Ionis Pharmaceuticals (IONS) Debt Ratio (2009 - 2026)

Ionis Pharmaceuticals (IONS) posted quarterly Debt Ratio of 0.13 for Q1 2026, down 3.98% quarter-over-quarter from 0.13 in Q4 2025.

Ionis Pharmaceuticals (IONS) Debt Ratio (2009 - 2026) Analysis & Trends

Ionis Pharmaceuticals' Debt Ratio history runs 18 years deep, the most recent figure standing at 0.13 for Q1 2026.

In Q1 2026, Debt Ratio changed N/A year-over-year to 0.13; the TTM figure through Mar 2026 stood at 0.13 (changed N/A YoY), while the FY2025 annual figure was 0.13, up 655.25% from the prior year.
Debt Ratio for Q1 2026 stood at 0.13, down from 0.13 in the prior quarter.
The five-year high for Debt Ratio was 0.21 in Q2 2025, with the low at 0.0 in Q1 2023.
The 5-year median for Debt Ratio is 0.03 (2022), against an average of 0.06.
The sharpest annual moves came in 2023 and 2025: Debt Ratio slumped 87.92% in 2023, then surged 1341.29% in 2025.
Ionis Pharmaceuticals' Debt Ratio stood at 0.01 in 2022, then jumped by 357.15% to 0.03 in 2023, then sank by 40.01% to 0.02 in 2024, then soared by 655.25% to 0.13 in 2025, then declined by 3.98% to 0.13 in 2026.
Business Quant data shows IONS's Debt Ratio at 0.13 in Q1 2026, 0.13 in Q4 2025, and 0.21 in Q3 2025.

#	Company	Market Cap	Enterprise Value	Gross Profit (Qtr)	Debt Ratio (Qtr)
1	Vertex Pharmaceuticals	128.13 Bn	120.28 Bn	2.84 Bn	-
2	Regeneron Pharmaceuticals	112.33 Bn	104.33 Bn	3.93 Bn	0.05
3	Argenx Se	53.24 Bn	48.05 Bn	1.41 Bn	-
4	Revolution Medicines	43.64 Bn	43.64 Bn	-	-
5	BeOne Medicines	39.27 Bn	34.17 Bn	1.53 Bn	0.12
6	MindWalk Holdings	35.32 Bn	35.31 Bn	1.82 Bn	-
7	Royalty Pharma	33.72 Bn	35.84 Bn	-	0.47
8	Alnylam Pharmaceuticals	30.58 Bn	27.27 Bn	992.69 Mn	-
9	Insmed	27.01 Bn	25.85 Bn	358.27 Mn	0.26
10	Ionis Pharmaceuticals	9.48 Bn	7.43 Bn	265.21 Mn	-

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