 pp), -216.24% in FY2022 (+2133.23 pp) and -2349.47% in FY2021 (+333.02 pp).
- Quarterly Net Margin has run from a low of -2345383.33% in Q4 2025 to a high of -17.35% in Q4 2022 over five years.
- On a year-over-year basis, Net Margin has declined in each of the last five quarters, with an average year-over-year change of -243213.20 percentage points over the last eight quarters.
- The strongest year-over-year quarter for Net Margin in the past five years was Q3 2023, with a gain of 2138388.00 percentage points; the weakest was Q3 2022, with a drop of 2340025.95 percentage points.
- According to Business Quant data, Net Margin for the three prior quarters was -1207650.00% (Q1 2026), -2345383.33% (Q4 2025) and -258973.33% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 21.86% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 21.27% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | -8.04% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | 22.61% |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 18.81% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 23.62% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -134.51% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | -1.65% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 32.99% |
| 10 | Lyell Immunopharma | 227.89 Mn | 227.89 Mn | - | -1,118,875.00% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -1,118,875.00% |
| Mar 31, 2026 | -1,207,650.00% |
| Dec 31, 2025 | -2,345,383.33% |
| Sep 30, 2025 | -258,973.33% |
| Jun 30, 2025 | -533,550.00% |
| Mar 31, 2025 | -745,642.86% |
| Dec 31, 2024 | -1,744,863.64% |
| Sep 30, 2024 | -131,126.47% |
| Jun 30, 2024 | -352,376.92% |
| Mar 31, 2024 | -2,022,233.33% |
| Dec 31, 2023 | -407,153.85% |
| Sep 30, 2023 | -203,412.00% |
| Jun 30, 2023 | -236,629.63% |
| Mar 31, 2023 | -103,013.85% |
| Dec 31, 2022 | -17.35% |
| Sep 30, 2022 | -2,341,800.00% |
| Jun 30, 2022 | -101.63% |
| Mar 31, 2022 | -12,322.60% |
| Dec 31, 2021 | -2,966.19% |
| Sep 30, 2021 | -1,774.05% |
Lyell Immunopharma Net Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=net-margin&ticker=LYEL&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "net-margin", "ticker": "LYEL", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=net-margin&ticker=LYEL&period=max&api_key=YOUR_API_KEY");
const data = await res.json();