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Asset Utilization RatioAssets AverageDebt RatioDebt to EquityEBIT MarginEBITDA MarginEBT MarginEnterprise ValueEquity AverageEquity RatioFCF MarginGross MarginInterest Coverage RatioInventory AverageInvested CapitalNet MarginOperating MarginReturn on AssetsReturn on Capital EmployedReturn on EquityReturn on Invested CapitalReturn on SalesTimes Interest Earned

Ionis Pharmaceuticals (IONS) Return on Invested Capital (2016 - 2025)

Ionis Pharmaceuticals (IONS) has 15 years of Return on Invested Capital data on record, last reported at 0.22% in Q3 2025.

  • For Q3 2025, Return on Invested Capital fell 2.0% year-over-year to 0.22%; the TTM value through Sep 2025 reached 0.22%, down 2.0%, while the annual FY2024 figure was 0.92%, 687.0% down from the prior year.
  • Return on Invested Capital reached 0.22% in Q3 2025 per IONS's latest filing, up from 0.3% in the prior quarter.
  • Across five years, Return on Invested Capital topped out at 8.0% in Q4 2023 and bottomed at 3.18% in Q1 2021.
  • Average Return on Invested Capital over 5 years is 0.25%, with a median of 0.47% recorded in 2024.
  • Peak YoY movement for Return on Invested Capital: surged 873bps in 2023, then crashed -872bps in 2024.
  • A 5-year view of Return on Invested Capital shows it stood at 0.07% in 2021, then tumbled by -930bps to 0.73% in 2022, then skyrocketed by 1193bps to 8.0% in 2023, then plummeted by -109bps to 0.72% in 2024, then skyrocketed by 70bps to 0.22% in 2025.
  • Per Business Quant database, its latest 3 readings for Return on Invested Capital were 0.22% in Q3 2025, 0.3% in Q2 2025, and 0.88% in Q1 2025.