Ionis Pharmaceuticals (IONS) Invested Capital (2009 - 2026)
Ionis Pharmaceuticals' Invested Capital came in at $439.74 million for Q2 2026, down 65.2% from $1.26 billion a year earlier and down 52.4% from the prior quarter.
Ionis Pharmaceuticals (IONS) Invested Capital (2009 - 2026) Analysis & Trends
For FY2025, Ionis Pharmaceuticals' Invested Capital was $949.16 million, up 48.2% from FY2024.
- Invested Capital carries a five-year compound annual growth rate of -3.1% (FY2020 to FY2025).
- Going back by year, Invested Capital was $640.28 million in FY2024 (+35.4%), $472.85 million in FY2023 (-19.7%), $588.86 million in FY2022 (-29.5%) and $834.98 million in FY2021 (-24.9%).
- The Q2 2026 figure represents the lowest quarterly Invested Capital since Q2 2024.
- Year-over-year, Invested Capital increased in four of the last five quarters, with growth averaging 80.9%.
- The fastest year-over-year change in Invested Capital over five years came in Q2 2025 (growth of 309.5%), and the weakest in Q2 2026 (a decline of 65.2%).
- Business Quant data shows IONS's Invested Capital at $923.91 million (Q1 2026), $949.16 million (Q4 2025) and $1.25 billion (Q3 2025) in the three quarters before Q2 2026.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Invested Cap. (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 638.12 Bn | 556.64 Bn | 17.26 Bn | 134.01 Bn |
| 2 | AbbVie | 462.60 Bn | 435.75 Bn | 12.70 Bn | 64.89 Bn |
| 3 | Merck | 358.70 Bn | 313.13 Bn | 12.21 Bn | 95.89 Bn |
| 4 | Novartis Ag | 272.16 Bn | 228.03 Bn | 11.24 Bn | 79.44 Bn |
| 5 | Astrazeneca | 250.36 Bn | 223.92 Bn | 12.86 Bn | 50.26 Bn |
| 6 | Amgen | 227.87 Bn | 183.27 Bn | 7.24 Bn | 68.99 Bn |
| 7 | Gilead Sciences | 184.97 Bn | 159.08 Bn | 6.22 Bn | 38.08 Bn |
| 8 | Pfizer | 162.61 Bn | 109.56 Bn | 10.94 Bn | 148.69 Bn |
| 9 | Vertex Pharmaceuticals | 132.45 Bn | 104.46 Bn | 2.84 Bn | - |
| 10 | Ionis Pharmaceuticals | 7.40 Bn | -1.50 Bn | 265.21 Mn | 439.74 Mn |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 439.74 Mn |
| Mar 31, 2026 | 923.91 Mn |
| Dec 31, 2025 | 949.16 Mn |
| Sep 30, 2025 | 1.25 Bn |
| Jun 30, 2025 | 1.26 Bn |
| Dec 31, 2024 | 640.28 Mn |
| Sep 30, 2024 | 706.94 Mn |
| Jun 30, 2024 | 308.12 Mn |
| Mar 31, 2024 | 340.89 Mn |
| Dec 31, 2023 | 472.85 Mn |
| Mar 31, 2023 | 495.38 Mn |
| Dec 31, 2022 | 588.86 Mn |
| Sep 30, 2022 | 658.31 Mn |
| Jun 30, 2022 | 688.68 Mn |
| Mar 31, 2022 | 773.24 Mn |
| Dec 31, 2021 | 834.98 Mn |
| Sep 30, 2021 | 652.43 Mn |
| Jun 30, 2021 | 704.57 Mn |
| Mar 31, 2021 | 802.38 Mn |
| Dec 31, 2020 | 1.11 Bn |
Ionis Pharmaceuticals Invested Capital API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=invested-capital&ticker=IONS&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "invested-capital", "ticker": "IONS", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=invested-capital&ticker=IONS&period=max&api_key=YOUR_API_KEY");
const data = await res.json();