Lyell Immunopharma (LYEL) Enterprise Value (2020 - 2026)

Lyell Immunopharma (LYEL) reported Enterprise Value of -$254.0 million for Q1 2026, up 15.66% on a YoY basis from -$219.6 million in Q1 2025, and down 2.75% sequentially from -$247.2 million in Q4 2025.

Lyell Immunopharma (LYEL) Enterprise Value (2020 - 2026) Analysis & Trends

Lyell Immunopharma (LYEL) has 7 years of Enterprise Value data on file, last reported at -$254.0 million in Q1 2026.

  • For the quarter ending Q1 2026, Enterprise Value rose 15.66% year-over-year to -$254.0 million; the trailing twelve-month figure through Mar 2026 stood at -$254.0 million (up 15.66% YoY), and the FY2025 full-year result was -$247.2 million, up 33.28% from the prior year.
  • Enterprise Value declined to -$254.0 million in Q1 2026, from -$247.2 million in the prior quarter.
  • In the past five years, Enterprise Value ranged from a high of -$247.2 million in Q4 2025 to a low of -$655.6 million in Q2 2022.
  • A 5-year average of -$477.4 million and a median of -$526.3 million in 2024 frame the typical range for Enterprise Value.
  • Across the five-year window, Enterprise Value slumped 151.22% in 2022 and jumped 43.64% in 2025, its largest moves.
  • Tracing LYEL's Enterprise Value over 5 years: stood at -$640.2 million in 2022, then grew by 14.67% to -$546.2 million in 2023, then soared by 32.17% to -$370.5 million in 2024, then surged by 33.28% to -$247.2 million in 2025, then fell by 2.75% to -$254.0 million in 2026.
  • Business Quant data shows LYEL's Enterprise Value at -$254.0 million in Q1 2026, -$247.2 million in Q4 2025, and -$319.6 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -283.54 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -61.40 Mn
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -2.83 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn -4.79 Bn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn -7.25 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn -8.75 Bn
7 Belite Bio 61.40 Bn 61.40 Bn - -
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn -
9 Revolution Medicines 37.37 Bn 37.37 Bn - -1.91 Bn
10 Lyell Immunopharma 276.08 Mn 276.08 Mn - -254.02 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -254.02 Mn
Dec 31, 2025 -247.22 Mn
Sep 30, 2025 -319.62 Mn
Jun 30, 2025 -276.79 Mn
Mar 31, 2025 -301.18 Mn
Dec 31, 2024 -370.53 Mn
Sep 30, 2024 -440.55 Mn
Jun 30, 2024 -491.12 Mn
Mar 31, 2024 -526.30 Mn
Dec 31, 2023 -546.22 Mn
Sep 30, 2023 -575.43 Mn
Jun 30, 2023 -595.75 Mn
Mar 31, 2023 -612.77 Mn
Dec 31, 2022 -640.15 Mn
Sep 30, 2022 -648.13 Mn
Jun 30, 2022 -655.56 Mn
Mar 31, 2022 -613.91 Mn
Dec 31, 2021 -614.79 Mn
Sep 30, 2021 -618.92 Mn
Jun 30, 2021 -824.52 Mn