Growth Metrics

Ionis Pharmaceuticals (IONS) Invested Capital (2016 - 2025)

Ionis Pharmaceuticals has reported Invested Capital over the past 17 years, most recently at $921.0 million for Q4 2025.

  • Quarterly results put Invested Capital at $921.0 million for Q4 2025, up 56.55% from a year ago — trailing twelve months through Dec 2025 was $921.0 million (up 56.55% YoY), and the annual figure for FY2025 was $921.0 million, up 56.55%.
  • Invested Capital for Q4 2025 was $921.0 million at Ionis Pharmaceuticals, down from $1.2 billion in the prior quarter.
  • Over the last five years, Invested Capital for IONS hit a ceiling of $1.3 billion in Q2 2025 and a floor of $308.1 million in Q2 2024.
  • Median Invested Capital over the past 5 years was $589.5 million (2021), compared with a mean of $633.5 million.
  • Biggest five-year swings in Invested Capital: crashed 65.04% in 2021 and later skyrocketed 309.53% in 2025.
  • Ionis Pharmaceuticals' Invested Capital stood at $775.3 million in 2021, then decreased by 26.1% to $572.9 million in 2022, then decreased by 24.76% to $431.0 million in 2023, then surged by 36.5% to $588.4 million in 2024, then skyrocketed by 56.55% to $921.0 million in 2025.
  • The last three reported values for Invested Capital were $921.0 million (Q4 2025), $1.2 billion (Q3 2025), and $1.3 billion (Q2 2025) per Business Quant data.