Ionis Pharmaceuticals Ratios (2009-2026) | IONS

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Ratios	Jun2021	Sep2021	Dec2021	Mar2022	Jun2022	Sep2022	Dec2022	Mar2023	Jun2023	Sep2023	Dec2023	Mar2024	Jun2024	Sep2024	Dec2024	Mar2025	Jun2025	Sep2025	Dec2025	Mar2026
Profitability
Gross Margin (Quarter)	97.65%	97.69%	96.29%	97.06%	96.45%	99.05%	97.57%	98.97%	98.65%	98.48%	99.06%	98.20%	98.15%	99.20%	98.31%	98.89%	-107.55%	98.51%	96.09%	98.79%
EBT Margin (Quarter)	-64.05%	-62.94%	374.86%	-45.15%	-76.89%	-29.24%	-29.19%	-86.53%	-41.11%	-97.64%	-0.85%	-119.44%	-29.39%	-107.69%	-47.53%	-111.56%	6,176.55%	-81.93%	75.38%	-37.51%
EBIT Margin (Quarter)	-58.03%	-64.50%	367.67%	-40.52%	-63.92%	-37.03%	-136.95%	-87.45%	-47.87%	-99.35%	-1.89%	-125.12%	-29.34%	-111.09%	-48.91%	-111.59%	6,990.80%	-102.21%	-105.47%	-47.72%
EBITDA Margin (Quarter)	-58.03%	-64.50%	367.67%	-40.52%	-63.92%	-37.03%	-136.95%	-87.45%	-47.87%	-99.35%	-1.89%	-125.12%	-29.34%	-111.09%	-48.91%	-111.59%	6,990.80%	-102.21%	-105.47%	-47.72%
Operating Margin (Quarter)	-58.03%	-64.50%	367.67%	-40.52%	-63.92%	-37.03%	-136.95%	-87.45%	-47.87%	-99.35%	-1.89%	-125.12%	-29.34%	-111.09%	-48.91%	-111.59%	6,990.80%	-102.21%	-105.47%	-47.72%
Net Margin (Quarter)	-64.31%	-61.96%	374.36%	-45.92%	-78.58%	-29.41%	-34.52%	-95.26%	-45.25%	-102.22%	-2.85%	-119.50%	-29.42%	-104.98%	-46.35%	-111.64%	6,177.55%	-82.06%	60.76%	-37.60%
FCF Margin (Quarter)	-53.29%	-44.25%	335.31%	-24.21%	-16.02%	-18.76%	-134.53%	-110.68%	-58.05%	-77.09%	10.38%	-129.23%	-55.99%	-92.70%	-62.51%	-124.12%	6,951.65%	-87.23%	-53.13%	-331.01%
Efficiency
Inventory Average (Quarter)	23.15M	23.51M	23.87M	24.42M	21.92M	20.23M	21.34M	22.12M	23.87M	25.59M	16.54M	18.85M	29.49M	28.59M	20.48M	12.01M	9.99M	9.48M	10.26M	7.80M
Assets Average (Quarter)	2,372.81M	2,455.98M	2,513.29M	2,565.39M	2,487.61M	2,439.05M	2,477.92M	2,709.55M	2,928.18M	2,952.55M	2,962.02M	2,877.00M	2,727.53M	2,886.11M	3,042.39M	2,908.31M	2,899.04M	3,009.11M	3,278.46M	3,486.90M
Equity Average (Quarter)	631.62M	556.61M	651.14M	740.66M	667.15M	609.54M	583.62M	529.73M	457.44M	371.88M	351.07M	341.60M	280.11M	463.08M	625.41M	532.04M	553.73M	624.85M	553.53M	490.25M
Invested Capital (Quarter)	590.65M	533.64M	775.26M	713.78M	629.46M	599.33M	572.89M	486.57M	428.30M	315.46M	431.02M	340.89M	308.12M	706.93M	588.35M	475.73M	1,261.84M	1,248.88M	921.04M	923.91M
Asset Utilization Ratio (Quarter)	0.18	0.17	0.17	0.18	0.19	0.20	0.24	0.21	0.22	0.21	0.27	0.27	0.30	0.28	0.23	0.25	0.17	0.17	0.15	0.25
Leverage & Solvency
Interest Coverage Ratio (Quarter)	-30.96	-36.69	98.57	-27.10	-40.15	-27.65	-120.17	-70.99	-39.37	-34.09	-1.34	-36.02	-14.72	-35.73	-26.44	-35.75	33.99	-38.03	-44.42	-22.76
Debt to Equity (Quarter)	0.12	0.05	0.08	0.04	0.05	0.11	0.03	0.02			0.22	0.15	0.17	0.07	0.09		1.00	1.02	0.94	0.88
Debt Ratio (Quarter)	0.03	0.01	0.02	0.01	0.01	0.03	0.01	0.00			0.03	0.02	0.02	0.01	0.02		0.21	0.21	0.13	0.13
Equity Ratio (Quarter)	0.23	0.22	0.30	0.28	0.25	0.25	0.23	0.17	0.14	0.11	0.13	0.11	0.10	0.22	0.20	0.17	0.21	0.20	0.14	0.14
Times Interest Earned (Quarter)	-30.96	-36.69	98.57	-27.10	-40.15	-27.65	-120.17	-70.99	-39.37	-34.09	-1.34	-36.02	-14.72	-35.73	-26.44	-35.75	33.99	-38.03	-44.42	-22.76
Valuation
Enterprise Value (Quarter)	-2059.27M	-1987.10M	-2114.97M	-2052.39M	-2021.83M	-1981.66M	-1986.87M	-2346.78M	-2385.39M	-2235.58M	-2331.20M	-2206.22M	-2078.69M	-2483.28M	-2297.66M	-2145.15M	-2289.98M	-2240.17M	-2677.44M	-1919.11M
Return Ratios
Return on Sales (Quarter)	-0.64%	-0.62%	3.74%	-0.46%	-0.79%	-0.29%	-0.35%	-0.95%	-0.45%	-1.02%	-0.03%	-1.20%	-0.29%	-1.05%	-0.46%	-1.12%	61.78%	-0.82%	0.75%	-0.38%
Return on Capital Employed (Quarter)	-0.11%	-0.13%	-0.01%	0.00%	0.00%	0.01%	-0.19%	-0.19%	-0.18%	-0.22%	-0.14%	-0.15%	-0.15%	-0.14%	-0.17%	-0.18%	-0.13%	-0.13%	-0.15%	-0.13%
Return on Invested Capital (Quarter)	-0.34%	-0.48%	-0.05%	0.01%	-0.01%	0.02%	-0.73%	-0.94%	-1.13%	-1.63%	-1.04%	-1.07%	-1.17%	-0.74%	-0.72%	-0.88%	-0.30%	-0.22%	0.05%	-0.37%
Return on Assets (Quarter)	-0.09%	-0.11%	-0.01%	0.00%	-0.01%	0.00%	-0.11%	-0.12%	-0.11%	-0.14%	-0.12%	-0.13%	-0.13%	-0.12%	-0.15%	-0.16%	-0.09%	-0.09%	0.00%	0.02%
Return on Equity (Quarter)	-0.35%	-0.48%	-0.04%	-0.01%	-0.04%	0.01%	-0.46%	-0.62%	-0.68%	-1.10%	-1.04%	-1.13%	-1.31%	-0.77%	-0.73%	-0.86%	-0.49%	-0.41%	0.00%	0.11%

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Ionis Pharmaceuticals Ratios (2009-2026) | IONS

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