Ionis Pharmaceuticals IONS
NASDAQ IONS
$43.41 -0.59 (-1.34%)
As of: Oct 2, 2026 · 2:22 PM EDT

Ionis Pharmaceuticals (IONS) Invested Capital (2009 - 2026)

Updated

Ionis Pharmaceuticals' Invested Capital came in at $439.74 million for Q2 2026, down 65.2% from $1.26 billion a year earlier and down 52.4% from the prior quarter.

Analysis

Ionis Pharmaceuticals (IONS) Invested Capital (2009 - 2026) Analysis & Trends

For FY2025, Ionis Pharmaceuticals' Invested Capital was $949.16 million, up 48.2% from FY2024.

  • Invested Capital carries a five-year compound annual growth rate of -3.1% (FY2020 to FY2025).
  • Going back by year, Invested Capital was $640.28 million in FY2024 (+35.4%), $472.85 million in FY2023 (-19.7%), $588.86 million in FY2022 (-29.5%) and $834.98 million in FY2021 (-24.9%).
  • The Q2 2026 figure represents the lowest quarterly Invested Capital since Q2 2024.
  • Year-over-year, Invested Capital increased in four of the last five quarters, with growth averaging 80.9%.
  • The fastest year-over-year change in Invested Capital over five years came in Q2 2025 (growth of 309.5%), and the weakest in Q2 2026 (a decline of 65.2%).
  • Business Quant data shows IONS's Invested Capital at $923.91 million (Q1 2026), $949.16 million (Q4 2025) and $1.25 billion (Q3 2025) in the three quarters before Q2 2026.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Invested Cap. (Qtr)
1 Johnson & Johnson 638.12 Bn 556.64 Bn 17.26 Bn 134.01 Bn
2 AbbVie 462.60 Bn 435.75 Bn 12.70 Bn 64.89 Bn
3 Merck 358.70 Bn 313.13 Bn 12.21 Bn 95.89 Bn
4 Novartis Ag 272.16 Bn 228.03 Bn 11.24 Bn 79.44 Bn
5 Astrazeneca 250.36 Bn 223.92 Bn 12.86 Bn 50.26 Bn
6 Amgen 227.87 Bn 183.27 Bn 7.24 Bn 68.99 Bn
7 Gilead Sciences 184.97 Bn 159.08 Bn 6.22 Bn 38.08 Bn
8 Pfizer 162.61 Bn 109.56 Bn 10.94 Bn 148.69 Bn
9 Vertex Pharmaceuticals 132.45 Bn 104.46 Bn 2.84 Bn -
10 Ionis Pharmaceuticals 7.40 Bn -1.50 Bn 265.21 Mn 439.74 Mn
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 439.74 Mn
Mar 31, 2026 923.91 Mn
Dec 31, 2025 949.16 Mn
Sep 30, 2025 1.25 Bn
Jun 30, 2025 1.26 Bn
Dec 31, 2024 640.28 Mn
Sep 30, 2024 706.94 Mn
Jun 30, 2024 308.12 Mn
Mar 31, 2024 340.89 Mn
Dec 31, 2023 472.85 Mn
Mar 31, 2023 495.38 Mn
Dec 31, 2022 588.86 Mn
Sep 30, 2022 658.31 Mn
Jun 30, 2022 688.68 Mn
Mar 31, 2022 773.24 Mn
Dec 31, 2021 834.98 Mn
Sep 30, 2021 652.43 Mn
Jun 30, 2021 704.57 Mn
Mar 31, 2021 802.38 Mn
Dec 31, 2020 1.11 Bn
API Access

Ionis Pharmaceuticals Invested Capital API

Pull this series into your own models, spreadsheets and apps with the Business Quant Historical Metrics API. The request below matches the chart above — change the frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.

https://data.businessquant.com/historic?slug=invested-capital&ticker=IONS&period=max&api_key=YOUR_API_KEY