Lyell Immunopharma (LYEL) Enterprise Value (2021 - 2026)
Lyell Immunopharma (LYEL) posted Enterprise Value of -$254.0 million for Q1 2026, down 2.75% sequentially from -$247.2 million in Q4 2025, and up 15.66% YoY from -$219.6 million in Q1 2025.
Analysis
Lyell Immunopharma (LYEL) Enterprise Value (2021 - 2026) Analysis & Trends
Lyell Immunopharma has reported Enterprise Value for 7 years, with the latest figure at -$254.0 million in Q1 2026.
- Quarterly Enterprise Value rose 15.66% year-over-year to -$254.0 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$254.0 million (up 15.66% YoY) and the FY2025 annual result came in at -$247.2 million, up 33.28% from the prior year.
- Enterprise Value declined to -$254.0 million in Q1 2026 per LYEL's latest filing, from -$247.2 million in the prior quarter.
- Over five years, Enterprise Value peaked at -$247.2 million in Q4 2025 and troughed at -$655.6 million in Q2 2022.
- A 5-year average of -$477.4 million and a median of -$526.3 million in 2024 frame the typical range for Enterprise Value.
- The sharpest annual moves came in 2022 and 2025: Enterprise Value plunged 151.22% in 2022, then soared 43.64% in 2025.
- Over 5 years, Enterprise Value stood at -$640.2 million in 2022, then gained by 14.67% to -$546.2 million in 2023, then soared by 32.17% to -$370.5 million in 2024, then surged by 33.28% to -$247.2 million in 2025, then slipped by 2.75% to -$254.0 million in 2026.
- According to Business Quant data, Enterprise Value over the past three periods registered -$254.0 million, -$247.2 million, and -$319.6 million for Q1 2026, Q4 2025, and Q3 2025 respectively.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) |
|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 138.47 Bn | 130.62 Bn | 2.84 Bn |
| 2 | Regeneron Pharmaceuticals | 85.18 Bn | 77.19 Bn | 3.93 Bn |
| 3 | Argenx Se | 63.38 Bn | 58.19 Bn | 1.37 Bn |
| 4 | Moderna | 58.09 Bn | 52.95 Bn | 52.00 Mn |
| 5 | Revolution Medicines | 44.33 Bn | 44.33 Bn | - |
| 6 | BeOne Medicines | 40.02 Bn | 34.92 Bn | 1.53 Bn |
| 7 | Alnylam Pharmaceuticals | 35.57 Bn | 32.27 Bn | 992.69 Mn |
| 8 | Royalty Pharma | 28.45 Bn | 27.61 Bn | - |
| 9 | Insmed | 27.48 Bn | 26.32 Bn | 358.27 Mn |
| 10 | Lyell Immunopharma | 335.97 Mn | 335.97 Mn | - |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 124.63 Mn |
| Mar 31, 2026 | 213.94 Mn |
| Dec 31, 2025 | 278.90 Mn |
| Sep 30, 2025 | -6.29 Mn |
| Jun 30, 2025 | -145.68 Mn |
| Mar 31, 2025 | -142.31 Mn |
| Dec 31, 2024 | -181.81 Mn |
| Sep 30, 2024 | -86.49 Mn |
| Jun 30, 2024 | -119.99 Mn |
| Mar 31, 2024 | 42.19 Mn |
| Dec 31, 2023 | -53.54 Mn |
| Sep 30, 2023 | -205.18 Mn |
| Jun 30, 2023 | 202.52 Mn |
| Mar 31, 2023 | -23.69 Mn |
| Dec 31, 2022 | 225.85 Mn |
| Sep 30, 2022 | 1.18 Bn |
| Jun 30, 2022 | 955.59 Mn |
| Mar 31, 2022 | 625.47 Mn |
| Dec 31, 2021 | 437.21 Mn |
| Sep 30, 2021 | 2.93 Bn |