Ionis Pharmaceuticals (IONS) Invested Capital (2009 - 2026)
Ionis Pharmaceuticals (IONS) recorded quarterly Invested Capital of $923.9 million in Q1 2026, little changed quarter-over-quarter from $921.0 million in Q4 2025, and up 94.21% on a YoY basis from $475.7 million in Q1 2025.
Ionis Pharmaceuticals (IONS) Invested Capital (2009 - 2026) Analysis & Trends
Ionis Pharmaceuticals' Invested Capital history runs 18 years deep, the most recent figure standing at $923.9 million for Q1 2026.
- In Q1 2026, Invested Capital rose 94.21% year-over-year to $923.9 million; the TTM figure through Mar 2026 stood at $923.9 million (up 94.21% YoY), while the FY2025 annual figure was $921.0 million, up 56.55% from the prior year.
- Invested Capital was $923.9 million for Q1 2026 at Ionis Pharmaceuticals, roughly flat from $921.0 million in the prior quarter.
- In the past five years, Invested Capital ranged from a high of $1.3 billion in Q2 2025 to a low of $308.1 million in Q2 2024.
- Historically, Invested Capital has averaged $644.3 million across 5 years, with a median of $588.4 million in 2024.
- The sharpest annual moves came in 2023 and 2025: Invested Capital plunged 47.36% in 2023, then surged 309.53% in 2025.
- A 5-year view of Invested Capital shows it stood at $572.9 million in 2022, then dropped by 24.76% to $431.0 million in 2023, then jumped by 36.5% to $588.4 million in 2024, then soared by 56.55% to $921.0 million in 2025, then climbed by 0.31% to $923.9 million in 2026.
- The last three Invested Capital figures came in at $923.9 million (Q1 2026), $921.0 million (Q4 2025), and $1.2 billion (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Invested Cap. (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | 7.14 Bn |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | 795.79 Mn |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | 595,226.00 |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | 1.00 Bn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | 14.38 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 19.36 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | 502.95 Mn |
| 10 | Ionis Pharmaceuticals | 12.23 Bn | 10.31 Bn | 243.11 Mn | 923.91 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 923.91 Mn |
| Dec 31, 2025 | 921.04 Mn |
| Sep 30, 2025 | 1.25 Bn |
| Jun 30, 2025 | 1.26 Bn |
| Mar 31, 2025 | 475.73 Mn |
| Dec 31, 2024 | 588.35 Mn |
| Sep 30, 2024 | 706.94 Mn |
| Jun 30, 2024 | 308.12 Mn |
| Mar 31, 2024 | 340.89 Mn |
| Dec 31, 2023 | 431.02 Mn |
| Sep 30, 2023 | 315.46 Mn |
| Jun 30, 2023 | 428.30 Mn |
| Mar 31, 2023 | 486.57 Mn |
| Dec 31, 2022 | 572.89 Mn |
| Sep 30, 2022 | 599.33 Mn |
| Jun 30, 2022 | 629.46 Mn |
| Mar 31, 2022 | 713.78 Mn |
| Dec 31, 2021 | 775.26 Mn |
| Sep 30, 2021 | 592.47 Mn |
| Jun 30, 2021 | 644.55 Mn |