Ionis Pharmaceuticals (IONS) Return on Invested Capital (2010 - 2026)

Ionis Pharmaceuticals' Return on Invested Capital history runs 16 years deep, the most recent figure standing at 0.0% for Q1 2026.

• On a quarterly basis, Return on Invested Capital rose 4.0% year-over-year to 0.0% in Q1 2026; TTM through Mar 2026 was 0.0%, a 4.0% increase from a year earlier, with the FY2021 full-year figure at 0.09%, changed N/A from the prior year.
• Return on Invested Capital rose to 0.0% in Q1 2026 per IONS's latest filing, from 0.0% in the prior quarter.
• Across five years, Return on Invested Capital topped out at 0.0% in Q3 2022 and bottomed at 0.67% in Q2 2023.
• The 5-year median for Return on Invested Capital is 0.03% (2024), against an average of 0.11%.
• Across the five-year window, Return on Invested Capital plunged 67 bps in 2023 and surged 61 bps in 2024, its largest moves.
• Year by year, Return on Invested Capital stood at 0.26% in 2022, then slumped by 160 bps to 0.67% in 2023, then soared by 96 bps to 0.03% in 2024, then soared by 91 bps to 0.0% in 2025, then gained by 28 bps to 0.0% in 2026.
• Per Business Quant, the three latest IONS Return on Invested Capital figures stand at 0.0% (Q1 2026), 0.0% (Q4 2025), and 0.0% (Q3 2025).