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Ionis Pharmaceuticals (IONS) FCF Margin: 2009-2025

Historic FCF Margin for Ionis Pharmaceuticals (IONS) over the last 16 years, with Sep 2025 value amounting to -87.23%.

  • Ionis Pharmaceuticals' FCF Margin rose 547.00% to -87.23% in Q3 2025 from the same period last year, while for Sep 2025 it was -38.17%, marking a year-over-year increase of 802.00%. This contributed to the annual value of -77.46% for FY2024, which is 3540.00% down from last year.
  • As of Q3 2025, Ionis Pharmaceuticals' FCF Margin stood at -87.23%, which was down 274.42% from 50.01% recorded in Q2 2025.
  • In the past 5 years, Ionis Pharmaceuticals' FCF Margin ranged from a high of 50.01% in Q2 2025 and a low of -134.53% during Q4 2022.
  • Over the past 3 years, Ionis Pharmaceuticals' median FCF Margin value was -77.09% (recorded in 2023), while the average stood at -67.02%.
  • Per our database at Business Quant, Ionis Pharmaceuticals' FCF Margin skyrocketed by 35,683bps in 2021 and then plummeted by 18,025bps in 2022.
  • Quarterly analysis of 5 years shows Ionis Pharmaceuticals' FCF Margin stood at 45.72% in 2021, then crashed by 18,025bps to -134.53% in 2022, then spiked by 14,491bps to 10.38% in 2023, then crashed by 7,289bps to -62.51% in 2024, then surged by 547bps to -87.23% in 2025.
  • Its last three reported values are -87.23% in Q3 2025, 50.01% for Q2 2025, and -124.12% during Q1 2025.