Ionis Pharmaceuticals (IONS) Invested Capital (2009 - 2026)

Ionis Pharmaceuticals' (IONS) quarterly Invested Capital came in at $432.5 million in Q1 2026, little changed quarter-over-quarter from $431.9 million in Q4 2025.

Ionis Pharmaceuticals (IONS) Invested Capital (2009 - 2026) Analysis & Trends

Ionis Pharmaceuticals' Invested Capital history runs 17 years deep, the most recent figure standing at $432.5 million for Q1 2026.

  • On a quarterly basis, Invested Capital changed N/A year-over-year to $432.5 million in Q1 2026; TTM through Mar 2026 was $2.1 billion, a 2291.16% increase from a year earlier, with the FY2025 full-year figure at $431.9 million, changed N/A from the prior year.
  • Invested Capital was little changed at $432.5 million in Q1 2026 per IONS's latest filing, from $431.9 million in the prior quarter.
  • Across five years, Invested Capital topped out at $630.9 million in Q3 2025 and bottomed at $4.2 million in Q1 2022.
  • The 5-year median for Invested Capital is $44.4 million (2024), against an average of $210.6 million.
  • Across the five-year window, Invested Capital tumbled 93.2% in 2022 and jumped 1318.83% in 2025, its largest moves.
  • Year by year, Invested Capital stood at $5.0 million in 2022, then soared by 791.99% to $44.3 million in 2023, then grew by 0.3% to $44.5 million in 2024, then jumped by 871.39% to $431.9 million in 2025, then increased by 0.13% to $432.5 million in 2026.
  • Per Business Quant, the three latest IONS Invested Capital figures stand at $432.5 million (Q1 2026), $431.9 million (Q4 2025), and $630.9 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Invested Cap. (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - 110.96 Mn
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 116.14 Mn
4 NuCana 279.75 Bn 279.75 Bn - -
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn -
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn -
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -
9 Revolution Medicines 37.78 Bn 37.78 Bn - -
10 Ionis Pharmaceuticals 9.21 Bn 7.29 Bn 243.11 Mn 432.50 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 432.50 Mn
Dec 31, 2025 431.95 Mn
Sep 30, 2025 630.91 Mn
Jun 30, 2025 630.12 Mn
Sep 30, 2024 44.47 Mn
Jun 30, 2024 44.42 Mn
Mar 31, 2024 44.38 Mn
Dec 31, 2023 44.33 Mn
Sep 30, 2022 4.97 Mn
Jun 30, 2022 4.73 Mn
Mar 31, 2022 4.21 Mn
Dec 31, 2021 3.53 Mn
Sep 30, 2021 61.94 Mn
Jun 30, 2021 61.88 Mn
Mar 31, 2021 61.82 Mn
Dec 31, 2020 7.30 Mn
Sep 30, 2020 5.85 Mn
Jun 30, 2020 4.97 Mn
Mar 31, 2020 4.15 Mn
Sep 30, 2019 2.06 Mn