Ionis Pharmaceuticals (IONS) Debt to Equity (2009 - 2026)

Ionis Pharmaceuticals (IONS) recorded quarterly Debt to Equity of $0.88 in Q1 2026, down 6.44% quarter-over-quarter from $0.94 in Q4 2025.

Ionis Pharmaceuticals (IONS) Debt to Equity (2009 - 2026) Analysis & Trends

Ionis Pharmaceuticals' Debt to Equity history runs 18 years deep, the most recent figure standing at $0.88 for Q1 2026.

  • In Q1 2026, Debt to Equity changed N/A year-over-year to $0.88; the TTM figure through Mar 2026 stood at $0.88 (changed N/A YoY), while the FY2025 annual figure was $0.94, up 965.86% from the prior year.
  • Debt to Equity was $0.88 for Q1 2026 at Ionis Pharmaceuticals, down from $0.94 in the prior quarter.
  • In the past five years, Debt to Equity ranged from a high of $1.02 in Q3 2025 to a low of $0.02 in Q1 2023.
  • Historically, Debt to Equity has averaged $0.34 across 5 years, with a median of $0.13 in 2024.
  • The sharpest annual moves came in 2023 and 2025: Debt to Equity plunged 79.82% in 2023, then surged 1421.0% in 2025.
  • A 5-year view of Debt to Equity shows it stood at $0.03 in 2022, then jumped by 699.23% to $0.22 in 2023, then plunged by 60.4% to $0.09 in 2024, then surged by 965.86% to $0.94 in 2025, then slipped by 6.44% to $0.88 in 2026.
  • The last three Debt to Equity figures came in at $0.88 (Q1 2026), $0.94 (Q4 2025), and $1.02 (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Debt/Equity (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 0.32
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn -
9 Abivax 91.96 Bn 91.96 Bn - -
10 Ionis Pharmaceuticals 12.23 Bn 10.31 Bn 243.11 Mn 0.88

Historic Data

Download Data
DateValue
Mar 31, 2026 0.88
Dec 31, 2025 0.94
Sep 30, 2025 1.02
Jun 30, 2025 1.00
Dec 31, 2024 0.09
Sep 30, 2024 0.07
Jun 30, 2024 0.17
Mar 31, 2024 0.15
Dec 31, 2023 0.22
Mar 31, 2023 0.02
Dec 31, 2022 0.03
Sep 30, 2022 0.05
Jun 30, 2022 0.10
Mar 31, 2022 0.09
Dec 31, 2021 0.08
Sep 30, 2021 0.23
Jun 30, 2021 0.21
Mar 31, 2021 0.05
Dec 31, 2020 0.04
Sep 30, 2020 0.04