Lyell Immunopharma (LYEL) Return on Sales (2020 - 2025)

Lyell Immunopharma (LYEL) has disclosed Return on Sales for 6 consecutive years, with 20828.0% as the latest value for Q4 2025.

  • Quarterly Return on Sales fell 298918.0% to 20828.0% in Q4 2025 from the year-ago period, while the trailing twelve-month figure was 7120.11% through Dec 2025, down 163344.0% year-over-year, with the annual reading at 7120.11% for FY2025, 163344.0% down from the prior year.
  • Return on Sales hit 20828.0% in Q4 2025 for Lyell Immunopharma, down from 2265.8% in the prior quarter.
  • In the past five years, Return on Sales ranged from a high of 0.23% in Q4 2022 to a low of 21395.33% in Q3 2022.
  • Historically, Return on Sales has averaged 5298.25% across 5 years, with a median of 2171.6% in 2023.
  • Biggest five-year swings in Return on Sales: crashed -2137759bps in 2022 and later soared 1929809bps in 2023.
  • Year by year, Return on Sales stood at 16.73% in 2021, then soared by 99bps to 0.23% in 2022, then plummeted by -1721920bps to 4032.62% in 2023, then plummeted by -342bps to 17838.82% in 2024, then dropped by -17bps to 20828.0% in 2025.
  • Business Quant data shows Return on Sales for LYEL at 20828.0% in Q4 2025, 2265.8% in Q3 2025, and 5483.0% in Q2 2025.