Lyell Immunopharma (LYEL) Enterprise Value (2020 - 2026)
Lyell Immunopharma (LYEL) reported Enterprise Value of -$254.0 million for Q1 2026, up 15.66% on a YoY basis from -$219.6 million in Q1 2025, and down 2.75% sequentially from -$247.2 million in Q4 2025.
Lyell Immunopharma (LYEL) Enterprise Value (2020 - 2026) Analysis & Trends
Lyell Immunopharma (LYEL) has 7 years of Enterprise Value data on file, last reported at -$254.0 million in Q1 2026.
- For the quarter ending Q1 2026, Enterprise Value rose 15.66% year-over-year to -$254.0 million; the trailing twelve-month figure through Mar 2026 stood at -$254.0 million (up 15.66% YoY), and the FY2025 full-year result was -$247.2 million, up 33.28% from the prior year.
- Enterprise Value declined to -$254.0 million in Q1 2026, from -$247.2 million in the prior quarter.
- In the past five years, Enterprise Value ranged from a high of -$247.2 million in Q4 2025 to a low of -$655.6 million in Q2 2022.
- A 5-year average of -$477.4 million and a median of -$526.3 million in 2024 frame the typical range for Enterprise Value.
- Across the five-year window, Enterprise Value slumped 151.22% in 2022 and jumped 43.64% in 2025, its largest moves.
- Tracing LYEL's Enterprise Value over 5 years: stood at -$640.2 million in 2022, then grew by 14.67% to -$546.2 million in 2023, then soared by 32.17% to -$370.5 million in 2024, then surged by 33.28% to -$247.2 million in 2025, then fell by 2.75% to -$254.0 million in 2026.
- Business Quant data shows LYEL's Enterprise Value at -$254.0 million in Q1 2026, -$247.2 million in Q4 2025, and -$319.6 million in Q3 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Enterprise Value (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 67,072.09 Bn | 67,072.09 Bn | - | -283.54 Mn |
| 2 | Nanobiotix | 1,894.61 Bn | 1,894.55 Bn | - | -61.40 Mn |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | -2.83 Mn |
| 4 | BeOne Medicines | 471.64 Bn | 466.85 Bn | 1.35 Bn | -4.79 Bn |
| 5 | Vertex Pharmaceuticals | 121.72 Bn | 114.47 Bn | 2.59 Bn | -7.25 Bn |
| 6 | Regeneron Pharmaceuticals | 68.28 Bn | 59.52 Bn | 3.31 Bn | -8.75 Bn |
| 7 | Belite Bio | 61.40 Bn | 61.40 Bn | - | - |
| 8 | Argenx Se | 56.94 Bn | 56.94 Bn | 1.18 Bn | - |
| 9 | Revolution Medicines | 37.37 Bn | 37.37 Bn | - | -1.91 Bn |
| 10 | Lyell Immunopharma | 276.08 Mn | 276.08 Mn | - | -254.02 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -254.02 Mn |
| Dec 31, 2025 | -247.22 Mn |
| Sep 30, 2025 | -319.62 Mn |
| Jun 30, 2025 | -276.79 Mn |
| Mar 31, 2025 | -301.18 Mn |
| Dec 31, 2024 | -370.53 Mn |
| Sep 30, 2024 | -440.55 Mn |
| Jun 30, 2024 | -491.12 Mn |
| Mar 31, 2024 | -526.30 Mn |
| Dec 31, 2023 | -546.22 Mn |
| Sep 30, 2023 | -575.43 Mn |
| Jun 30, 2023 | -595.75 Mn |
| Mar 31, 2023 | -612.77 Mn |
| Dec 31, 2022 | -640.15 Mn |
| Sep 30, 2022 | -648.13 Mn |
| Jun 30, 2022 | -655.56 Mn |
| Mar 31, 2022 | -613.91 Mn |
| Dec 31, 2021 | -614.79 Mn |
| Sep 30, 2021 | -618.92 Mn |
| Jun 30, 2021 | -824.52 Mn |