Lyell Immunopharma (LYEL) Free Cash Flow (2020 - 2026)

Lyell Immunopharma (LYEL) reported Free Cash Flow of -$38.6 million for Q1 2026, up 29.68% on a YoY basis from -$29.8 million in Q1 2025, and down 16.86% sequentially from -$33.0 million in Q4 2025.

Lyell Immunopharma (LYEL) Free Cash Flow (2020 - 2026) Analysis & Trends

Lyell Immunopharma (LYEL) has 7 years of Free Cash Flow data on file, last reported at -$38.6 million in Q1 2026.

  • For the quarter ending Q1 2026, Free Cash Flow rose 29.68% year-over-year to -$38.6 million; the trailing twelve-month figure through Mar 2026 stood at -$134.5 million (up 23.31% YoY), and the FY2025 full-year result was -$150.8 million, up 7.22% from the prior year.
  • Free Cash Flow declined to -$38.6 million in Q1 2026, from -$33.0 million in the prior quarter.
  • In the past five years, Free Cash Flow ranged from a high of -$21.9 million in Q4 2022 to a low of -$54.9 million in Q1 2025.
  • A 5-year average of -$40.5 million and a median of -$40.1 million in 2023 frame the typical range for Free Cash Flow.
  • Peak annual rise in Free Cash Flow reached 76.53% in 2022, while the deepest fall reached 118.71% in 2022.
  • Tracing LYEL's Free Cash Flow over 5 years: stood at -$21.9 million in 2022, then slumped by 97.82% to -$43.3 million in 2023, then decreased by 8.42% to -$47.0 million in 2024, then advanced by 29.67% to -$33.0 million in 2025, then slipped by 16.86% to -$38.6 million in 2026.
  • Business Quant data shows LYEL's Free Cash Flow at -$38.6 million in Q1 2026, -$33.0 million in Q4 2025, and -$28.2 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Free Cash Flow (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -19.58 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 158.09 Mn
4 NuCana 279.75 Bn 279.75 Bn - -1.53 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 1.29 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 848.30 Mn
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -
9 Revolution Medicines 37.78 Bn 37.78 Bn - -354.95 Mn
10 Lyell Immunopharma 298.14 Mn 298.14 Mn - -38.60 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -38.60 Mn
Mar 31, 2026 -38.60 Mn
Dec 31, 2025 -33.03 Mn
Dec 31, 2025 -33.03 Mn
Sep 30, 2025 -28.16 Mn
Sep 30, 2025 -28.16 Mn
Jun 30, 2025 -34.72 Mn
Jun 30, 2025 -34.72 Mn
Mar 31, 2025 -54.89 Mn
Mar 31, 2025 -54.89 Mn
Dec 31, 2024 -46.97 Mn
Dec 31, 2024 -46.97 Mn
Sep 30, 2024 -35.41 Mn
Sep 30, 2024 -35.41 Mn
Jun 30, 2024 -38.11 Mn
Jun 30, 2024 -38.11 Mn
Mar 31, 2024 -42.05 Mn
Mar 31, 2024 -42.05 Mn
Dec 31, 2023 -43.32 Mn
Dec 31, 2023 -43.32 Mn