Growth Metrics

Ionis Pharmaceuticals (IONS) FCF Margin (2016 - 2025)

Ionis Pharmaceuticals (IONS) has 17 years of FCF Margin data on record, last reported at 2238.14% in Q4 2025.

  • For Q4 2025, FCF Margin rose 230065.0% year-over-year to 2238.14%; the TTM value through Dec 2025 reached 47.92%, up 6590.0%, while the annual FY2025 figure was 1558.69%, 163615.0% up from the prior year.
  • FCF Margin reached 2238.14% in Q4 2025 per IONS's latest filing, up from 87.23% in the prior quarter.
  • Across five years, FCF Margin topped out at 2238.14% in Q4 2025 and bottomed at 420380.0% in Q2 2024.
  • Average FCF Margin over 5 years is 21012.88%, with a median of 60.28% recorded in 2023.
  • Peak YoY movement for FCF Margin: plummeted -42032195bps in 2024, then surged 42043001bps in 2025.
  • A 5-year view of FCF Margin shows it stood at 335.31% in 2021, then plummeted by -140bps to 134.53% in 2022, then skyrocketed by 108bps to 10.38% in 2023, then crashed by -702bps to 62.51% in 2024, then skyrocketed by 3680bps to 2238.14% in 2025.
  • Per Business Quant database, its latest 3 readings for FCF Margin were 2238.14% in Q4 2025, 87.23% in Q3 2025, and 50.01% in Q2 2025.