Ionis Pharmaceuticals IONS Institutional Ownership

NASDAQ IONS

$58.47 +0.34 (+0.59%)

As of: Sep 4, 2026 · 11:51 AM EDT

Institutions by Trading Activity

514 Institutions

Increased 270 52.5%

Unchanged 85 16.5%

Reduced 159 30.9%

Ownership Statistics

13F · as of 30 Jun, 2026

Institutional Ownership

109.66%

▲+4.94 pp QoQ

Shares Held by Institutions

181.40Mn

of 165.42Mn outstanding

▲+5.78% QoQ

Shares Outstanding

165.42Mn

-15.98Mn held outside 13F filers

Institutional Investors

514

filed 13F for Jun 2026

▲+20 vs prior quarter

Net Shares Added (QoQ)

+9.91Mn

accumulated since last quarter

Value of Holdings

$10.54Bn

reported market value

Shares Owned by Institutions

Shares held % of outstanding

Latest —

Average ownership —

Peak ownership —

Shares Purchased/Sold by Institutions

Accumulated Distributed

Latest quarter —

Net over range —

Accumulating quarters —

Ownership Summary

Quarter ending 30 Jun, 2026

Ionis Pharmaceuticals Inc (NASDAQ:IONS) showed up in the 13F filings of 514 institutional investors as of June 2026.

Collectively, these holders controlled 109.7% of Ionis Pharmaceuticals's outstanding shares in June 2026, up from 104.7% in March 2026.
Their total shares held in IONS increased 5.78% from the prior quarter, while the number of investors in Ionis Pharmaceuticals increased 41.21% year over year.
Activity in IONS broke down as 270 buyers, 159 sellers, and 85 unchanged among 514 total holders.
Altogether, these fund groups held 181.4Mn shares in IONS by June 2026, up by 9.91Mn shares quarter on quarter, and up 11.14Mn shares year over year.
As of June 30, 2026, the biggest holder of Ionis Pharmaceuticals is FMR LLC at 24.63Mn shares, representing 14.89% of shares outstanding.
Leading buyers of Ionis Pharmaceuticals shares for the quarter ending June 2026 were Royal Bank Of Canada (2.38Mn), Sixth Street Partners Management Company, L.P. (1.61Mn), Barclays Plc (1.31Mn), WELLINGTON MANAGEMENT GROUP LLP (1.26Mn), Alyeska Investment Group, L.P. (944.77K).
Top sellers of IONS stock for the quarter ending June 2026 included T. Rowe Price Investment Management, Inc. (2.2Mn), Bellevue Group AG (846.41K), MILLENNIUM MANAGEMENT LLC (762.63K), CITADEL ADVISORS LLC (706.25K), SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC (616.77K).
Per Business Quant data, the top 10 holders of Ionis Pharmaceuticals for the quarter ending June 2026 are FMR LLC (24.63Mn), Capital World Investors (21.67Mn), BlackRock, Inc. (10.7Mn), VANGUARD PORTFOLIO MANAGEMENT LLC (7.86Mn), WELLINGTON MANAGEMENT GROUP LLP (7.65Mn), VANGUARD CAPITAL MANAGEMENT LLC (7.21Mn), TWO SIGMA INVESTMENTS, LP (6.25Mn), Royal Bank Of Canada (6.18Mn), State Street Corp (4.33Mn), T. Rowe Price Investment Management, Inc. (3.96Mn).

Form 13F Holdings

514 Institutional Holders

Report period 30 Jun, 2026

Total shares held 181.40Mn

Of outstanding 109.66%

#	Institution	CIK	Shares Held	% of Outstanding	Change (QoQ)	Change (%)	Value (USD)
1	FMR LLC	0000315066	24,631,956	14.89%	▲75,319	+0.31%	$1.95Bn
2	Capital World Investors	0001422849	21,669,226	13.10%	▲482,857	+2.28%	$1.72Bn
3	BlackRock, Inc.	0002012383	10,704,660	6.47%	▲262,184	+2.51%	$848.77Mn
4	VANGUARD PORTFOLIO MANAGEMENT LLC	0002100121	7,859,529	4.75%	▲50,627	+0.65%	$623.18Mn
5	WELLINGTON MANAGEMENT GROUP LLP	0000902219	7,651,415	4.63%	▲1,259,599	+19.71%	$606.68Mn
6	VANGUARD CAPITAL MANAGEMENT LLC	0002100119	7,211,497	4.36%	▲93,167	+1.31%	$571.80Mn
7	TWO SIGMA INVESTMENTS, LP	0001179392	6,252,342	3.78%	▲394,713	+6.74%	$495.75Mn
8	Royal Bank Of Canada	0001000275	6,182,479	3.74%	▲2,380,664	+62.62%	$490.21Mn
9	State Street Corp	0000093751	4,334,848	2.62%	▲339,284	+8.49%	$343.71Mn
10	T. Rowe Price Investment Management, Inc.	0001897612	3,959,372	2.39%	▼2,199,655	-35.71%	$313.94K
11	GEODE CAPITAL MANAGEMENT, LLC	0001214717	3,584,024	2.17%	▼400,308	-10.05%	$294.75Mn
12	PRICE T ROWE ASSOCIATES INC /MD/	0000080255	3,184,500	1.93%	▲159,249	+5.26%	$252.50K
13	Jpmorgan Chase & Co	0000019617	2,671,717	1.62%	▲308,150	+13.04%	$216.20Mn
14	Artisan Partners Limited Partnership	0001466153	2,640,024	1.60%	▲581,716	+28.26%	$209.33Mn
15	Tweedy, Browne Co LLC	0000732905	2,280,311	1.38%	▲4,686	+0.21%	$180.81Mn
16	Deep Track Capital, LP	0001856083	2,200,000	1.33%	▲250,000	+12.82%	$174.44Mn
17	Goldman Sachs Group Inc	0000886982	2,109,945	1.28%	▲410,098	+24.13%	$167.30Mn
18	BAKER BROS. ADVISORS LP	0001263508	2,047,727	1.24%	0	0.00%	$162.36Mn
19	DEERFIELD MANAGEMENT COMPANY, L.P.	0001009258	1,979,669	1.20%	0	0.00%	$156.97Mn
20	AMERICAN CENTURY COMPANIES INC	0000748054	1,947,076	1.18%	▲283,273	+17.03%	$154.38Mn

Showing 1 to 20 of 514 holders