Ionis Pharmaceuticals (IONS) FCF Margin (2009 - 2026)
Ionis Pharmaceuticals (IONS) posted quarterly FCF Margin of 205.06% for Q2 2026, up 17430.0% year-over-year from N/an in Q2 2025, and up 112.59% quarter-over-quarter from 1629.16% in Q1 2026.
Ionis Pharmaceuticals (IONS) FCF Margin (2009 - 2026) Analysis & Trends
Ionis Pharmaceuticals' FCF Margin history runs 18 years deep, the most recent figure standing at 205.06% for Q2 2026.
- In Q2 2026, FCF Margin rose 17430.0% year-over-year to 205.06%; the TTM figure through Jun 2026 stood at 82.72% (down 5200.0% YoY), while the FY2025 annual figure was 33.91%, up 4355.0% from the prior year.
- FCF Margin for Q2 2026 stood at 205.06%, up from 1629.16% in the prior quarter.
- The five-year high for FCF Margin was 205.06% in Q2 2026, with the low at 1629.16% in Q1 2026.
- The 5-year median for FCF Margin is 69.8% (2024), against an average of 136.24%.
- Peak annual rise in FCF Margin reached 17430 bps in 2026, while the deepest fall reached 150505 bps in 2026.
- Ionis Pharmaceuticals' FCF Margin stood at 134.53% in 2022, then soared by 108 bps to 10.38% in 2023, then plunged by 702 bps to 62.51% in 2024, then declined by 25 bps to 78.2% in 2025, then surged by 362 bps to 205.06% in 2026.
- Business Quant data shows IONS's FCF Margin at 205.06% in Q2 2026, 1629.16% in Q1 2026, and 78.2% in Q4 2025.
Powered by 
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | FCF Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 128.13 Bn | 120.28 Bn | 2.84 Bn | 30.39% |
| 2 | Regeneron Pharmaceuticals | 112.33 Bn | 104.33 Bn | 3.93 Bn | 13.35% |
| 3 | Argenx Se | 53.24 Bn | 48.05 Bn | 1.41 Bn | - |
| 4 | Revolution Medicines | 43.64 Bn | 43.64 Bn | - | - |
| 5 | BeOne Medicines | 39.27 Bn | 34.17 Bn | 1.53 Bn | 25.68% |
| 6 | MindWalk Holdings | 35.32 Bn | 35.31 Bn | 1.82 Bn | -77,594.17% |
| 7 | Royalty Pharma | 33.72 Bn | 35.84 Bn | - | 70.82% |
| 8 | Alnylam Pharmaceuticals | 30.58 Bn | 27.27 Bn | 992.69 Mn | 22.62% |
| 9 | Insmed | 27.01 Bn | 25.85 Bn | 358.27 Mn | -22.35% |
| 10 | Ionis Pharmaceuticals | 9.48 Bn | 7.43 Bn | 265.21 Mn | 205.06% |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | 205.06% |
| Mar 31, 2026 | -1,629.16% |
| Dec 31, 2025 | -78.20% |
| Sep 30, 2025 | -87.23% |
| Jun 30, 2025 | 30.76% |
| Mar 31, 2025 | -124.12% |
| Dec 31, 2024 | -62.51% |
| Sep 30, 2024 | -92.70% |
| Jun 30, 2024 | -55.99% |
| Mar 31, 2024 | -129.23% |
| Dec 31, 2023 | 10.38% |
| Sep 30, 2023 | -77.09% |
| Jun 30, 2023 | -58.05% |
| Mar 31, 2023 | -110.68% |
| Dec 31, 2022 | -134.53% |
| Sep 30, 2022 | -18.76% |
| Jun 30, 2022 | -16.02% |
| Mar 31, 2022 | -24.21% |
| Dec 31, 2021 | 45.72% |
| Sep 30, 2021 | -44.25% |