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Asset Utilization RatioAssets AverageDebt RatioDebt to EquityEBIT MarginEBITDA MarginEBT MarginEnterprise ValueEquity AverageEquity RatioFCF MarginGross MarginInterest Coverage RatioInventory AverageInvested CapitalNet MarginOperating MarginReturn on AssetsReturn on Capital EmployedReturn on EquityReturn on Invested CapitalReturn on SalesTimes Interest Earned

Ionis Pharmaceuticals (IONS) Return on Assets (2016 - 2025)

Ionis Pharmaceuticals has reported Return on Assets over the past 16 years, most recently at 0.0% for Q4 2025.

  • Quarterly results put Return on Assets at 0.0% for Q4 2025, up 15.0% from a year ago — trailing twelve months through Dec 2025 was 0.0% (up 15.0% YoY), and the annual figure for FY2025 was 0.0%, up 15.0%.
  • Return on Assets for Q4 2025 was 0.0% at Ionis Pharmaceuticals, up from 0.09% in the prior quarter.
  • Over the last five years, Return on Assets for IONS hit a ceiling of 0.0% in Q3 2022 and a floor of 0.16% in Q1 2025.
  • Median Return on Assets over the past 5 years was 0.11% (2022), compared with a mean of 0.09%.
  • Biggest five-year swings in Return on Assets: dropped -14bps in 2023 and later rose 15bps in 2025.
  • Ionis Pharmaceuticals' Return on Assets stood at 0.01% in 2021, then plummeted by -858bps to 0.11% in 2022, then dropped by -14bps to 0.12% in 2023, then fell by -21bps to 0.15% in 2024, then surged by 100bps to 0.0% in 2025.
  • The last three reported values for Return on Assets were 0.0% (Q4 2025), 0.09% (Q3 2025), and 0.09% (Q2 2025) per Business Quant data.