Ionis Pharmaceuticals (IONS) EBT Margin (2009 - 2026)
Ionis Pharmaceuticals (IONS) recorded quarterly EBT Margin of 37.51% in Q1 2026, up 66.77% quarter-over-quarter from 112.87% in Q4 2025, and up 7405.0% on a YoY basis from 0.5% in Q1 2025.
Ionis Pharmaceuticals (IONS) EBT Margin (2009 - 2026) Analysis & Trends
Ionis Pharmaceuticals' EBT Margin history runs 18 years deep, the most recent figure standing at 37.51% for Q1 2026.
- In Q1 2026, EBT Margin rose 7405.0% year-over-year to 37.51%; the TTM figure through Mar 2026 stood at 53.72% (up 1109.0% YoY), while the FY2025 annual figure was 40.39%, up 2494.0% from the prior year.
- EBT Margin was 37.51% for Q1 2026 at Ionis Pharmaceuticals, up from 112.87% in the prior quarter.
- In the past five years, EBT Margin ranged from a high of 6176.55% in Q2 2025 to a low of 119.44% in Q1 2024.
- Historically, EBT Margin has averaged 301.28% across 5 years, with a median of 47.53% in 2024.
- The sharpest annual moves came in 2022 and 2025: EBT Margin sank 8045 bps in 2022, then soared 620594 bps in 2025.
- A 5-year view of EBT Margin shows it stood at 29.52% in 2022, then soared by 97 bps to 0.85% in 2023, then tumbled by 5474 bps to 47.53% in 2024, then plunged by 137 bps to 112.87% in 2025, then jumped by 67 bps to 37.51% in 2026.
- The last three EBT Margin figures came in at 37.51% (Q1 2026), 112.87% (Q4 2025), and 81.93% (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBT Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | - |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | 6.40% |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | - |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 41.95% |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | - |
| 10 | Ionis Pharmaceuticals | 12.23 Bn | 10.31 Bn | 243.11 Mn | -37.51% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -37.51% |
| Dec 31, 2025 | -112.87% |
| Sep 30, 2025 | -81.93% |
| Jun 30, 2025 | 6,176.55% |
| Mar 31, 2025 | -111.56% |
| Dec 31, 2024 | -47.53% |
| Sep 30, 2024 | -107.69% |
| Jun 30, 2024 | -29.39% |
| Mar 31, 2024 | -119.44% |
| Dec 31, 2023 | -0.85% |
| Sep 30, 2023 | -97.64% |
| Jun 30, 2023 | -41.11% |
| Mar 31, 2023 | -86.53% |
| Dec 31, 2022 | -29.52% |
| Sep 30, 2022 | -29.24% |
| Jun 30, 2022 | -76.89% |
| Mar 31, 2022 | -45.15% |
| Dec 31, 2021 | 50.93% |
| Sep 30, 2021 | -62.94% |
| Jun 30, 2021 | -64.05% |