Ionis Pharmaceuticals (IONS) FCF Margin (2009 - 2026)
Ionis Pharmaceuticals (IONS) recorded quarterly FCF Margin of 331.01% in Q1 2026, down 323.29% quarter-over-quarter from 78.2% in Q4 2025, and down 20689.0% on a YoY basis from N/an in Q1 2025.
Ionis Pharmaceuticals (IONS) FCF Margin (2009 - 2026) Analysis & Trends
Ionis Pharmaceuticals' FCF Margin history runs 18 years deep, the most recent figure standing at 331.01% for Q1 2026.
- In Q1 2026, FCF Margin fell 20689.0% year-over-year to 331.01%; the TTM figure through Mar 2026 stood at 159.71% (down 8231.0% YoY), while the FY2025 annual figure was 33.91%, up 4355.0% from the prior year.
- FCF Margin was 331.01% for Q1 2026 at Ionis Pharmaceuticals, down from 78.2% in the prior quarter.
- In the past five years, FCF Margin ranged from a high of 6951.65% in Q2 2025 to a low of 331.01% in Q1 2026.
- Historically, FCF Margin has averaged 327.59% across 5 years, with a median of 77.09% in 2023.
- The sharpest annual moves came in 2025 and 2026: FCF Margin soared 700764 bps in 2025, then plunged 20689 bps in 2026.
- A 5-year view of FCF Margin shows it stood at 134.53% in 2022, then surged by 113 bps to 17.66% in 2023, then sank by 454 bps to 62.51% in 2024, then fell by 25 bps to 78.2% in 2025, then slumped by 323 bps to 331.01% in 2026.
- The last three FCF Margin figures came in at 331.01% (Q1 2026), 78.2% (Q4 2025), and 87.23% (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | FCF Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | - |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -3.98% |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | - |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 43.35% |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | - |
| 10 | Ionis Pharmaceuticals | 12.23 Bn | 10.31 Bn | 243.11 Mn | -331.01% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -331.01% |
| Dec 31, 2025 | -78.20% |
| Sep 30, 2025 | -87.23% |
| Jun 30, 2025 | 6,951.65% |
| Mar 31, 2025 | -124.12% |
| Dec 31, 2024 | -62.51% |
| Sep 30, 2024 | -92.70% |
| Jun 30, 2024 | -55.99% |
| Mar 31, 2024 | -129.23% |
| Dec 31, 2023 | 17.66% |
| Sep 30, 2023 | -77.09% |
| Jun 30, 2023 | -58.05% |
| Mar 31, 2023 | -110.68% |
| Dec 31, 2022 | -134.53% |
| Sep 30, 2022 | -18.76% |
| Jun 30, 2022 | -16.02% |
| Mar 31, 2022 | -24.21% |
| Dec 31, 2021 | 45.72% |
| Sep 30, 2021 | -44.25% |
| Jun 30, 2021 | -53.29% |