Lyell Immunopharma LYEL
NASDAQ LYEL
$14.37 +0.05 (+0.35%)
As of: Sep 4, 2026 · 3:59 PM EDT

Lyell Immunopharma (LYEL) Free Cash Flow (2020 - 2026)

Lyell Immunopharma (LYEL) posted Free Cash Flow of -$38.6 million for Q1 2026, down 16.86% sequentially from -$33.0 million in Q4 2025, and up 29.68% YoY from -$29.8 million in Q1 2025.

Analysis

Lyell Immunopharma (LYEL) Free Cash Flow (2020 - 2026) Analysis & Trends

Lyell Immunopharma has reported Free Cash Flow for 7 years, with the latest figure at -$38.6 million in Q1 2026.

  • Quarterly Free Cash Flow rose 29.68% year-over-year to -$38.6 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$134.5 million (up 23.31% YoY) and the FY2025 annual result came in at -$150.8 million, up 7.22% from the prior year.
  • Free Cash Flow declined to -$38.6 million in Q1 2026 per LYEL's latest filing, from -$33.0 million in the prior quarter.
  • Over five years, Free Cash Flow peaked at -$21.9 million in Q4 2022 and troughed at -$54.9 million in Q1 2025.
  • A 5-year average of -$40.5 million and a median of -$40.1 million in 2023 frame the typical range for Free Cash Flow.
  • The widest YoY moves for Free Cash Flow: up 76.53% in 2022, down 118.71% in 2022.
  • Over 5 years, Free Cash Flow stood at -$21.9 million in 2022, then sank by 97.82% to -$43.3 million in 2023, then declined by 8.42% to -$47.0 million in 2024, then increased by 29.67% to -$33.0 million in 2025, then fell by 16.86% to -$38.6 million in 2026.
  • According to Business Quant data, Free Cash Flow over the past three periods registered -$38.6 million, -$33.0 million, and -$28.2 million for Q1 2026, Q4 2025, and Q3 2025 respectively.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Free Cash Flow (Qtr)
1 Vertex Pharmaceuticals 138.47 Bn 130.62 Bn 2.84 Bn 1.01 Bn
2 Regeneron Pharmaceuticals 85.18 Bn 77.19 Bn 3.93 Bn 572.80 Mn
3 Argenx Se 63.38 Bn 58.19 Bn 1.37 Bn -
4 Moderna 58.09 Bn 52.95 Bn 52.00 Mn -563.00 Mn
5 Revolution Medicines 44.33 Bn 44.33 Bn - -389.61 Mn
6 BeOne Medicines 40.02 Bn 34.92 Bn 1.53 Bn 437.80 Mn
7 Alnylam Pharmaceuticals 35.57 Bn 32.27 Bn 992.69 Mn 292.04 Mn
8 Royalty Pharma 28.45 Bn 27.61 Bn - 477.44 Mn
9 Insmed 27.48 Bn 26.32 Bn 358.27 Mn -95.09 Mn
10 Lyell Immunopharma 335.97 Mn 335.97 Mn - -34.08 Mn
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 -34.08 Mn
Mar 31, 2026 -38.70 Mn
Dec 31, 2025 -32.56 Mn
Sep 30, 2025 -28.64 Mn
Jun 30, 2025 -34.63 Mn
Mar 31, 2025 -54.98 Mn
Dec 31, 2024 -47.29 Mn
Sep 30, 2024 -35.10 Mn
Jun 30, 2024 -38.24 Mn
Mar 31, 2024 -42.24 Mn
Dec 31, 2023 -40.66 Mn
Sep 30, 2023 -37.88 Mn
Jun 30, 2023 -40.09 Mn
Mar 31, 2023 -47.75 Mn
Dec 31, 2022 -44.85 Mn
Sep 30, 2022 -39.89 Mn
Jun 30, 2022 -51.50 Mn
Mar 31, 2022 -57.59 Mn
Dec 31, 2021 -43.48 Mn
Sep 30, 2021 -37.09 Mn