Ionis Pharmaceuticals (IONS) Enterprise Value (2009 - 2026)

Ionis Pharmaceuticals (IONS) recorded quarterly Enterprise Value of -$1.9 billion in Q1 2026, up 28.32% quarter-over-quarter from -$2.7 billion in Q4 2025, and up 10.54% on a YoY basis from -$1.7 billion in Q1 2025.

Ionis Pharmaceuticals (IONS) Enterprise Value (2009 - 2026) Analysis & Trends

Ionis Pharmaceuticals' Enterprise Value history runs 18 years deep, the most recent figure standing at -$1.9 billion for Q1 2026.

  • In Q1 2026, Enterprise Value rose 10.54% year-over-year to -$1.9 billion; the TTM figure through Mar 2026 stood at -$1.9 billion (up 10.54% YoY), while the FY2025 annual figure was -$2.7 billion, down 16.53% from the prior year.
  • Enterprise Value was -$1.9 billion for Q1 2026 at Ionis Pharmaceuticals, up from -$2.7 billion in the prior quarter.
  • In the past five years, Enterprise Value ranged from a high of -$1.9 billion in Q1 2026 to a low of -$2.7 billion in Q4 2025.
  • Historically, Enterprise Value has averaged -$2.2 billion across 5 years, with a median of -$2.2 billion in 2023.
  • The sharpest annual moves came in 2023 and 2024: Enterprise Value fell 17.98% in 2023, then climbed 12.86% in 2024.
  • A 5-year view of Enterprise Value shows it stood at -$2.0 billion in 2022, then slipped by 17.33% to -$2.3 billion in 2023, then advanced by 1.44% to -$2.3 billion in 2024, then fell by 16.53% to -$2.7 billion in 2025, then increased by 28.32% to -$1.9 billion in 2026.
  • The last three Enterprise Value figures came in at -$1.9 billion (Q1 2026), -$2.7 billion (Q4 2025), and -$2.2 billion (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -32.30 Mn
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -4.14 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -286.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -18.44 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -2.77 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -7.20 Mn
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn -7.25 Bn
9 Abivax 91.96 Bn 91.96 Bn - -584.73 Mn
10 Ionis Pharmaceuticals 12.23 Bn 10.31 Bn 243.11 Mn -1.92 Bn

Historic Data

Download Data
DateValue
Mar 31, 2026 -1.92 Bn
Dec 31, 2025 -2.68 Bn
Sep 30, 2025 -2.24 Bn
Jun 30, 2025 -2.29 Bn
Mar 31, 2025 -2.15 Bn
Dec 31, 2024 -2.30 Bn
Sep 30, 2024 -2.48 Bn
Jun 30, 2024 -2.08 Bn
Mar 31, 2024 -2.21 Bn
Dec 31, 2023 -2.33 Bn
Sep 30, 2023 -2.24 Bn
Jun 30, 2023 -2.39 Bn
Mar 31, 2023 -2.35 Bn
Dec 31, 2022 -1.99 Bn
Sep 30, 2022 -1.98 Bn
Jun 30, 2022 -2.02 Bn
Mar 31, 2022 -2.05 Bn
Dec 31, 2021 -2.11 Bn
Sep 30, 2021 -1.99 Bn
Jun 30, 2021 -2.06 Bn