Ionis Pharmaceuticals (IONS) Return on Sales (2009 - 2026)

Ionis Pharmaceuticals (IONS) posted quarterly Return on Sales of 0.0% for Q2 2026, down 1.0% year-over-year from 0.0% in Q2 2025, and up 76.88% quarter-over-quarter from 0.02% in Q1 2026.

Ionis Pharmaceuticals (IONS) Return on Sales (2009 - 2026) Analysis & Trends

Ionis Pharmaceuticals' Return on Sales history runs 18 years deep, the most recent figure standing at 0.0% for Q2 2026.

  • In Q2 2026, Return on Sales fell 1.0% year-over-year to 0.0%; the TTM figure through Jun 2026 stood at 0.01% (down 1.0% YoY), while the FY2025 annual figure was 0.0%, changed 0.0% from the prior year.
  • Return on Sales for Q2 2026 stood at 0.0%, up from 0.02% in the prior quarter.
  • The five-year high for Return on Sales was 0.0% in Q4 2023, with the low at 0.02% in Q1 2026.
  • The 5-year median for Return on Sales is 0.01% (2022), against an average of 0.01%.
  • The sharpest annual moves came in 2023 and 2025: Return on Sales decreased 1 bps in 2023, then rose 1 bps in 2025.
  • Ionis Pharmaceuticals' Return on Sales stood at 0.0% in 2022, then jumped by 233 bps to 0.0% in 2023, then plunged by 123 bps to 0.0% in 2024, then sank by 1043 bps to 0.01% in 2025, then jumped by 42 bps to 0.0% in 2026.
  • Business Quant data shows IONS's Return on Sales at 0.0% in Q2 2026, 0.02% in Q1 2026, and 0.01% in Q4 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROS (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 0.00%
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 0.00%
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 0.00%
4 Revolution Medicines 43.64 Bn 43.64 Bn - -
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 0.00%
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn 0.00%
7 Royalty Pharma 33.72 Bn 35.84 Bn - 0.00%
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 0.00%
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn 0.00%
10 Ionis Pharmaceuticals 9.48 Bn 7.43 Bn 265.21 Mn 0.00%

Historic Data

Download Data
DateValue
Jun 30, 2026 0.00%
Mar 31, 2026 -0.02%
Dec 31, 2025 -0.01%
Sep 30, 2025 -0.01%
Jun 30, 2025 0.00%
Mar 31, 2025 -0.01%
Dec 31, 2024 0.00%
Sep 30, 2024 -0.01%
Jun 30, 2024 0.00%
Mar 31, 2024 -0.01%
Dec 31, 2023 0.00%
Sep 30, 2023 -0.01%
Jun 30, 2023 0.00%
Mar 31, 2023 -0.01%
Dec 31, 2022 0.00%
Sep 30, 2022 0.00%
Jun 30, 2022 -0.01%
Mar 31, 2022 0.00%
Dec 31, 2021 0.00%
Sep 30, 2021 -0.01%