Stoke Therapeutics (STOK) EBITDA Margin (2022 - 2026)

Stoke Therapeutics' quarterly EBITDA Margin came in at 813.31% in Q1 2026, down 88452.0% year-on-year from N/an in Q1 2025, and up 80.28% quarter-over-quarter from 4125.32% in Q4 2025.

Stoke Therapeutics has reported EBITDA Margin for 5 years, with the latest figure at 813.31% in Q1 2026.

  • For the quarter ending Q1 2026, EBITDA Margin fell 88452.0% year-over-year to 813.31%; the trailing twelve-month figure through Mar 2026 stood at 529.23% (down 55551.0% YoY), and the FY2025 full-year result was 3.36%, up 24041.0% from the prior year.
  • EBITDA Margin for Q1 2026 stood at 813.31%, up from 4125.32% in the prior quarter.
  • The five-year high for EBITDA Margin was 71.22% in Q1 2025, with the low at 4125.32% in Q4 2025.
  • Average EBITDA Margin over 5 years is 810.76%, with a median of 734.89% recorded in 2023.
  • Year-over-year, EBITDA Margin surged 90996 bps in 2024 and slumped 407757 bps in 2025.
  • Tracing STOK's EBITDA Margin over 5 years: stood at 768.88% in 2022, then slipped by 25 bps to 957.71% in 2023, then soared by 95 bps to 47.75% in 2024, then sank by 8539 bps to 4125.32% in 2025, then jumped by 80 bps to 813.31% in 2026.
  • The last three EBITDA Margin figures came in at 813.31% (Q1 2026), 4125.32% (Q4 2025), and 357.38% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA Margin (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -6.43%
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 38.10%
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 18.35%
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 17.24%
10 Stoke Therapeutics 1.92 Bn 1.92 Bn - -813.31%

Historic Data

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DateValue
Mar 31, 2026 -813.31%
Dec 31, 2025 -4,125.32%
Sep 30, 2025 -357.38%
Jun 30, 2025 -168.51%
Mar 31, 2025 71.22%
Dec 31, 2024 -47.75%
Sep 30, 2024 -536.35%
Jun 30, 2024 -532.19%
Mar 31, 2024 -625.00%
Dec 31, 2023 -957.71%
Sep 30, 2023 -734.89%
Jun 30, 2023 -1,226.72%
Mar 31, 2023 -426.40%
Dec 31, 2022 -768.88%
Sep 30, 2022 -913.53%
Jun 30, 2022 -781.31%
Mar 31, 2022 -838.83%