Ionis Pharmaceuticals (IONS) FCF Margin (2009 - 2026)
Ionis Pharmaceuticals (IONS) posted FCF Margin of 205.06% for Q2 2026, up 174.30 percentage points from 30.76% a year earlier and up 536.07 percentage points from the prior quarter.
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Analysis
Ionis Pharmaceuticals (IONS) FCF Margin (2009 - 2026) Analysis & Trends
For the trailing twelve months through Jun 30, 2026, FCF Margin at Ionis Pharmaceuticals was -64.16%, down 33.44 percentage points year-over-year; for FY2025, it was -33.91%, up 43.55 percentage points from FY2024.
- Annual FCF Margin shows a five-year change of -34.02 percentage points (FY2020 to FY2025).
- In prior years, Ionis Pharmaceuticals' FCF Margin was -77.46% in FY2024 (-35.40 pp), -42.06% in FY2023 (+7.32 pp), -49.39% in FY2022 (-51.71 pp) and 2.33% in FY2021 (+2.22 pp).
- The Q2 2026 figure stands as the highest quarterly FCF Margin since Q2 2018.
- On a year-over-year basis, FCF Margin increased in four of the last eight quarters, with an average year-over-year change of -4.93 percentage points.
- The strongest year-over-year quarter for FCF Margin in the past five years was Q2 2026, with a gain of 174.30 percentage points; the weakest was Q1 2026, with a drop of 206.89 percentage points.
- According to Business Quant data, FCF Margin for the three prior quarters was -331.01% (Q1 2026), -78.20% (Q4 2025) and -87.23% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | FCF Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 28.82% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 18.33% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | 26.96% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | 43.05% |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 34.72% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 34.70% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | 44.00% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 2.01% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 30.39% |
| 10 | Ionis Pharmaceuticals | 7.55 Bn | -1.34 Bn | 265.21 Mn | 205.06% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 205.06% |
| Mar 31, 2026 | -331.01% |
| Dec 31, 2025 | -78.20% |
| Sep 30, 2025 | -87.23% |
| Jun 30, 2025 | 30.76% |
| Mar 31, 2025 | -124.12% |
| Dec 31, 2024 | -62.51% |
| Sep 30, 2024 | -92.70% |
| Jun 30, 2024 | -55.99% |
| Mar 31, 2024 | -129.23% |
| Dec 31, 2023 | 10.38% |
| Sep 30, 2023 | -77.09% |
| Jun 30, 2023 | -58.05% |
| Mar 31, 2023 | -110.68% |
| Dec 31, 2022 | -134.53% |
| Sep 30, 2022 | -18.76% |
| Jun 30, 2022 | -16.02% |
| Mar 31, 2022 | -24.21% |
| Dec 31, 2021 | 45.72% |
| Sep 30, 2021 | -44.25% |
API Access
Ionis Pharmaceuticals FCF Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=fcf-margin&ticker=IONS&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "fcf-margin", "ticker": "IONS", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=fcf-margin&ticker=IONS&period=max&api_key=YOUR_API_KEY");
const data = await res.json();