Ionis Pharmaceuticals Inc (IONS) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

159,765,000Shares Outstanding
171,764,182Shares held by institutions
$13,139,959,923Value of institutional holdings
107.51%Institutional ownership %
12.80%Shares Changed QoQ
486No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Ionis Pharmaceuticals Inc (NASDAQ:IONS) appears in 480 institutional 13F filings for the quarter ending December 2025.

485 Institutional Holders

171,764,182 Total Shares Held
Download Data
Owner Name Date Shares Held Change (QoQ) Change (%) Value (USD)
FMR LLC 31 Mar, 2026 24,556,637 484,536 2.01% $1,843,957,873.00
Capital World Investors 31 Mar, 2026 21,186,369 3,225,070 17.96% $1,590,884,448.00
BlackRock, Inc. 31 Mar, 2026 10,442,476 -205,387 -1.93% $784,125,524.00
VANGUARD PORTFOLIO MANAGEMENT LLC 31 Mar, 2026 7,808,902 7,808,902 0.00% $586,370,451.00
VANGUARD CAPITAL MANAGEMENT LLC 31 Mar, 2026 7,118,330 7,118,330 0.00% $534,515,400.00
WELLINGTON MANAGEMENT GROUP LLP 31 Mar, 2026 6,391,816 131,491 2.10% $479,961,465.00
T. Rowe Price Investment Management, Inc. 31 Mar, 2026 6,159,027 -8,738,855 -58.66% $462,482.00
TWO SIGMA INVESTMENTS, LP 31 Mar, 2026 5,857,629 3,198,983 120.32% $439,849,362.00
State Street Corp 31 Mar, 2026 3,995,564 20,699 0.52% $300,026,901.00
GEODE CAPITAL MANAGEMENT, LLC 31 Mar, 2026 3,984,332 835,483 26.53% $305,196,969.00
Royal Bank Of Canada 31 Mar, 2026 3,801,815 2,683,018 239.81% $285,477,000.00
PRICE T ROWE ASSOCIATES INC /MD/ 31 Mar, 2026 3,025,251 3,025,251 0.00% $227,167.00
Jpmorgan Chase & Co 31 Mar, 2026 2,363,567 58,775 2.55% $171,405,902.00
Tweedy, Browne Co LLC 31 Mar, 2026 2,275,625 -189,305 -7.68% $170,876,681.00
Artisan Partners Limited Partnership 31 Mar, 2026 2,058,308 876,892 74.22% $154,558,340.00
BAKER BROS. ADVISORS LP 31 Mar, 2026 2,047,727 255,886 14.28% $153,763,820.00
DEERFIELD MANAGEMENT COMPANY, L.P. 31 Mar, 2026 1,979,669 0 0.00% $148,653,345.00
Deep Track Capital, LP 31 Mar, 2026 1,950,000 250,000 14.71% $146,425,500.00
Bellevue Group AG 31 Mar, 2026 1,818,665 -2,983,534 -62.13% $136,563,555.00
Goldman Sachs Group Inc 31 Mar, 2026 1,699,847 -12,085 -0.71% $127,641,511.00