Lyell Immunopharma (LYEL) Net Income (2020 - 2026)

Lyell Immunopharma (LYEL) reported Net Income of -$103.2 million for Q1 2026, up 19.91% on a YoY basis from -$86.1 million in Q1 2025, and up 28.67% sequentially from -$144.7 million in Q4 2025.

Lyell Immunopharma (LYEL) Net Income (2020 - 2026) Analysis & Trends

Lyell Immunopharma (LYEL) has 7 years of Net Income data on file, last reported at -$103.2 million in Q1 2026.

  • For the quarter ending Q1 2026, Net Income rose 19.91% year-over-year to -$103.2 million; the trailing twelve-month figure through Mar 2026 stood at -$465.5 million (up 50.67% YoY), and the FY2025 full-year result was -$286.5 million, up 60.08% from the prior year.
  • Net Income advanced to -$103.2 million in Q1 2026, from -$144.7 million in the prior quarter.
  • In the past five years, Net Income ranged from a high of -$70.0 million in Q3 2023 to a low of -$561.1 million in Q4 2024.
  • A 5-year average of -$160.1 million and a median of -$128.9 million in 2025 frame the typical range for Net Income.
  • Across the five-year window, Net Income slumped 216.19% in 2022 and surged 74.21% in 2025, its largest moves.
  • Tracing LYEL's Net Income over 5 years: stood at -$192.5 million in 2022, then slumped by 59.38% to -$306.8 million in 2023, then sank by 82.85% to -$561.1 million in 2024, then surged by 74.21% to -$144.7 million in 2025, then rose by 28.67% to -$103.2 million in 2026.
  • Business Quant data shows LYEL's Net Income at -$103.2 million in Q1 2026, -$144.7 million in Q4 2025, and -$102.2 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Income (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -37.09 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 227.36 Mn
4 NuCana 279.75 Bn 279.75 Bn - -3.31 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 1.03 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 727.20 Mn
7 Belite Bio 62.51 Bn 62.51 Bn - -26.94 Mn
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 362.00 Mn
9 Revolution Medicines 37.78 Bn 37.78 Bn - -453.82 Mn
10 Lyell Immunopharma 298.14 Mn 298.14 Mn - -103.22 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -103.22 Mn
Dec 31, 2025 -144.69 Mn
Sep 30, 2025 -102.17 Mn
Jun 30, 2025 -115.47 Mn
Mar 31, 2025 -128.88 Mn
Dec 31, 2024 -561.06 Mn
Sep 30, 2024 -124.41 Mn
Jun 30, 2024 -129.48 Mn
Mar 31, 2024 -74.91 Mn
Dec 31, 2023 -306.84 Mn
Sep 30, 2023 -70.05 Mn
Jun 30, 2023 -90.81 Mn
Mar 31, 2023 -83.31 Mn
Dec 31, 2022 -192.52 Mn
Sep 30, 2022 -188.38 Mn
Jun 30, 2022 -129.98 Mn
Mar 31, 2022 -175.37 Mn
Dec 31, 2021 -176.32 Mn
Sep 30, 2021 -60.65 Mn
Jun 30, 2021 -173.90 Mn