Stoke Therapeutics (STOK) EBITDA Margin (2022 - 2026)
Stoke Therapeutics (STOK) reported EBITDA Margin of -696.74% for Q2 2026, down 502.39 percentage points from -194.35% a year earlier but up 153.78 percentage points from the prior quarter.
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Analysis
Stoke Therapeutics (STOK) EBITDA Margin (2022 - 2026) Analysis & Trends
Over the twelve months ended Jun 30, 2026, Stoke Therapeutics' EBITDA Margin came in at -803.26%, down 824.42 percentage points year-over-year; for FY2025, it was -10.19%, up 261.11 percentage points from FY2024.
- EBITDA Margin has a three-year change of +818.59 percentage points (FY2022 to FY2025).
- By year, EBITDA Margin came in at -271.30% in FY2024 (+1007.44 pp), -1278.74% in FY2023 (-449.96 pp) and -828.78% in FY2022.
- Five-year quarterly EBITDA Margin spans a low of -4351.21% in Q4 2025 and a high of 70.45% in Q1 2025.
- Year over year, EBITDA Margin has now declined in each of the last three quarters, with an average year-over-year change of -400.93 percentage points over the last eight quarters.
- The high point for year-over-year EBITDA Margin in five years was Q4 2024 (a gain of 974.57 percentage points); the low point was Q4 2025 (a drop of 4293.27 percentage points).
- Per Business Quant data, the three quarters before Q2 2026 came in at -850.52% (Q1 2026), -4351.21% (Q4 2025) and -401.14% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 35.95% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 49.01% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | 6.02% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | - |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 33.11% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 46.01% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -124.26% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 39.16% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 39.10% |
| 10 | Stoke Therapeutics | 1.59 Bn | 421.92 Mn | - | -696.74% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -696.74% |
| Mar 31, 2026 | -850.52% |
| Dec 31, 2025 | -4,351.21% |
| Sep 30, 2025 | -401.14% |
| Jun 30, 2025 | -194.35% |
| Mar 31, 2025 | 70.45% |
| Dec 31, 2024 | -57.95% |
| Sep 30, 2024 | -602.02% |
| Jun 30, 2024 | -596.03% |
| Mar 31, 2024 | -659.61% |
| Dec 31, 2023 | -1,032.51% |
| Sep 30, 2023 | -804.02% |
| Jun 30, 2023 | -1,316.04% |
| Mar 31, 2023 | -467.64% |
| Dec 31, 2022 | -812.94% |
| Sep 30, 2022 | -921.17% |
| Jun 30, 2022 | -771.77% |
| Mar 31, 2022 | -818.27% |
API Access
Stoke Therapeutics EBITDA Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=ebitda-margin&ticker=STOK&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "ebitda-margin", "ticker": "STOK", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=ebitda-margin&ticker=STOK&period=max&api_key=YOUR_API_KEY");
const data = await res.json();