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Asset Utilization RatioAssets AverageDebt RatioDebt to EquityEBIT MarginEBITDA MarginEBT MarginEnterprise ValueEquity AverageEquity RatioFCF MarginGross MarginInterest Coverage RatioInventory AverageInvested CapitalMarket CapitalizationNet MarginOperating MarginReturn on AssetsReturn on Capital EmployedReturn on EquityReturn on Invested CapitalReturn on SalesTimes Interest Earned

Ionis Pharmaceuticals (IONS) Net Margin: 2009-2025

Historic Net Margin for Ionis Pharmaceuticals (IONS) over the last 17 years, with Sep 2025 value amounting to -82.06%.

  • Ionis Pharmaceuticals' Net Margin rose 2292.00% to -82.06% in Q3 2025 from the same period last year, while for Sep 2025 it was -32.41%, marking a year-over-year increase of 1236.00%. This contributed to the annual value of -64.46% for FY2024, which is 1786.00% down from last year.
  • As of Q3 2025, Ionis Pharmaceuticals' Net Margin stood at -82.06%, which was down 284.65% from 44.44% recorded in Q2 2025.
  • In the past 5 years, Ionis Pharmaceuticals' Net Margin ranged from a high of 50.85% in Q4 2021 and a low of -119.52% during Q1 2024.
  • For the 3-year period, Ionis Pharmaceuticals' Net Margin averaged around -63.22%, with its median value being -82.06% (2025).
  • Its Net Margin has fluctuated over the past 5 years, first surged by 92,065bps in 2021, then crashed by 8,570bps in 2022.
  • Ionis Pharmaceuticals' Net Margin (Quarterly) stood at 50.85% in 2021, then slumped by 8,570bps to -34.85% in 2022, then spiked by 3,177bps to -3.08% in 2023, then tumbled by 4,326bps to -46.35% in 2024, then soared by 2,292bps to -82.06% in 2025.
  • Its last three reported values are -82.06% in Q3 2025, 44.44% for Q2 2025, and -111.64% during Q1 2025.