Lyell Immunopharma (LYEL) EBIT (2020 - 2026)

Lyell Immunopharma (LYEL) reported EBIT of -$44.3 million for Q1 2026, up 22.85% on a YoY basis from -$36.0 million in Q1 2025, and up 65.32% sequentially from -$127.6 million in Q4 2025.

Lyell Immunopharma (LYEL) EBIT (2020 - 2026) Analysis & Trends

Lyell Immunopharma (LYEL) has 7 years of EBIT data on file, last reported at -$44.3 million in Q1 2026.

  • For the quarter ending Q1 2026, EBIT rose 22.85% year-over-year to -$44.3 million; the trailing twelve-month figure through Mar 2026 stood at -$256.3 million (up 28.91% YoY), and the FY2025 full-year result was -$269.4 million, up 24.91% from the prior year.
  • EBIT advanced to -$44.3 million in Q1 2026, from -$127.6 million in the prior quarter.
  • In the past five years, EBIT ranged from a high of -$14.8 million in Q4 2022 to a low of -$201.1 million in Q4 2024.
  • A 5-year average of -$65.1 million and a median of -$57.4 million in 2025 frame the typical range for EBIT.
  • Across the five-year window, EBIT jumped 68.9% in 2022 and slumped 302.52% in 2023, its largest moves.
  • Tracing LYEL's EBIT over 5 years: stood at -$14.8 million in 2022, then tumbled by 302.52% to -$59.5 million in 2023, then sank by 238.02% to -$201.1 million in 2024, then soared by 36.54% to -$127.6 million in 2025, then surged by 65.32% to -$44.3 million in 2026.
  • Business Quant data shows LYEL's EBIT at -$44.3 million in Q1 2026, -$127.6 million in Q4 2025, and -$37.3 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBIT (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -27.75 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -15.76 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 249.90 Mn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.14 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 642.90 Mn
7 Belite Bio 61.40 Bn 61.40 Bn - -32.68 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn 394.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - -445.22 Mn
10 Lyell Immunopharma 276.08 Mn 276.08 Mn - -44.26 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -44.26 Mn
Dec 31, 2025 -127.64 Mn
Sep 30, 2025 -37.25 Mn
Jun 30, 2025 -47.14 Mn
Mar 31, 2025 -57.37 Mn
Dec 31, 2024 -201.15 Mn
Sep 30, 2024 -50.51 Mn
Jun 30, 2024 -51.53 Mn
Mar 31, 2024 -55.58 Mn
Dec 31, 2023 -59.51 Mn
Sep 30, 2023 -59.04 Mn
Jun 30, 2023 -65.91 Mn
Mar 31, 2023 -62.56 Mn
Dec 31, 2022 -14.78 Mn
Sep 30, 2022 -66.44 Mn
Jun 30, 2022 -37.26 Mn
Mar 31, 2022 -68.58 Mn
Dec 31, 2021 -47.54 Mn
Sep 30, 2021 -49.16 Mn
Jun 30, 2021 -62.71 Mn