Ionis Pharmaceuticals (IONS) Enterprise Value (2009 - 2026)

Ionis Pharmaceuticals' (IONS) quarterly Enterprise Value came in at -$1.9 billion in Q1 2026, up 10.54% year-on-year from -$1.7 billion in Q1 2025, and up 28.32% quarter-over-quarter from -$2.7 billion in Q4 2025.

Ionis Pharmaceuticals (IONS) Enterprise Value (2009 - 2026) Analysis & Trends

Ionis Pharmaceuticals' Enterprise Value history runs 18 years deep, the most recent figure standing at -$1.9 billion for Q1 2026.

  • On a quarterly basis, Enterprise Value rose 10.54% year-over-year to -$1.9 billion in Q1 2026; TTM through Mar 2026 was -$1.9 billion, a 10.54% increase from a year earlier, with the FY2025 full-year figure at -$2.7 billion, down 16.53% from the prior year.
  • Enterprise Value grew to -$1.9 billion in Q1 2026 per IONS's latest filing, from -$2.7 billion in the prior quarter.
  • Across five years, Enterprise Value topped out at -$1.9 billion in Q1 2026 and bottomed at -$2.7 billion in Q4 2025.
  • The 5-year median for Enterprise Value is -$2.2 billion (2023), against an average of -$2.2 billion.
  • Across the five-year window, Enterprise Value decreased 17.98% in 2023 and increased 12.86% in 2024, its largest moves.
  • Year by year, Enterprise Value stood at -$2.0 billion in 2022, then slipped by 17.33% to -$2.3 billion in 2023, then advanced by 1.44% to -$2.3 billion in 2024, then fell by 16.53% to -$2.7 billion in 2025, then increased by 28.32% to -$1.9 billion in 2026.
  • Per Business Quant, the three latest IONS Enterprise Value figures stand at -$1.9 billion (Q1 2026), -$2.7 billion (Q4 2025), and -$2.2 billion (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -283.54 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -61.40 Mn
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn -4.79 Bn
4 NuCana 279.75 Bn 279.75 Bn - -32.26 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn -7.25 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn -8.75 Bn
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -5.18 Bn
9 Revolution Medicines 37.78 Bn 37.78 Bn - -1.91 Bn
10 Ionis Pharmaceuticals 9.21 Bn 7.29 Bn 243.11 Mn -1.92 Bn

Historic Data

Download Data
DateValue
Mar 31, 2026 -1.92 Bn
Dec 31, 2025 -2.68 Bn
Sep 30, 2025 -2.24 Bn
Jun 30, 2025 -2.29 Bn
Mar 31, 2025 -2.15 Bn
Dec 31, 2024 -2.30 Bn
Sep 30, 2024 -2.48 Bn
Jun 30, 2024 -2.08 Bn
Mar 31, 2024 -2.21 Bn
Dec 31, 2023 -2.33 Bn
Sep 30, 2023 -2.24 Bn
Jun 30, 2023 -2.39 Bn
Mar 31, 2023 -2.35 Bn
Dec 31, 2022 -1.99 Bn
Sep 30, 2022 -1.98 Bn
Jun 30, 2022 -2.02 Bn
Mar 31, 2022 -2.05 Bn
Dec 31, 2021 -2.11 Bn
Sep 30, 2021 -1.99 Bn
Jun 30, 2021 -2.06 Bn