Lyell Immunopharma (LYEL) Profit After Tax (2020 - 2026)

Lyell Immunopharma (LYEL) reported Profit After Tax of -$24.4 million for Q1 2026, up 53.24% on a YoY basis from -$15.9 million in Q1 2025, and up 82.66% sequentially from -$140.8 million in Q4 2025.

Lyell Immunopharma (LYEL) Profit After Tax (2020 - 2026) Analysis & Trends

Lyell Immunopharma (LYEL) has 7 years of Profit After Tax data on file, last reported at -$24.4 million in Q1 2026.

  • For the quarter ending Q1 2026, Profit After Tax rose 53.24% year-over-year to -$24.4 million; the trailing twelve-month figure through Mar 2026 stood at -$246.6 million (up 26.14% YoY), and the FY2025 full-year result was -$274.5 million, up 19.88% from the prior year.
  • Profit After Tax advanced to -$24.4 million in Q1 2026, from -$140.8 million in the prior quarter.
  • In the past five years, Profit After Tax ranged from a high of -$6.0 million in Q4 2022 to a low of -$192.4 million in Q4 2024.
  • A 5-year average of -$62.2 million and a median of -$52.2 million in 2025 frame the typical range for Profit After Tax.
  • Across the five-year window, Profit After Tax surged 92.99% in 2022 and plunged 782.17% in 2023, its largest moves.
  • Tracing LYEL's Profit After Tax over 5 years: stood at -$6.0 million in 2022, then tumbled by 782.17% to -$52.9 million in 2023, then plunged by 263.51% to -$192.4 million in 2024, then rose by 26.84% to -$140.8 million in 2025, then soared by 82.66% to -$24.4 million in 2026.
  • Business Quant data shows LYEL's Profit After Tax at -$24.4 million in Q1 2026, -$140.8 million in Q4 2025, and -$38.7 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) PAT (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -36.84 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 227.36 Mn
4 NuCana 279.75 Bn 279.75 Bn - -
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 1.03 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn -65.60 Mn
7 Belite Bio 62.51 Bn 62.51 Bn - -26.94 Mn
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 362.00 Mn
9 Revolution Medicines 37.78 Bn 37.78 Bn - -453.82 Mn
10 Lyell Immunopharma 298.14 Mn 298.14 Mn - -24.40 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -24.40 Mn
Dec 31, 2025 -140.77 Mn
Sep 30, 2025 -38.70 Mn
Jun 30, 2025 -42.68 Mn
Mar 31, 2025 -52.20 Mn
Dec 31, 2024 -192.40 Mn
Sep 30, 2024 -43.43 Mn
Jun 30, 2024 -45.81 Mn
Mar 31, 2024 -60.67 Mn
Dec 31, 2023 -52.93 Mn
Sep 30, 2023 -49.66 Mn
Jun 30, 2023 -63.89 Mn
Mar 31, 2023 -66.96 Mn
Dec 31, 2022 -6.00 Mn
Sep 30, 2022 -71.90 Mn
Jun 30, 2022 -36.32 Mn
Mar 31, 2022 -68.14 Mn
Dec 31, 2021 -85.59 Mn
Sep 30, 2021 -48.88 Mn
Jun 30, 2021 -62.60 Mn