Ionis Pharmaceuticals IONS
NASDAQ IONS
$58.09 -0.04 (-0.07%)
As of: Sep 4, 2026 · 3:59 PM EDT

Ionis Pharmaceuticals (IONS) FCF Margin (2009 - 2026)

Ionis Pharmaceuticals (IONS) posted quarterly FCF Margin of 205.06% for Q2 2026, up 17430.0% year-over-year from N/an in Q2 2025, and up 112.59% quarter-over-quarter from 1629.16% in Q1 2026.

Analysis

Ionis Pharmaceuticals (IONS) FCF Margin (2009 - 2026) Analysis & Trends

Ionis Pharmaceuticals' FCF Margin history runs 18 years deep, the most recent figure standing at 205.06% for Q2 2026.

  • In Q2 2026, FCF Margin rose 17430.0% year-over-year to 205.06%; the TTM figure through Jun 2026 stood at 82.72% (down 5200.0% YoY), while the FY2025 annual figure was 33.91%, up 4355.0% from the prior year.
  • FCF Margin for Q2 2026 stood at 205.06%, up from 1629.16% in the prior quarter.
  • The five-year high for FCF Margin was 205.06% in Q2 2026, with the low at 1629.16% in Q1 2026.
  • The 5-year median for FCF Margin is 69.8% (2024), against an average of 136.24%.
  • Peak annual rise in FCF Margin reached 17430 bps in 2026, while the deepest fall reached 150505 bps in 2026.
  • Ionis Pharmaceuticals' FCF Margin stood at 134.53% in 2022, then soared by 108 bps to 10.38% in 2023, then plunged by 702 bps to 62.51% in 2024, then declined by 25 bps to 78.2% in 2025, then surged by 362 bps to 205.06% in 2026.
  • Business Quant data shows IONS's FCF Margin at 205.06% in Q2 2026, 1629.16% in Q1 2026, and 78.2% in Q4 2025.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) FCF Margin (Qtr)
1 Vertex Pharmaceuticals 138.47 Bn 130.62 Bn 2.84 Bn 30.39%
2 Regeneron Pharmaceuticals 85.18 Bn 77.19 Bn 3.93 Bn 13.35%
3 Argenx Se 63.38 Bn 58.19 Bn 1.37 Bn -
4 Moderna 58.09 Bn 52.95 Bn 52.00 Mn -388.28%
5 Revolution Medicines 44.33 Bn 44.33 Bn - -
6 BeOne Medicines 40.02 Bn 34.92 Bn 1.53 Bn 25.68%
7 Alnylam Pharmaceuticals 35.57 Bn 32.27 Bn 992.69 Mn 22.62%
8 Royalty Pharma 28.45 Bn 27.61 Bn - 70.82%
9 Insmed 27.48 Bn 26.32 Bn 358.27 Mn -22.35%
10 Ionis Pharmaceuticals 9.60 Bn 7.55 Bn 265.21 Mn 205.06%
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 205.06%
Mar 31, 2026 -331.01%
Dec 31, 2025 -78.20%
Sep 30, 2025 -87.23%
Jun 30, 2025 30.76%
Mar 31, 2025 -124.12%
Dec 31, 2024 -62.51%
Sep 30, 2024 -92.70%
Jun 30, 2024 -55.99%
Mar 31, 2024 -129.23%
Dec 31, 2023 10.38%
Sep 30, 2023 -77.09%
Jun 30, 2023 -58.05%
Mar 31, 2023 -110.68%
Dec 31, 2022 -134.53%
Sep 30, 2022 -18.76%
Jun 30, 2022 -16.02%
Mar 31, 2022 -24.21%
Dec 31, 2021 45.72%
Sep 30, 2021 -44.25%