Ionis Pharmaceuticals (IONS) Invested Capital (2009 - 2026)

Ionis Pharmaceuticals (IONS) posted quarterly Invested Capital of $432.5 million for Q1 2026, little changed quarter-over-quarter from $431.9 million in Q4 2025.

Ionis Pharmaceuticals (IONS) Invested Capital (2009 - 2026) Analysis & Trends

Ionis Pharmaceuticals' Invested Capital history runs 17 years deep, the most recent figure standing at $432.5 million for Q1 2026.

  • In Q1 2026, Invested Capital changed N/A year-over-year to $432.5 million; the TTM figure through Jun 2026 stood at $1.5 billion (up 121.67% YoY), while the FY2025 annual figure was $431.9 million, changed N/A from the prior year.
  • Invested Capital for Q1 2026 stood at $432.5 million, roughly flat from $431.9 million in the prior quarter.
  • The five-year high for Invested Capital was $630.9 million in Q3 2025, with the low at $4.2 million in Q1 2022.
  • The 5-year median for Invested Capital is $44.4 million (2024), against an average of $210.6 million.
  • The sharpest annual moves came in 2022 and 2025: Invested Capital slumped 93.2% in 2022, then jumped 1318.83% in 2025.
  • Ionis Pharmaceuticals' Invested Capital stood at $5.0 million in 2022, then surged by 791.99% to $44.3 million in 2023, then climbed by 0.3% to $44.5 million in 2024, then soared by 871.39% to $431.9 million in 2025, then grew by 0.13% to $432.5 million in 2026.
  • Business Quant data shows IONS's Invested Capital at $432.5 million in Q1 2026, $431.9 million in Q4 2025, and $630.9 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Invested Cap. (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn -
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn -
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn -
4 Revolution Medicines 43.64 Bn 43.64 Bn - -
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 190.90 Mn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn 2.57 Mn
7 Royalty Pharma 33.72 Bn 35.84 Bn - 380.00 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn -
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -
10 Ionis Pharmaceuticals 9.48 Bn 7.43 Bn 265.21 Mn -

Historic Data

Download Data
DateValue
Mar 31, 2026 432.50 Mn
Dec 31, 2025 431.95 Mn
Sep 30, 2025 630.91 Mn
Jun 30, 2025 630.12 Mn
Sep 30, 2024 44.47 Mn
Jun 30, 2024 44.42 Mn
Mar 31, 2024 44.38 Mn
Dec 31, 2023 44.33 Mn
Sep 30, 2022 4.97 Mn
Jun 30, 2022 4.73 Mn
Mar 31, 2022 4.21 Mn
Dec 31, 2021 3.53 Mn
Sep 30, 2021 61.94 Mn
Jun 30, 2021 61.88 Mn
Mar 31, 2021 61.82 Mn
Dec 31, 2020 308.81 Mn
Sep 30, 2020 5.85 Mn
Jun 30, 2020 4.97 Mn
Mar 31, 2020 4.15 Mn
Sep 30, 2019 2.06 Mn