Lyell Immunopharma LYEL
NASDAQ LYEL
$14.37 +0.05 (+0.35%)
As of: Sep 4, 2026 · 3:59 PM EDT

Lyell Immunopharma (LYEL) Enterprise Value (2021 - 2026)

Lyell Immunopharma (LYEL) posted Enterprise Value of -$254.0 million for Q1 2026, down 2.75% sequentially from -$247.2 million in Q4 2025, and up 15.66% YoY from -$219.6 million in Q1 2025.

Analysis

Lyell Immunopharma (LYEL) Enterprise Value (2021 - 2026) Analysis & Trends

Lyell Immunopharma has reported Enterprise Value for 7 years, with the latest figure at -$254.0 million in Q1 2026.

  • Quarterly Enterprise Value rose 15.66% year-over-year to -$254.0 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$254.0 million (up 15.66% YoY) and the FY2025 annual result came in at -$247.2 million, up 33.28% from the prior year.
  • Enterprise Value declined to -$254.0 million in Q1 2026 per LYEL's latest filing, from -$247.2 million in the prior quarter.
  • Over five years, Enterprise Value peaked at -$247.2 million in Q4 2025 and troughed at -$655.6 million in Q2 2022.
  • A 5-year average of -$477.4 million and a median of -$526.3 million in 2024 frame the typical range for Enterprise Value.
  • The sharpest annual moves came in 2022 and 2025: Enterprise Value plunged 151.22% in 2022, then soared 43.64% in 2025.
  • Over 5 years, Enterprise Value stood at -$640.2 million in 2022, then gained by 14.67% to -$546.2 million in 2023, then soared by 32.17% to -$370.5 million in 2024, then surged by 33.28% to -$247.2 million in 2025, then slipped by 2.75% to -$254.0 million in 2026.
  • According to Business Quant data, Enterprise Value over the past three periods registered -$254.0 million, -$247.2 million, and -$319.6 million for Q1 2026, Q4 2025, and Q3 2025 respectively.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Vertex Pharmaceuticals 138.47 Bn 130.62 Bn 2.84 Bn
2 Regeneron Pharmaceuticals 85.18 Bn 77.19 Bn 3.93 Bn
3 Argenx Se 63.38 Bn 58.19 Bn 1.37 Bn
4 Moderna 58.09 Bn 52.95 Bn 52.00 Mn
5 Revolution Medicines 44.33 Bn 44.33 Bn -
6 BeOne Medicines 40.02 Bn 34.92 Bn 1.53 Bn
7 Alnylam Pharmaceuticals 35.57 Bn 32.27 Bn 992.69 Mn
8 Royalty Pharma 28.45 Bn 27.61 Bn -
9 Insmed 27.48 Bn 26.32 Bn 358.27 Mn
10 Lyell Immunopharma 335.97 Mn 335.97 Mn -
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 124.63 Mn
Mar 31, 2026 213.94 Mn
Dec 31, 2025 278.90 Mn
Sep 30, 2025 -6.29 Mn
Jun 30, 2025 -145.68 Mn
Mar 31, 2025 -142.31 Mn
Dec 31, 2024 -181.81 Mn
Sep 30, 2024 -86.49 Mn
Jun 30, 2024 -119.99 Mn
Mar 31, 2024 42.19 Mn
Dec 31, 2023 -53.54 Mn
Sep 30, 2023 -205.18 Mn
Jun 30, 2023 202.52 Mn
Mar 31, 2023 -23.69 Mn
Dec 31, 2022 225.85 Mn
Sep 30, 2022 1.18 Bn
Jun 30, 2022 955.59 Mn
Mar 31, 2022 625.47 Mn
Dec 31, 2021 437.21 Mn
Sep 30, 2021 2.93 Bn