Stoke Therapeutics (STOK) EBT Margin (2022 - 2026)

Stoke Therapeutics (STOK) posted quarterly EBT Margin of 802.75% for Q1 2026, down 87474.0% year-over-year from N/an in Q1 2025, and up 81.97% quarter-over-quarter from 4453.35% in Q4 2025.

Stoke Therapeutics (STOK) EBT Margin (2022 - 2026) Analysis & Trends

Stoke Therapeutics' EBT Margin history runs 5 years deep, the most recent figure standing at 802.75% for Q1 2026.

  • In Q1 2026, EBT Margin fell 87474.0% year-over-year to 802.75%; the TTM figure through Mar 2026 stood at 547.22% (down 57199.0% YoY), while the FY2025 annual figure was 110.77%, up 22276.0% from the prior year.
  • EBT Margin for Q1 2026 stood at 802.75%, up from 4453.35% in the prior quarter.
  • The five-year high for EBT Margin was 71.99% in Q1 2025, with the low at 5809.03% in Q4 2023.
  • The 5-year median for EBT Margin is 802.75% (2026), against an average of 1339.78%.
  • The sharpest annual moves came in 2024 and 2025: EBT Margin surged 574384 bps in 2024, then slumped 438816 bps in 2025.
  • Stoke Therapeutics' EBT Margin stood at 3811.14% in 2022, then tumbled by 52 bps to 5809.03% in 2023, then soared by 99 bps to 65.19% in 2024, then plunged by 6731 bps to 4453.35% in 2025, then jumped by 82 bps to 802.75% in 2026.
  • Business Quant data shows STOK's EBT Margin at 802.75% in Q1 2026, 4453.35% in Q4 2025, and 372.7% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBT Margin (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 41.75%
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 35.61%
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 34.77%
4 Revolution Medicines 43.64 Bn 43.64 Bn - -
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 18.33%
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -94.22%
7 Royalty Pharma 33.72 Bn 35.84 Bn - 12.09%
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 13.77%
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -2.67%
10 Stoke Therapeutics 1.95 Bn 1.66 Bn - -660.78%

Historic Data

Download Data
DateValue
Jun 30, 2026 -660.78%
Mar 31, 2026 -802.75%
Dec 31, 2025 -4,453.35%
Sep 30, 2025 -372.70%
Jun 30, 2025 -169.96%
Mar 31, 2025 71.99%
Dec 31, 2024 -65.19%
Sep 30, 2024 -540.05%
Jun 30, 2024 -531.88%
Mar 31, 2024 -625.57%
Dec 31, 2023 -5,809.03%
Sep 30, 2023 -821.46%
Jun 30, 2023 -1,495.04%
Mar 31, 2023 -479.64%
Dec 31, 2022 -3,811.14%
Sep 30, 2022 -1,007.85%
Jun 30, 2022 -996.16%
Mar 31, 2022 -866.50%