Lyell Immunopharma (LYEL) Operating Expenses (2020 - 2026)
Lyell Immunopharma recorded quarterly Operating Expenses of $44.3 million in Q1 2026, down 65.32% quarter-over-quarter from $127.6 million in Q4 2025, and down 22.85% year-over-year from $57.4 million in Q1 2025.
Lyell Immunopharma's Operating Expenses history runs 7 years deep, the most recent figure standing at $44.3 million for Q1 2026.
- In Q1 2026, Operating Expenses fell 22.85% year-over-year to $44.3 million; the TTM figure through Mar 2026 stood at $256.3 million (down 28.92% YoY), while the FY2025 annual figure was $269.4 million, down 24.91% from the prior year.
- Operating Expenses came in at $44.3 million for Q1 2026 at Lyell Immunopharma, down from $127.6 million in the prior quarter.
- In the past five years, Operating Expenses ranged from a high of $201.2 million in Q4 2024 to a low of $37.3 million in Q3 2025.
- A 5-year average of $70.1 million and a median of $59.5 million in 2023 frame the typical range for Operating Expenses.
- Across the five-year window, Operating Expenses surged 237.96% in 2024 and slumped 36.54% in 2025, its largest moves.
- Lyell Immunopharma's Operating Expenses stood at $63.2 million in 2022, then retreated by 5.78% to $59.5 million in 2023, then soared by 237.96% to $201.2 million in 2024, then plunged by 36.54% to $127.6 million in 2025, then tumbled by 65.32% to $44.3 million in 2026.
- According to Business Quant data, Operating Expenses over the past three periods registered $44.3 million, $127.6 million, and $37.3 million for Q1 2026, Q4 2025, and Q3 2025 respectively.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 1,216,509.61 Bn | 1,216,509.61 Bn | - | 2.97 Mn |
| 2 | Alterity Therapeutics | 764,224.41 Bn | 764,224.38 Bn | - | 4.33 Mn |
| 3 | Legend Biotech | 2,716.00 Bn | 2,715.71 Bn | 242.10 Mn | -138.30 Mn |
| 4 | Nanobiotix | 2,248.83 Bn | 2,248.77 Bn | - | - |
| 5 | Akari Therapeutics | 1,951.18 Bn | 1,951.17 Bn | - | 15.76 Mn |
| 6 | Vertex Pharmaceuticals | 113.69 Bn | 106.44 Bn | 2.59 Bn | 1.85 Bn |
| 7 | Evaxion A | 64.16 Bn | 64.14 Bn | - | -3.82 Mn |
| 8 | Regeneron Pharmaceuticals | 63.94 Bn | 55.18 Bn | 3.31 Bn | 2.96 Bn |
| 9 | Alnylam Pharmaceuticals | 40.13 Bn | 37.12 Bn | 959.66 Mn | 898.54 Mn |
| 10 | Lyell Immunopharma | 379.11 Mn | 379.11 Mn | - | 44.26 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 44.26 Mn |
| Dec 31, 2025 | 127.65 Mn |
| Sep 30, 2025 | 37.27 Mn |
| Jun 30, 2025 | 47.15 Mn |
| Mar 31, 2025 | 57.37 Mn |
| Dec 31, 2024 | 201.16 Mn |
| Sep 30, 2024 | 50.54 Mn |
| Jun 30, 2024 | 51.54 Mn |
| Mar 31, 2024 | 55.58 Mn |
| Dec 31, 2023 | 59.52 Mn |
| Sep 30, 2023 | 59.06 Mn |
| Jun 30, 2023 | 65.93 Mn |
| Mar 31, 2023 | 62.62 Mn |
| Dec 31, 2022 | 63.17 Mn |
| Sep 30, 2022 | 66.44 Mn |
| Jun 30, 2022 | 73.00 Mn |
| Mar 31, 2022 | 69.13 Mn |
| Dec 31, 2021 | 50.36 Mn |
| Sep 30, 2021 | 51.92 Mn |
| Jun 30, 2021 | 65.34 Mn |
| Mar 31, 2021 | 57.82 Mn |
| Dec 31, 2020 | 41.84 Mn |
| Sep 30, 2020 | 37.91 Mn |
| Jun 30, 2020 | 105.68 Mn |