Ionis Pharmaceuticals (IONS) Enterprise Value (2009 - 2026)

Ionis Pharmaceuticals (IONS) posted quarterly Enterprise Value of -$2.1 billion for Q2 2026, up 10.28% year-over-year from -$1.9 billion in Q2 2025, and down 7.06% quarter-over-quarter from -$1.9 billion in Q1 2026.

Ionis Pharmaceuticals (IONS) Enterprise Value (2009 - 2026) Analysis & Trends

Ionis Pharmaceuticals' Enterprise Value history runs 18 years deep, the most recent figure standing at -$2.1 billion for Q2 2026.

  • In Q2 2026, Enterprise Value rose 10.28% year-over-year to -$2.1 billion; the TTM figure through Jun 2026 stood at -$2.1 billion (up 10.28% YoY), while the FY2025 annual figure was -$2.7 billion, down 16.53% from the prior year.
  • Enterprise Value for Q2 2026 stood at -$2.1 billion, down from -$1.9 billion in the prior quarter.
  • The five-year high for Enterprise Value was -$1.9 billion in Q1 2026, with the low at -$2.7 billion in Q4 2025.
  • The 5-year median for Enterprise Value is -$2.2 billion (2023), against an average of -$2.2 billion.
  • The sharpest annual moves came in 2023 and 2024: Enterprise Value declined 17.98% in 2023, then advanced 12.86% in 2024.
  • Ionis Pharmaceuticals' Enterprise Value stood at -$2.0 billion in 2022, then decreased by 17.33% to -$2.3 billion in 2023, then gained by 1.44% to -$2.3 billion in 2024, then declined by 16.53% to -$2.7 billion in 2025, then gained by 23.26% to -$2.1 billion in 2026.
  • Business Quant data shows IONS's Enterprise Value at -$2.1 billion in Q2 2026, -$1.9 billion in Q1 2026, and -$2.7 billion in Q4 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn -7.85 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn -7.99 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn -5.18 Bn
4 Revolution Medicines 43.64 Bn 43.64 Bn - -3.94 Bn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn -5.10 Bn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -8.46 Mn
7 Royalty Pharma 33.72 Bn 35.84 Bn - 2.12 Bn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn -3.31 Bn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -1.16 Bn
10 Ionis Pharmaceuticals 9.48 Bn 7.43 Bn 265.21 Mn -2.05 Bn

Historic Data

Download Data
DateValue
Jun 30, 2026 -2.05 Bn
Mar 31, 2026 -1.92 Bn
Dec 31, 2025 -2.68 Bn
Sep 30, 2025 -2.24 Bn
Jun 30, 2025 -2.29 Bn
Mar 31, 2025 -2.15 Bn
Dec 31, 2024 -2.30 Bn
Sep 30, 2024 -2.48 Bn
Jun 30, 2024 -2.08 Bn
Mar 31, 2024 -2.21 Bn
Dec 31, 2023 -2.33 Bn
Sep 30, 2023 -2.24 Bn
Jun 30, 2023 -2.39 Bn
Mar 31, 2023 -2.35 Bn
Dec 31, 2022 -1.99 Bn
Sep 30, 2022 -1.98 Bn
Jun 30, 2022 -2.02 Bn
Mar 31, 2022 -2.05 Bn
Dec 31, 2021 -2.11 Bn
Sep 30, 2021 -1.99 Bn