KPIs & Operating Metrics(New)
Balance Sheet
Cash Flow Statement
Daily Values
Growth Metrics
Income Statement
Others
Ratios
Asset Utilization RatioAssets AverageDebt RatioDebt to EquityEBIT MarginEBITDA MarginEBT MarginEnterprise ValueEquity AverageEquity RatioFCF MarginGross MarginInterest Coverage RatioInventory AverageInvested CapitalMarket CapitalizationNet MarginOperating MarginReturn on AssetsReturn on Capital EmployedReturn on EquityReturn on Invested CapitalReturn on SalesTimes Interest Earned

Ionis Pharmaceuticals (IONS) EBT Margin: 2009-2025

Historic EBT Margin for Ionis Pharmaceuticals (IONS) over the last 17 years, with Sep 2025 value amounting to -81.93%.

  • Ionis Pharmaceuticals' EBT Margin rose 2576.00% to -81.93% in Q3 2025 from the same period last year, while for Sep 2025 it was -32.71%, marking a year-over-year increase of 1169.00%. This contributed to the annual value of -65.34% for FY2024, which is 2284.00% down from last year.
  • Ionis Pharmaceuticals' EBT Margin amounted to -81.93% in Q3 2025, which was down 284.37% from 44.44% recorded in Q2 2025.
  • Ionis Pharmaceuticals' EBT Margin's 5-year high stood at 50.93% during Q4 2021, with a 5-year trough of -119.44% in Q1 2024.
  • Over the past 3 years, Ionis Pharmaceuticals' median EBT Margin value was -81.93% (recorded in 2025), while the average stood at -61.77%.
  • Per our database at Business Quant, Ionis Pharmaceuticals' EBT Margin spiked by 20,884bps in 2021 and then tumbled by 8,045bps in 2022.
  • Over the past 5 years, Ionis Pharmaceuticals' EBT Margin (Quarterly) stood at 50.93% in 2021, then tumbled by 8,045bps to -29.52% in 2022, then spiked by 2,844bps to -1.08% in 2023, then plummeted by 4,644bps to -47.53% in 2024, then soared by 2,576bps to -81.93% in 2025.
  • Its last three reported values are -81.93% in Q3 2025, 44.44% for Q2 2025, and -111.56% during Q1 2025.