Ionis Pharmaceuticals (IONS) Invested Capital (2009 - 2026)

Ionis Pharmaceuticals (IONS) recorded quarterly Invested Capital of $923.9 million in Q1 2026, little changed quarter-over-quarter from $921.0 million in Q4 2025, and up 94.21% on a YoY basis from $475.7 million in Q1 2025.

Ionis Pharmaceuticals (IONS) Invested Capital (2009 - 2026) Analysis & Trends

Ionis Pharmaceuticals' Invested Capital history runs 18 years deep, the most recent figure standing at $923.9 million for Q1 2026.

  • In Q1 2026, Invested Capital rose 94.21% year-over-year to $923.9 million; the TTM figure through Mar 2026 stood at $923.9 million (up 94.21% YoY), while the FY2025 annual figure was $921.0 million, up 56.55% from the prior year.
  • Invested Capital was $923.9 million for Q1 2026 at Ionis Pharmaceuticals, roughly flat from $921.0 million in the prior quarter.
  • In the past five years, Invested Capital ranged from a high of $1.3 billion in Q2 2025 to a low of $308.1 million in Q2 2024.
  • Historically, Invested Capital has averaged $644.3 million across 5 years, with a median of $588.4 million in 2024.
  • The sharpest annual moves came in 2023 and 2025: Invested Capital plunged 47.36% in 2023, then surged 309.53% in 2025.
  • A 5-year view of Invested Capital shows it stood at $572.9 million in 2022, then dropped by 24.76% to $431.0 million in 2023, then jumped by 36.5% to $588.4 million in 2024, then soared by 56.55% to $921.0 million in 2025, then climbed by 0.31% to $923.9 million in 2026.
  • The last three Invested Capital figures came in at $923.9 million (Q1 2026), $921.0 million (Q4 2025), and $1.2 billion (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Invested Cap. (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - 7.14 Bn
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - 795.79 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - 595,226.00
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 1.00 Bn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - 14.38 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 19.36 Bn
9 Abivax 91.96 Bn 91.96 Bn - 502.95 Mn
10 Ionis Pharmaceuticals 12.23 Bn 10.31 Bn 243.11 Mn 923.91 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 923.91 Mn
Dec 31, 2025 921.04 Mn
Sep 30, 2025 1.25 Bn
Jun 30, 2025 1.26 Bn
Mar 31, 2025 475.73 Mn
Dec 31, 2024 588.35 Mn
Sep 30, 2024 706.94 Mn
Jun 30, 2024 308.12 Mn
Mar 31, 2024 340.89 Mn
Dec 31, 2023 431.02 Mn
Sep 30, 2023 315.46 Mn
Jun 30, 2023 428.30 Mn
Mar 31, 2023 486.57 Mn
Dec 31, 2022 572.89 Mn
Sep 30, 2022 599.33 Mn
Jun 30, 2022 629.46 Mn
Mar 31, 2022 713.78 Mn
Dec 31, 2021 775.26 Mn
Sep 30, 2021 592.47 Mn
Jun 30, 2021 644.55 Mn