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Ionis Pharmaceuticals (IONS) Return on Sales (2016 - 2025)

Historic Return on Sales for Ionis Pharmaceuticals (IONS) over the last 17 years, with Q3 2025 value amounting to 0.82%.

  • Ionis Pharmaceuticals' Return on Sales rose 2300.0% to 0.82% in Q3 2025 from the same period last year, while for Sep 2025 it was 0.32%, marking a year-over-year increase of 1200.0%. This contributed to the annual value of 0.64% for FY2024, which is 1800.0% down from last year.
  • Per Ionis Pharmaceuticals' latest filing, its Return on Sales stood at 0.82% for Q3 2025, which was up 2300.0% from 0.44% recorded in Q2 2025.
  • Over the past 5 years, Ionis Pharmaceuticals' Return on Sales peaked at 0.51% during Q4 2021, and registered a low of 1.2% during Q1 2024.
  • For the 5-year period, Ionis Pharmaceuticals' Return on Sales averaged around 0.55%, with its median value being 0.62% (2021).
  • Per our database at Business Quant, Ionis Pharmaceuticals' Return on Sales soared by 92100bps in 2021 and then tumbled by -8600bps in 2022.
  • Ionis Pharmaceuticals' Return on Sales (Quarter) stood at 0.51% in 2021, then crashed by -169bps to 0.35% in 2022, then surged by 91bps to 0.03% in 2023, then crashed by -1403bps to 0.46% in 2024, then tumbled by -77bps to 0.82% in 2025.
  • Its Return on Sales was 0.82% in Q3 2025, compared to 0.44% in Q2 2025 and 1.12% in Q1 2025.